Reaction Details |
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Target | Amyloid beta-binding alcohol dehydrogenase |
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Ligand | BDBM232924 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Assay of ABAD Enzymatic Activity |
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IC50 | 335000±n/a nM |
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Citation | Yan, S; Valasani, KR Phosphonate derivatives and methods of use thereof in the treatment of Alzheimer's disease US Patent US9738668 Publication Date 8/22/2017 |
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More Info.: | Get all data from this article, Assay Method |
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Amyloid beta-binding alcohol dehydrogenase |
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Name: | Amyloid beta-binding alcohol dehydrogenase |
Synonyms: | Amyloid beta-binding alcohol dehydrogenase (ABAD) |
Type: | Enzyme |
Mol. Mass.: | 938.17 |
Organism: | Homo sapiens (Human) |
Description: | Q2L8D9 |
Residue: | 9 |
Sequence: | |
BDBM232924 |
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n/a |
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Name | BDBM232924 |
Synonyms: | US9346839, 5 | US9738668, Compound 5 |
Type | Small organic molecule |
Emp. Form. | C18H18FN2O6PS |
Mol. Mass. | 440.382 |
SMILES | COC(=O)c1cc(ccc1O)[C@H](Nc1nc2cc(F)ccc2s1)P(=O)(OC)OC |r| |
Structure |
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