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Patent code US8921389

Compile Data Set for Download or QSAR

Found 217 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Egl nine homolog 1


(Homo sapiens (Human))		BDBM141558
PNG
(US8921389, 14 | US9695170 42)
Show SMILES OC(=O)CNC(=O)c1nc(C#N)c2n(Cc3ccccc3)c(=O)c(cc2c1O)-c1ccccc1
Show InChI InChI=1S/C25H18N4O5/c26-12-19-22-18(23(32)21(28-19)24(33)27-13-20(30)31)11-17(16-9-5-2-6-10-16)25(34)29(22)14-15-7-3-1-4-8-15/h1-11,32H,13-14H2,(H,27,33)(H,30,31)
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n/an/a 60n/an/an/an/a7.4n/a



Fibrogen, Inc.

US Patent


Assay Description
Ketoglutaric acid alpha -[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources,...

US Patent US8921389 (2014)


BindingDB Entry DOI: 10.7270/Q20G3HV0
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM141561
PNG
(US8921389, 17 | US9695170 17)
Show SMILES OC(=O)CNC(=O)c1nc(C#N)c2n(Cc3ccccc3)c(=O)c(Cc3ccccc3)cc2c1O
Show InChI InChI=1S/C26H20N4O5/c27-13-20-23-19(24(33)22(29-20)25(34)28-14-21(31)32)12-18(11-16-7-3-1-4-8-16)26(35)30(23)15-17-9-5-2-6-10-17/h1-10,12,33H,11,14-15H2,(H,28,34)(H,31,32)
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n/an/a 90n/an/an/an/a7.4n/a



Fibrogen, Inc.

US Patent


Assay Description
Ketoglutaric acid alpha -[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources,...

US Patent US8921389 (2014)


BindingDB Entry DOI: 10.7270/Q20G3HV0
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM141550
PNG
(US8921389, 6 | US9695170 6)
Show SMILES Cc1cc2c(O)c(nc(C#N)c2n(Cc2ccccc2)c1=O)C(=O)NCC(O)=O
Show InChI InChI=1S/C20H16N4O5/c1-11-7-13-17(24(20(11)29)10-12-5-3-2-4-6-12)14(8-21)23-16(18(13)27)19(28)22-9-15(25)26/h2-7,27H,9-10H2,1H3,(H,22,28)(H,25,26)
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n/an/a 90n/an/an/an/a7.4n/a



Fibrogen, Inc.

US Patent


Assay Description
Ketoglutaric acid alpha -[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources,...

US Patent US8921389 (2014)


BindingDB Entry DOI: 10.7270/Q20G3HV0
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM141591
PNG
(US8921389, 47 | US9695170 47)
Show SMILES OC(=O)CNC(=O)c1nc(C#N)c2c(ccn(Cc3ccccc3)c2=O)c1O
Show InChI InChI=1S/C19H14N4O5/c20-8-13-15-12(17(26)16(22-13)18(27)21-9-14(24)25)6-7-23(19(15)28)10-11-4-2-1-3-5-11/h1-7,26H,9-10H2,(H,21,27)(H,24,25)
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n/an/a 100n/an/an/an/a7.4n/a



Fibrogen, Inc.

US Patent


Assay Description
Ketoglutaric acid alpha -[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources,...

US Patent US8921389 (2014)


BindingDB Entry DOI: 10.7270/Q20G3HV0
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM141571
PNG
(US8921389, 27 | US9695170 27)
Show SMILES OC(=O)CCNC(=O)c1ncc2c(ccn(Cc3ccccc3)c2=O)c1O
Show InChI InChI=1S/C19H17N3O5/c23-15(24)6-8-20-18(26)16-17(25)13-7-9-22(19(27)14(13)10-21-16)11-12-4-2-1-3-5-12/h1-5,7,9-10,25H,6,8,11H2,(H,20,26)(H,23,24)
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n/an/a 180n/an/an/an/a7.4n/a



Fibrogen, Inc.

US Patent


Assay Description
Ketoglutaric acid alpha -[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources,...

