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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Amyloid beta-binding alcohol dehydrogenase (Homo sapiens (Human)) | BDBM232928 (US9346839, 9 | US9738668, Compound 9) | UniProtKB/TrEMBL GoogleScholar AffyNet  | PC cid PC sid UniChem | US Patent | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas US Patent | Assay Description The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 &#... | US Patent US9738668 (2017) BindingDB Entry DOI: 10.7270/Q22Z17NP | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amyloid beta-binding alcohol dehydrogenase (Homo sapiens (Human)) | BDBM232926 (US9346839, 7 | US9738668, Compound 7) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas US Patent | Assay Description The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 &#... | US Patent US9738668 (2017) BindingDB Entry DOI: 10.7270/Q22Z17NP | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amyloid beta-binding alcohol dehydrogenase (Homo sapiens (Human)) | BDBM232923 (US9346839, 4 | US9738668, Compound 4) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 5.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas US Patent | Assay Description The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 &#... | US Patent US9738668 (2017) BindingDB Entry DOI: 10.7270/Q22Z17NP | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amyloid beta-binding alcohol dehydrogenase (Homo sapiens (Human)) | BDBM232930 (US9346839, 11 | US9738668, Compound 11) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 9.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas US Patent | Assay Description The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 &#... | US Patent US9738668 (2017) BindingDB Entry DOI: 10.7270/Q22Z17NP | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amyloid beta-binding alcohol dehydrogenase (Homo sapiens (Human)) | BDBM232927 (US9346839, 8 | US9738668, Compound 8) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.49E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas US Patent | Assay Description To perform kinetic analyses of the binding of phosphonate derivatives to ABAD, the BIACORE 3000 instrument (based on surface plasmon resonance [SPR] ... | US Patent US9738668 (2017) BindingDB Entry DOI: 10.7270/Q22Z17NP | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amyloid beta-binding alcohol dehydrogenase (Homo sapiens (Human)) | BDBM232929 (US9346839, 10 | US9738668, Compound 10) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 3.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas US Patent | Assay Description The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 &#... | US Patent US9738668 (2017) BindingDB Entry DOI: 10.7270/Q22Z17NP | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amyloid beta-binding alcohol dehydrogenase (Homo sapiens (Human)) | BDBM232925 (US9346839, 6 | US9738668, Compound 6) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 4.49E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas US Patent | Assay Description The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 &#... | US Patent US9738668 (2017) BindingDB Entry DOI: 10.7270/Q22Z17NP | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amyloid beta-binding alcohol dehydrogenase (Homo sapiens (Human)) | BDBM232927 (US9346839, 8 | US9738668, Compound 8) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 7.06E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas US Patent | Assay Description The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 &#... | US Patent US9738668 (2017) BindingDB Entry DOI: 10.7270/Q22Z17NP | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amyloid beta-binding alcohol dehydrogenase (Homo sapiens (Human)) | BDBM232924 (US9346839, 5 | US9738668, Compound 5) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 9.11E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas US Patent | Assay Description The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 &#... | US Patent US9738668 (2017) BindingDB Entry DOI: 10.7270/Q22Z17NP | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amyloid beta-binding alcohol dehydrogenase (Homo sapiens (Human)) | BDBM232923 (US9346839, 4 | US9738668, Compound 4) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 9.66E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas US Patent | Assay Description To perform kinetic analyses of the binding of phosphonate derivatives to ABAD, the BIACORE 3000 instrument (based on surface plasmon resonance [SPR] ... | US Patent US9738668 (2017) BindingDB Entry DOI: 10.7270/Q22Z17NP | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amyloid beta-binding alcohol dehydrogenase (Homo sapiens (Human)) | BDBM232931 (US9346839, 15 | US9738668, Compound 15) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 3.56E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas US Patent | Assay Description To perform kinetic analyses of the binding of phosphonate derivatives to ABAD, the BIACORE 3000 instrument (based on surface plasmon resonance [SPR] ... | US Patent US9738668 (2017) BindingDB Entry DOI: 10.7270/Q22Z17NP | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amyloid beta-binding alcohol dehydrogenase (Homo sapiens (Human)) | BDBM232928 (US9346839, 9 | US9738668, Compound 9) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 7.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas US Patent | Assay Description The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 &#... | US Patent US9738668 (2017) BindingDB Entry DOI: 10.7270/Q22Z17NP | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amyloid beta-binding alcohol dehydrogenase (Homo sapiens (Human)) | BDBM232926 (US9346839, 7 | US9738668, Compound 7) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 9.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas US Patent | Assay Description The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 &#... | US Patent US9738668 (2017) BindingDB Entry DOI: 10.7270/Q22Z17NP | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amyloid beta-binding alcohol dehydrogenase (Homo sapiens (Human)) | BDBM232923 (US9346839, 4 | US9738668, Compound 4) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.96E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas US Patent | Assay Description The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 &#... | US Patent US9738668 (2017) BindingDB Entry DOI: 10.7270/Q22Z17NP | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amyloid beta-binding alcohol dehydrogenase (Homo sapiens (Human)) | BDBM232930 (US9346839, 11 | US9738668, Compound 11) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.41E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas US Patent | Assay Description The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 &#... | US Patent US9738668 (2017) BindingDB Entry DOI: 10.7270/Q22Z17NP | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amyloid beta-binding alcohol dehydrogenase (Homo sapiens (Human)) | BDBM232927 (US9346839, 