Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Receptor activity-modifying protein 1 (Homo sapiens (Human)) | BDBM391716 (N-[(2R)-3-(7-methyl-1H- | US10300056, Example 1 | ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Heptares Therapeutics Limited US Patent | Assay Description Radioligand binding assay. Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended i... | US Patent US10888561 (2021) BindingDB Entry DOI: 10.7270/Q28S4T1X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor activity-modifying protein 1 (Homo sapiens (Human)) | BDBM391727 (N-[(2R)-1-({(2S)-3-{1-[2- | US10300056, Example 12...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0250 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Heptares Therapeutics Limited US Patent | Assay Description Radioligand binding assay. Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended i... | US Patent US10888561 (2021) BindingDB Entry DOI: 10.7270/Q28S4T1X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor activity-modifying protein 1 (Homo sapiens (Human)) | BDBM391726 (N-[(2R)-3-(7-methyl-1H- | US10300056, Example 11 |...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | US Patent | 0.0320 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Heptares Therapeutics Limited US Patent | Assay Description Radioligand binding assay. Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended i... | US Patent US10888561 (2021) BindingDB Entry DOI: 10.7270/Q28S4T1X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor activity-modifying protein 1 (Homo sapiens (Human)) | BDBM391723 (3,5-dibromo-Nalpha-{[4-(2- | US10300056, Example 8...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Heptares Therapeutics Limited US Patent | Assay Description Radioligand binding assay. Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended i... | US Patent US10888561 (2021) BindingDB Entry DOI: 10.7270/Q28S4T1X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor activity-modifying protein 1 (Homo sapiens (Human)) | BDBM391719 (N-[(2R)-3-(7-methyl-1H- | US10300056, Example 4 | ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Heptares Therapeutics Limited US Patent | Assay Description Radioligand binding assay. Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended i... | US Patent US10888561 (2021) BindingDB Entry DOI: 10.7270/Q28S4T1X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor activity-modifying protein 1 (Homo sapiens (Human)) | BDBM391722 (N-[(2R)-1-({(2S)-3-(1- | US10300056, Example 7 | U...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Heptares Therapeutics Limited US Patent | Assay Description Radioligand binding assay. Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended i... | US Patent US10888561 (2021) BindingDB Entry DOI: 10.7270/Q28S4T1X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor activity-modifying protein 1 (Homo sapiens (Human)) | BDBM391725 (N-[(2R)-3-(7-methyl-1H- | US10300056, Example 10 |...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0630 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Heptares Therapeutics Limited US Patent | Assay Description Radioligand binding assay. Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended i... | US Patent US10888561 (2021) BindingDB Entry DOI: 10.7270/Q28S4T1X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor activity-modifying protein 1 (Homo sapiens (Human)) | BDBM391720 (3,5-dibromo-Nalpha-{[4-(2- | US10300056, Example 5...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0630 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Heptares Therapeutics Limited US Patent | Assay Description Radioligand binding assay. Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended i... | US Patent US10888561 (2021) BindingDB Entry DOI: 10.7270/Q28S4T1X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor activity-modifying protein 1 (Homo sapiens (Human)) | BDBM391724 (3,5-dibromo-Nalpha-{[4-(2- | US10300056, Example 9...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0790 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Heptares Therapeutics Limited US Patent | Assay Description Radioligand binding assay. Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended i... | US Patent US10888561 (2021) BindingDB Entry DOI: 10.7270/Q28S4T1X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor activity-modifying protein 1 (Homo sapiens (Human)) | BDBM391729 (3,5-dibromo-Nalpha-[(2'-oxo- | US10300056, Example...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0790 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Heptares Therapeutics Limited US Patent | Assay Description Radioligand binding assay. Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended i... | US Patent US10888561 (2021) BindingDB Entry DOI: 10.7270/Q28S4T1X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor activity-modifying protein 1 (Homo sapiens (Human)) | BDBM391718 (N-[(2R)-3-(7-methyl-1H- | US10300056, Example 3 | ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0790 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Heptares Therapeutics Limited US Patent | Assay Description Radioligand binding assay. Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended i... | US Patent US10888561 (2021) BindingDB Entry DOI: 10.7270/Q28S4T1X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor activity-modifying protein 1 (Homo sapiens (Human)) | BDBM391717 (US10300056, Example 2 | US10888561, Example 2 | te...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Heptares Therapeutics Limited US Patent | Assay Description Radioligand binding assay. Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended i... | US Patent US10888561 (2021) BindingDB Entry DOI: 10.7270/Q28S4T1X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor activity-modifying protein 1 (Homo sapiens (Human)) | BDBM391721 (N-[(2R)-3-(7-methyl-1H- | US10300056, Example 6 | ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Heptares Therapeutics Limited US Patent | Assay Description Radioligand binding assay. Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended i... | US Patent US10888561 (2021) BindingDB Entry DOI: 10.7270/Q28S4T1X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor activity-modifying protein 1 (Homo sapiens (Human)) | BDBM391728 (3-(4-{(2S)-2-{[(2R)-3-(7- | US10300056, Example 13...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | US Patent | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Heptares Therapeutics Limited US Patent | Assay Description Radioligand binding assay. Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended i... | US Patent US10888561 (2021) BindingDB Entry DOI: 10.7270/Q28S4T1X | |||||||||||
More data for this Ligand-Target Pair |