US Patent US8921389 (2014)


BindingDB Entry DOI: 10.7270/Q20G3HV0
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM141575
PNG
(US8921389, 31 | US9695170 31)
Show SMILES Oc1c(ncc2c1ccn(Cc1ccccc1)c2=O)C(=O)NCc1ccncc1
Show InChI InChI=1S/C22H18N4O3/c27-20-17-8-11-26(14-16-4-2-1-3-5-16)22(29)18(17)13-24-19(20)21(28)25-12-15-6-9-23-10-7-15/h1-11,13,27H,12,14H2,(H,25,28)
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n/an/a 190n/an/an/an/a7.4n/a



Fibrogen, Inc.

US Patent


Assay Description
Ketoglutaric acid alpha -[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources,...

US Patent US8921389 (2014)


BindingDB Entry DOI: 10.7270/Q20G3HV0
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM141560
PNG
(US8921389, 16)
Show SMILES OC(=O)CNC(=O)c1nc(-c2cccnc2)c2n(Cc3ccccc3)c(=O)c(cc2c1O)-c1ccccc1
Show InChI InChI=1S/C29H22N4O5/c34-23(35)16-31-28(37)25-27(36)22-14-21(19-10-5-2-6-11-19)29(38)33(17-18-8-3-1-4-9-18)26(22)24(32-25)20-12-7-13-30-15-20/h1-15,36H,16-17H2,(H,31,37)(H,34,35)
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n/an/a 210n/an/an/an/a7.4n/a



Fibrogen, Inc.

US Patent


Assay Description
Ketoglutaric acid alpha -[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources,...

US Patent US8921389 (2014)


BindingDB Entry DOI: 10.7270/Q20G3HV0
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM141570
PNG
(US8921389, 26 | US9695170 26)
Show SMILES OC(=O)CNC(=O)c1ncc2c(ccn(Cc3ccccc3)c2=O)c1O
Show InChI InChI=1S/C18H15N3O5/c22-14(23)9-20-17(25)15-16(24)12-6-7-21(18(26)13(12)8-19-15)10-11-4-2-1-3-5-11/h1-8,24H,9-10H2,(H,20,25)(H,22,23)
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n/an/a 220n/an/an/an/a7.4n/a



Fibrogen, Inc.

US Patent


Assay Description
Ketoglutaric acid alpha -[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources,...

US Patent US8921389 (2014)


BindingDB Entry DOI: 10.7270/Q20G3HV0
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM141553
PNG
(US8921389, 9 | US9695170 9)
Show SMILES OC(=O)CNC(=O)c1nc(C#N)c2N(Cc3ccccc3)C(=O)CCc2c1O
Show InChI InChI=1S/C19H16N4O5/c20-8-13-17-12(18(27)16(22-13)19(28)21-9-15(25)26)6-7-14(24)23(17)10-11-4-2-1-3-5-11/h1-5,27H,6-7,9-10H2,(H,21,28)(H,25,26)
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n/an/a 220n/an/an/an/a7.4n/a



Fibrogen, Inc.

US Patent


Assay Description
Ketoglutaric acid alpha -[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources,...

US Patent US8921389 (2014)


BindingDB Entry DOI: 10.7270/Q20G3HV0
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM141551
PNG
(US8921389, 7 | US9695170 7)
Show SMILES OC(=O)CNC(=O)c1ncc2n(Cc3ccccc3)c(=O)ccc2c1O
Show InChI InChI=1S/C18H15N3O5/c22-14-7-6-12-13(21(14)10-11-4-2-1-3-5-11)8-19-16(17(12)25)18(26)20-9-15(23)24/h1-8,25H,9-10H2,(H,20,26)(H,23,24)
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n/an/a 220n/an/an/an/a7.4n/a



Fibrogen, Inc.

US Patent


Assay Description
Ketoglutaric acid alpha -[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources,...

