Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Epidermal growth factor receptor [668-1210] (Homo sapiens (Human)) | BDBM50123162 (CHEMBL3622673 | US9388160, 11) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | 7.4 | 30 |
Teligene Ltd US Patent | Assay Description The assay was performed using Kinase-Glo Plus luminescence kinase assay kit (Promega). The compounds were diluted in 10% DMSO and 5 μl of the dilu... | US Patent US9388160 (2016) BindingDB Entry DOI: 10.7270/Q2T152J9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor [668-1210] (Homo sapiens (Human)) | BDBM50123162 (CHEMBL3622673 | US9388160, 11) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | 7.4 | 30 |
Teligene Ltd US Patent | Assay Description The assay was performed using Kinase-Glo Plus luminescence kinase assay kit (Promega). The compounds were diluted in 10% DMSO and 5 μl of the dilu... | US Patent US9388160 (2016) BindingDB Entry DOI: 10.7270/Q2T152J9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor [668-1210,T790M,L858R] (Homo sapiens (Human)) | BDBM50123163 (CHEMBL3622672 | US9388160, 12) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 22 | n/a | n/a | n/a | n/a | 7.4 | 30 |
Teligene Ltd US Patent | Assay Description The assay was performed using Kinase-Glo Plus luminescence kinase assay kit (Promega). The compounds were diluted in 10% DMSO and 5 μl of the dilu... | US Patent US9388160 (2016) BindingDB Entry DOI: 10.7270/Q2T152J9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor [668-1210,T790M,L858R] (Homo sapiens (Human)) | BDBM50123163 (CHEMBL3622672 | US9388160, 12) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 7.4 | 30 |
Teligene Ltd US Patent | Assay Description The assay was performed using Kinase-Glo Plus luminescence kinase assay kit (Promega). The compounds were diluted in 10% DMSO and 5 μl of the dilu... | US Patent US9388160 (2016) BindingDB Entry DOI: 10.7270/Q2T152J9 | |||||||||||
More data for this Ligand-Target Pair |