Affinity Data by Patent

Patent code US8703785

Found 9 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Beta-secretase 1 (Homo sapiens (Human))	BDBM120379 (US8703785, 44) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	7.0	30
Shionogi & Co., Ltd. US Patent					Assay Description First, 48.5 μl portions of a solution of substrate peptide (Biotin-XSEVNLDAEFRHDSGC-Eu: X=ε-amino-n-capronic acid, Eu=Europium cryptate) we...				US Patent US8703785 (2014) BindingDB Entry DOI: 10.7270/Q2MW2FSM
Shionogi & Co., Ltd. US Patent					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM120377 (US8703785, 40) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	7.0	30
Shionogi & Co., Ltd. US Patent					Assay Description First, 48.5 μl portions of a solution of substrate peptide (Biotin-XSEVNLDAEFRHDSGC-Eu: X=ε-amino-n-capronic acid, Eu=Europium cryptate) we...				US Patent US8703785 (2014) BindingDB Entry DOI: 10.7270/Q2MW2FSM
Shionogi & Co., Ltd. US Patent					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM120380 (US8703785, 34) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	37	n/a	n/a	n/a	n/a	7.0	30
Shionogi & Co., Ltd. US Patent					Assay Description First, 48.5 μl portions of a solution of substrate peptide (Biotin-XSEVNLDAEFRHDSGC-Eu: X=ε-amino-n-capronic acid, Eu=Europium cryptate) we...				US Patent US8703785 (2014) BindingDB Entry DOI: 10.7270/Q2MW2FSM
Shionogi & Co., Ltd. US Patent					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM120381 (US8703785, 35) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	42	n/a	n/a	n/a	n/a	7.0	30
Shionogi & Co., Ltd. US Patent					Assay Description First, 48.5 μl portions of a solution of substrate peptide (Biotin-XSEVNLDAEFRHDSGC-Eu: X=ε-amino-n-capronic acid, Eu=Europium cryptate) we...				US Patent US8703785 (2014) BindingDB Entry DOI: 10.7270/Q2MW2FSM
Shionogi & Co., Ltd. US Patent					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM120378 (US8703785, 43) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	56	n/a	n/a	n/a	n/a	7.0	30
Shionogi & Co., Ltd. US Patent					Assay Description First, 48.5 μl portions of a solution of substrate peptide (Biotin-XSEVNLDAEFRHDSGC-Eu: X=ε-amino-n-capronic acid, Eu=Europium cryptate) we...				US Patent US8703785 (2014) BindingDB Entry DOI: 10.7270/Q2MW2FSM
Shionogi & Co., Ltd. US Patent					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM120385 (US8703785, 482) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	73	n/a	n/a	n/a	n/a	7.0	30
Shionogi & Co., Ltd. US Patent					Assay Description First, 48.5 μl portions of a solution of substrate peptide (Biotin-XSEVNLDAEFRHDSGC-Eu: X=ε-amino-n-capronic acid, Eu=Europium cryptate) we...				US Patent US8703785 (2014) BindingDB Entry DOI: 10.7270/Q2MW2FSM
Shionogi & Co., Ltd. US Patent					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM120384 (US8703785, 481) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	180	n/a	n/a	n/a	n/a	7.0	30
Shionogi & Co., Ltd. US Patent					Assay Description First, 48.5 μl portions of a solution of substrate peptide (Biotin-XSEVNLDAEFRHDSGC-Eu: X=ε-amino-n-capronic acid, Eu=Europium cryptate) we...				US Patent US8703785 (2014) BindingDB Entry DOI: 10.7270/Q2MW2FSM
Shionogi & Co., Ltd. US Patent					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM120382 (US8703785, 473) Show SMILES COc1cnc(cn1)C(=O)Nc1cccc(CNc2cccnc2N)c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.99E+3	n/a	n/a	n/a	n/a	7.0	30
Shionogi & Co., Ltd. US Patent					Assay Description First, 48.5 μl portions of a solution of substrate peptide (Biotin-XSEVNLDAEFRHDSGC-Eu: X=ε-amino-n-capronic acid, Eu=Europium cryptate) we...				US Patent US8703785 (2014) BindingDB Entry DOI: 10.7270/Q2MW2FSM
Shionogi & Co., Ltd. US Patent					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM120383 (US8703785, 478) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.18E+3	n/a	n/a	n/a	n/a	7.0	30
Shionogi & Co., Ltd. US Patent					Assay Description First, 48.5 μl portions of a solution of substrate peptide (Biotin-XSEVNLDAEFRHDSGC-Eu: X=ε-amino-n-capronic acid, Eu=Europium cryptate) we...				US Patent US8703785 (2014) BindingDB Entry DOI: 10.7270/Q2MW2FSM
Shionogi & Co., Ltd. US Patent					More data for this Ligand-Target Pair

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* indicates data uncertainty>20%