US Patent US8921389 (2014)


BindingDB Entry DOI: 10.7270/Q20G3HV0
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM141556
PNG
(US8921389, 12 | US9695170 12)
Show SMILES Cc1nc(C(=O)NCC(O)=O)c(O)c2cc(-c3ccccc3)c(=O)n(Cc3ccccc3)c12
Show InChI InChI=1S/C25H21N3O5/c1-15-22-19(23(31)21(27-15)24(32)26-13-20(29)30)12-18(17-10-6-3-7-11-17)25(33)28(22)14-16-8-4-2-5-9-16/h2-12,31H,13-14H2,1H3,(H,26,32)(H,29,30)
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n/an/a 230n/an/an/an/a7.4n/a



Fibrogen, Inc.

US Patent


Assay Description
Ketoglutaric acid alpha -[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources,...

US Patent US8921389 (2014)


BindingDB Entry DOI: 10.7270/Q20G3HV0
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM141609
PNG
(US8921389, 65 | US9695170 65)
Show SMILES COc1ccc(Cn2ccc3c(O)c(ncc3c2=O)C(=O)NCCC(O)=O)c(OC)c1
Show InChI InChI=1S/C21H21N3O7/c1-30-13-4-3-12(16(9-13)31-2)11-24-8-6-14-15(21(24)29)10-23-18(19(14)27)20(28)22-7-5-17(25)26/h3-4,6,8-10,27H,5,7,11H2,1-2H3,(H,22,28)(H,25,26)
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n/an/a 230n/an/an/an/a7.4n/a



Fibrogen, Inc.

US Patent


Assay Description
Ketoglutaric acid alpha -[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources,...

US Patent US8921389 (2014)


BindingDB Entry DOI: 10.7270/Q20G3HV0
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM141547
PNG
(US8921389, 3 | US9695170 3)
Show SMILES OC(=O)CNC(=O)c1ncc2n(Cc3ccccc3)c(=O)c(Cc3ccccc3)cc2c1O
Show InChI InChI=1S/C25H21N3O5/c29-21(30)14-27-24(32)22-23(31)19-12-18(11-16-7-3-1-4-8-16)25(33)28(20(19)13-26-22)15-17-9-5-2-6-10-17/h1-10,12-13,31H,11,14-15H2,(H,27,32)(H,29,30)
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n/an/a 230n/an/an/an/a7.4n/a



Fibrogen, Inc.

US Patent


Assay Description
Ketoglutaric acid alpha -[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources,...

US Patent US8921389 (2014)


BindingDB Entry DOI: 10.7270/Q20G3HV0
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM141548
PNG
(US8921389, 4 | US9695170 83)
Show SMILES OC(=O)CNC(=O)c1ncc2n(Cc3ccccc3)c(=O)c(cc2c1O)-c1ccccc1
Show InChI InChI=1S/C24H19N3O5/c28-20(29)13-26-23(31)21-22(30)18-11-17(16-9-5-2-6-10-16)24(32)27(19(18)12-25-21)14-15-7-3-1-4-8-15/h1-12,30H,13-14H2,(H,26,31)(H,28,29)
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n/an/a 260n/an/an/an/a7.4n/a



Fibrogen, Inc.

US Patent


Assay Description
Ketoglutaric acid alpha -[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources,...

US Patent US8921389 (2014)


BindingDB Entry DOI: 10.7270/Q20G3HV0
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM141608
PNG
(US8921389, 64 | US9695170 64)
Show SMILES COc1ccc(Cn2ccc3c(O)c(ncc3c2=O)C(=O)NCC(O)=O)c(OC)c1
Show InChI InChI=1S/C20H19N3O7/c1-29-12-4-3-11(15(7-12)30-2)10-23-6-5-13-14(20(23)28)8-21-17(18(13)26)19(27)22-9-16(24)25/h3-8,26H,9-10H2,1-2H3,(H,22,27)(H,24,25)
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n/an/a 280n/an/an/an/a7.4n/a



Fibrogen, Inc.

US Patent


Assay Description
Ketoglutaric acid alpha -[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources,...

US Patent US8921389 (2014)


BindingDB Entry DOI: 10.7270/Q20G3HV0
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM141630
PNG
(US8921389, 86)
Show SMILES Oc1c(ncc2c1ccn(Cc1ccccc1)c2=O)C(=O)NCc1nnn[nH]1
Show InChI InChI=1S/C18H15N7O3/c26-16-12-6-7-25(10-11-4-2-1-3-5-11)18(28)13(12)8-19-15(16)17(27)20-9-14-21-23-24-22-14/h1-8,26H,9-10H2,(H,20,27)(H,21,22,23,24)
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n/an/a 290n/an/an/an/a7.4n/a



Fibrogen, Inc.