8 | US9738668, Compound 8) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.27E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas US Patent | Assay Description To perform kinetic analyses of the binding of phosphonate derivatives to ABAD, the BIACORE 3000 instrument (based on surface plasmon resonance [SPR] ... | US Patent US9738668 (2017) BindingDB Entry DOI: 10.7270/Q22Z17NP | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amyloid beta-binding alcohol dehydrogenase (Homo sapiens (Human)) | BDBM232929 (US9346839, 10 | US9738668, Compound 10) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.25E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas US Patent | Assay Description The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 &#... | US Patent US9738668 (2017) BindingDB Entry DOI: 10.7270/Q22Z17NP | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amyloid beta-binding alcohol dehydrogenase (Homo sapiens (Human)) | BDBM232925 (US9346839, 6 | US9738668, Compound 6) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.65E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas US Patent | Assay Description The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 &#... | US Patent US9738668 (2017) BindingDB Entry DOI: 10.7270/Q22Z17NP | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amyloid beta-binding alcohol dehydrogenase (Homo sapiens (Human)) | BDBM232927 (US9346839, 8 | US9738668, Compound 8) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.59E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas US Patent | Assay Description The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 &#... | US Patent US9738668 (2017) BindingDB Entry DOI: 10.7270/Q22Z17NP | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amyloid beta-binding alcohol dehydrogenase (Homo sapiens (Human)) | BDBM232924 (US9346839, 5 | US9738668, Compound 5) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.35E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas US Patent | Assay Description The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 &#... | US Patent US9738668 (2017) BindingDB Entry DOI: 10.7270/Q22Z17NP | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amyloid beta-binding alcohol dehydrogenase (Homo sapiens (Human)) | BDBM232923 (US9346839, 4 | US9738668, Compound 4) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.41E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas US Patent | Assay Description To perform kinetic analyses of the binding of phosphonate derivatives to ABAD, the BIACORE 3000 instrument (based on surface plasmon resonance [SPR] ... | US Patent US9738668 (2017) BindingDB Entry DOI: 10.7270/Q22Z17NP | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amyloid beta-binding alcohol dehydrogenase (Homo sapiens (Human)) | BDBM232931 (US9346839, 15 | US9738668, Compound 15) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.26E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas US Patent | Assay Description To perform kinetic analyses of the binding of phosphonate derivatives to ABAD, the BIACORE 3000 instrument (based on surface plasmon resonance [SPR] ... | US Patent US9738668 (2017) BindingDB Entry DOI: 10.7270/Q22Z17NP | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amyloid beta-binding alcohol dehydrogenase (Homo sapiens (Human)) | BDBM232930 (US9346839, 11 | US9738668, Compound 11) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 380 | n/a | n/a | n/a | n/a | n/a |
University of Kansas US Patent | Assay Description The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 &#... | US Patent US9738668 (2017) BindingDB Entry DOI: 10.7270/Q22Z17NP | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amyloid beta-binding alcohol dehydrogenase (Homo sapiens (Human)) | BDBM232928 (US9346839, 9 | US9738668, Compound 9) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 264 | n/a | n/a | n/a | n/a | n/a |
University of Kansas US Patent | Assay Description The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 &#... | US Patent US9738668 (2017) BindingDB Entry DOI: 10.7270/Q22Z17NP | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amyloid beta-binding alcohol dehydrogenase (Homo sapiens (Human)) | BDBM232924 (US9346839, 5 | US9738668, Compound 5) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 954 | n/a | n/a | n/a | n/a | n/a |
University of Kansas US Patent | Assay Description The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 &#... | US Patent US9738668 (2017) BindingDB Entry DOI: 10.7270/Q22Z17NP | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amyloid beta-binding alcohol dehydrogenase (Homo sapiens (Human)) | BDBM232923 (US9346839, 4 | US9738668, Compound 4) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 496 | n/a | n/a | n/a | n/a | n/a |
University of Kansas US Patent | Assay Description The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 &#... | US Patent US9738668 (2017) BindingDB Entry DOI: 10.7270/Q22Z17NP | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amyloid beta-binding alcohol dehydrogenase (Homo sapiens (Human)) | BDBM232926 (US9346839, 7 | US9738668, Compound 7) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 256 | n/a | n/a | n/a | n/a | n/a |
University of Kansas US Patent | Assay Description The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 &#... | US Patent US9738668 (2017) BindingDB Entry DOI: 10.7270/Q22Z17NP | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amyloid beta-binding alcohol dehydrogenase (Homo sapiens (Human)) | BDBM232931 (US9346839, 15 | US9738668, Compound 15) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 264 | n/a | n/a | n/a | n/a | n/a |
University of Kansas US Patent | Assay Description To perform kinetic analyses of the binding of phosphonate derivatives to ABAD, the BIACORE 3000 instrument (based on surface plasmon resonance [SPR] ... | US Patent US9738668 (2017) BindingDB Entry DOI: 10.7270/Q22Z17NP | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amyloid beta-binding alcohol dehydrogenase (Homo sapiens (Human)) | BDBM232927 (US9346839, 8 | US9738668, Compound 8) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 291 | n/a | n/a | n/a | n/a | n/a |
University of Kansas US Patent | Assay Description To perform kinetic analyses of the binding of phosphonate derivatives to ABAD, the BIACORE 3000 instrument (based on surface plasmon resonance [SPR] ... | US Patent US9738668 (2017) BindingDB Entry DOI: 10.7270/Q22Z17NP | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amyloid beta-binding alcohol dehydrogenase (Homo sapiens (Human)) | BDBM232923 (US9346839, 4 | US9738668, Compound 4) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 496 | n/a | n/a | n/a | n/a | n/a |
University of Kansas US Patent | Assay Description To perform kinetic analyses of the binding of phosphonate derivatives to ABAD, the BIACORE 3000 instrument (based on surface plasmon resonance [SPR] ... | US Patent US9738668 (2017) BindingDB Entry DOI: 10.7270/Q22Z17NP | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