US Patent


Assay Description
Ketoglutaric acid alpha -[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources,...

US Patent US8921389 (2014)


BindingDB Entry DOI: 10.7270/Q20G3HV0
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM141557
PNG
(US8921389, 13 | US9695170 16)
Show SMILES OC(=O)CNC(=O)c1nc(-c2ccccc2)c2n(Cc3ccccc3)c(=O)c(cc2c1O)-c1ccccc1
Show InChI InChI=1S/C30H23N3O5/c34-24(35)17-31-29(37)26-28(36)23-16-22(20-12-6-2-7-13-20)30(38)33(18-19-10-4-1-5-11-19)27(23)25(32-26)21-14-8-3-9-15-21/h1-16,36H,17-18H2,(H,31,37)(H,34,35)
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n/an/a 300n/an/an/an/a7.4n/a



Fibrogen, Inc.

US Patent


Assay Description
Ketoglutaric acid alpha -[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources,...

US Patent US8921389 (2014)


BindingDB Entry DOI: 10.7270/Q20G3HV0
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM141612
PNG
(US8921389, 68)
Show SMILES COc1ccc(CN2CCc3c(O)c(ncc3C2=O)C(=O)NCCC(O)=O)c(OC)c1
Show InChI InChI=1S/C21H23N3O7/c1-30-13-4-3-12(16(9-13)31-2)11-24-8-6-14-15(21(24)29)10-23-18(19(14)27)20(28)22-7-5-17(25)26/h3-4,9-10,27H,5-8,11H2,1-2H3,(H,22,28)(H,25,26)
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n/an/a 320n/an/an/an/a7.4n/a



Fibrogen, Inc.

US Patent


Assay Description
Ketoglutaric acid alpha -[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources,...

US Patent US8921389 (2014)


BindingDB Entry DOI: 10.7270/Q20G3HV0
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM141658
PNG
(US8921389, 115 | US9695170 115)
Show SMILES CN(CCNC(=O)c1ncc2c(ccn(Cc3ccccc3)c2=O)c1O)C=O
Show InChI InChI=1S/C20H20N4O4/c1-23(13-25)10-8-21-19(27)17-18(26)15-7-9-24(20(28)16(15)11-22-17)12-14-5-3-2-4-6-14/h2-7,9,11,13,26H,8,10,12H2,1H3,(H,21,27)
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n/an/a 350n/an/an/an/a7.4n/a



Fibrogen, Inc.

US Patent


Assay Description
Ketoglutaric acid alpha -[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources,...

US Patent US8921389 (2014)


BindingDB Entry DOI: 10.7270/Q20G3HV0
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM141589
PNG
(US8921389, 45 | US9695170 45)
Show SMILES OC(=O)CNC(=O)c1nc(-c2cncc(F)c2)c2c(ccn(Cc3ccccc3)c2=O)c1O
Show InChI InChI=1S/C23H17FN4O5/c24-15-8-14(9-25-10-15)19-18-16(21(31)20(27-19)22(32)26-11-17(29)30)6-7-28(23(18)33)12-13-4-2-1-3-5-13/h1-10,31H,11-12H2,(H,26,32)(H,29,30)
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n/an/a 350n/an/an/an/a7.4n/a



Fibrogen, Inc.

US Patent


Assay Description
Ketoglutaric acid alpha -[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources,...

US Patent US8921389 (2014)


BindingDB Entry DOI: 10.7270/Q20G3HV0
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM141581
PNG
(US8921389, 37 | US9695170 37)
Show SMILES Oc1c(ncc2c1ccn(Cc1ccccc1)c2=O)C(=O)NC1CC1
Show InChI InChI=1S/C19H17N3O3/c23-17-14-8-9-22(11-12-4-2-1-3-5-12)19(25)15(14)10-20-16(17)18(24)21-13-6-7-13/h1-5,8-10,13,23H,6-7,11H2,(H,21,24)
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n/an/a 390n/an/an/an/a7.4n/a



Fibrogen, Inc.

US Patent


Assay Description
Ketoglutaric acid alpha -[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources,...

US Patent US8921389 (2014)


BindingDB Entry DOI: 10.7270/Q20G3HV0
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM141737
PNG
(US8921389, 196 | US9695170 196)
Show SMILES Oc1c(ncc2c1ccn(Cc1ccccc1)c2=O)C(=O)NCCCNC=O
Show InChI InChI=1S/C20H20N4O4/c25-13-21-8-4-9-22-19(27)17-18(26)15-7-10-24(20(28)16(15)11-23-17)12-14-5-2-1-3-6-14/h1-3,5-7,10-11,13,26H,4,8-9,12H2,(H,21,25)(H,22,27)
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n/an/a 400n/an/an/an/a7.4n/a



Fibrogen, Inc.

US Patent


Assay Description
Ketoglutaric acid alpha -[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources,...

US Patent US8921389 (2014)


BindingDB Entry DOI: 10.7270/Q20G3HV0
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM141555
PNG
(US8921389, 11 | US9695170 11)
Show SMILES OC(=O)CNC(=O)c1ncc2n(Cc3ccccc3)c(=O)c(CCc3ccccc3)cc2c1O
Show InChI InChI=1S/C26H23N3O5/c30-22(31)15-28-25(33)23-24(32)20-13-19(12-11-17-7-3-1-4-8-17)26(34)29(21(20)14-27-23)16-18-9-5-2-6-10-18/h1-10,13-14,32H,11-12,15-16H2,(H,28,33)(H,30,31)
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n/an/a 410n/an/an/an/a7.4n/a



Fibrogen, Inc.

US Patent


Assay Description
Ketoglutaric acid alpha -[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources,...

US Patent US8921389 (2014)


BindingDB Entry DOI: 10.7270/Q20G3HV0
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM141601
PNG
(US8921389, 57)
Show SMILES C[C@H](NC(=O)c1nc(C#N)c2c(ccn(Cc3ccccc3)c2=O)c1O)C(O)=O
Show InChI InChI=1S/C20H16N4O5/c1-11(20(28)29)22-18(26)16-17(25)13-7-8-24(10-12-5-3-2-4-6-12)19(27)15(13)14(9-21)23-16/h2-8,11,25H,10H2,1H3,(H,22,26)(H,28,29)/t11-/m0/s1
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n/an/a 420n/an/an/an/a7.4n/a



Fibrogen, Inc.

US Patent


Assay Description
Ketoglutaric acid alpha -[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources,...

US Patent US8921389 (2014)


BindingDB Entry DOI: 10.7270/Q20G3HV0
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM141611
PNG
(US8921389, 67)
Show SMILES COc1ccc(CN2CCc3c(O)c(ncc3C2=O)C(=O)NCC(O)=O)c(OC)c1
Show InChI InChI=1S/C20H21N3O7/c1-29-12-4-3-11(15(7-12)30-2)10-23-6-5-13-14(20(23)28)8-21-17(18(13)26)19(27)22-9-16(24)25/h3-4,7-8,26H,5-6,9-10H2,1-2H3,(H,22,27)(H,24,25)
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n/an/a 440n/an/an/an/a7.4n/a



Fibrogen, Inc.

US Patent


Assay Description
Ketoglutaric acid alpha -[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources,...

US Patent US8921389 (2014)


BindingDB Entry DOI: 10.7270/Q20G3HV0
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM141659
PNG
(US8921389, 116 | US9695170 116)
Show SMILES CN(CCNC(=O)c1ncc2c(ccn(Cc3ccccc3)c2=O)c1O)C(C)=O
Show InChI InChI=1S/C21H22N4O4/c1-14(26)24(2)11-9-22-20(28)18-19(27)16-8-10-25(21(29)17(16)12-23-18)13-15-6-4-3-5-7-15/h3-8,10,12,27H,9,11,13H2,1-2H3,(H,22,28)
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n/an/a 440n/an/an/an/a7.4n/a



Fibrogen, Inc.

US Patent


Assay Description
Ketoglutaric acid alpha -[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources,...

US Patent US8921389 (2014)


BindingDB Entry DOI: 10.7270/Q20G3HV0
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM141607
PNG
(US8921389, 63)
Show SMILES CNC(=O)c1ncc2c(ccn(Cc3ccc(OC)cc3OC)c2=O)c1O
Show InChI InChI=1S/C19H19N3O5/c1-20-18(24)16-17(23)13-6-7-22(19(25)14(13)9-21-16)10-11-4-5-12(26-2)8-15(11)27-3/h4-9,23H,10H2,1-3H3,(H,20,24)
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n/an/a 500n/an/an/an/a7.4n/a



Fibrogen, Inc.

US Patent


Assay Description
Ketoglutaric acid alpha -[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources,...

US Patent US8921389 (2014)


BindingDB Entry DOI: 10.7270/Q20G3HV0
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM141554
PNG
(US8921389, 10 | US9695170 10)
Show SMILES Cc1cc2c(O)c(nc(-c3cccnc3)c2n(Cc2ccccc2)c1=O)C(=O)NCC(O)=O
Show InChI InChI=1S/C24H20N4O5/c1-14-10-17-21(28(24(14)33)13-15-6-3-2-4-7-15)19(16-8-5-9-25-11-16)27-20(22(17)31)23(32)26-12-18(29)30/h2-11,31H,12-13H2,1H3,(H,26,32)(H,29,30)
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n/an/a 520n/an/an/an/a7.4n/a



Fibrogen, Inc.

US Patent


Assay Description
Ketoglutaric acid alpha -[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources,...

US Patent US8921389 (2014)


BindingDB Entry DOI: 10.7270/Q20G3HV0
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM141565
PNG
(US8921389, 21)
Show SMILES OC(=O)CNC(=O)c1nc(-c2cccnc2)c2n(Cc3ccccc3)c(=O)c(Cc3ccccc3)cc2c1O
Show InChI InChI=1S/C30H24N4O5/c35-24(36)17-32-29(38)26-28(37)23-15-22(14-19-8-3-1-4-9-19)30(39)34(18-20-10-5-2-6-11-20)27(23)25(33-26)21-12-7-13-31-16-21/h1-13,15-16,37H,14,17-18H2,(H,32,38)(H,35,36)
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n/an/a 610n/an/an/an/a7.4n/a



Fibrogen, Inc.

US Patent


Assay Description
Ketoglutaric acid alpha -[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources,...

US Patent US8921389 (2014)


BindingDB Entry DOI: 10.7270/Q20G3HV0
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM141636
PNG
(US8921389, 92)
Show SMILES CC(=O)NCCNC(=O)c1ncc2c(ccn(Cc3ccccc3)c2=O)c1O
Show InChI InChI=1S/C20H20N4O4/c1-13(25)21-8-9-22-19(27)17-18(26)15-7-10-24(20(28)16(15)11-23-17)12-14-5-3-2-4-6-14/h2-7,10-11,26H,8-9,12H2,1H3,(H,21,25)(H,22,27)
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n/an/a 610n/an/an/an/a7.4n/a



Fibrogen, Inc.

US Patent


Assay Description
Ketoglutaric acid alpha -[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources,...

US Patent US8921389 (2014)


BindingDB Entry DOI: 10.7270/Q20G3HV0
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM141546
PNG
(US8921389, 2 | US9695170 2)
Show SMILES Cc1cc2c(O)c(ncc2n(Cc2ccccc2)c1=O)C(=O)NCC(O)=O
Show InChI InChI=1S/C19H17N3O5/c1-11-7-13-14(22(19(11)27)10-12-5-3-2-4-6-12)8-20-16(17(13)25)18(26)21-9-15(23)24/h2-8,25H,9-10H2,1H3,(H,21,26)(H,23,24)
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n/an/a 630n/an/an/an/a7.4n/a



Fibrogen, Inc.

US Patent


Assay Description
Ketoglutaric acid alpha -[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources,...

US Patent US8921389 (2014)


BindingDB Entry DOI: 10.7270/Q20G3HV0
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM141580
PNG
(US8921389, 36 | US9695170 36)
Show SMILES CCCNC(=O)c1ncc2c(ccn(Cc3ccccc3)c2=O)c1O
Show InChI InChI=1S/C19H19N3O3/c1-2-9-20-18(24)16-17(23)14-8-10-22(19(25)15(14)11-21-16)12-13-6-4-3-5-7-13/h3-8,10-11,23H,2,9,12H2,1H3,(H,20,24)
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n/an/a 650n/an/an/an/a7.4n/a



Fibrogen, Inc.

US Patent


Assay Description
Ketoglutaric acid alpha -[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources,...

US Patent US8921389 (2014)


BindingDB Entry DOI: 10.7270/Q20G3HV0
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM141574
PNG
(US8921389, 30 | US9695170 30)
Show SMILES OC(=O)CCCCNC(=O)c1ncc2c(ccn(Cc3ccccc3)c2=O)c1O
Show InChI InChI=1S/C21H21N3O5/c25-17(26)8-4-5-10-22-20(28)18-19(27)15-9-11-24(21(29)16(15)12-23-18)13-14-6-2-1-3-7-14/h1-3,6-7,9,11-12,27H,4-5,8,10,13H2,(H,22,28)(H,25,26)
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n/an/a 660n/an/an/an/a7.4n/a



Fibrogen, Inc.

US Patent


Assay Description
Ketoglutaric acid alpha -[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources,...

US Patent US8921389 (2014)


BindingDB Entry DOI: 10.7270/Q20G3HV0
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM141635
PNG
(US8921389, 91)
Show SMILES Oc1c(ncc2c1ccn(Cc1ccccc1)c2=O)C(=O)NCCNC(=O)C(F)(F)F
Show InChI InChI=1S/C20H17F3N4O4/c21-20(22,23)19(31)25-8-7-24-17(29)15-16(28)13-6-9-27(18(30)14(13)10-26-15)11-12-4-2-1-3-5-12/h1-6,9-10,28H,7-8,11H2,(H,24,29)(H,25,31)
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n/an/a 690n/an/an/an/a7.4n/a



Fibrogen, Inc.

US Patent


Assay Description
Ketoglutaric acid alpha -[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources,...

US Patent US8921389 (2014)


BindingDB Entry DOI: 10.7270/Q20G3HV0
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM141573
PNG
(US8921389, 29 | US9695170 29)
Show SMILES OC(=O)CCCNC(=O)c1ncc2c(ccn(Cc3ccccc3)c2=O)c1O
Show InChI InChI=1S/C20H19N3O5/c24-16(25)7-4-9-21-19(27)17-18(26)14-8-10-23(20(28)15(14)11-22-17)12-13-5-2-1-3-6-13/h1-3,5-6,8,10-11,26H,4,7,9,12H2,(H,21,27)(H,24,25)
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n/an/a 760n/an/an/an/a7.4n/a



Fibrogen, Inc.

US Patent


Assay Description
Ketoglutaric acid alpha -[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources,...

US Patent US8921389 (2014)


BindingDB Entry DOI: 10.7270/Q20G3HV0
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM141576
PNG
(US8921389, 32 | US9695170 34)
Show SMILES CNC(=O)c1ncc2c(ccn(Cc3ccccc3)c2=O)c1O
Show InChI InChI=1S/C17H15N3O3/c1-18-16(22)14-15(21)12-7-8-20(17(23)13(12)9-19-14)10-11-5-3-2-4-6-11/h2-9,21H,10H2,1H3,(H,18,22)
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n/an/a 800n/an/an/an/a7.4n/a



Fibrogen, Inc.

US Patent


Assay Description
Ketoglutaric acid alpha -[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources,...

US Patent US8921389 (2014)


BindingDB Entry DOI: 10.7270/Q20G3HV0
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM141738
PNG
(US8921389, 197 | US9695170 197)
Show SMILES CC(=O)NCCCNC(=O)c1ncc2c(ccn(Cc3ccccc3)c2=O)c1O
Show InChI InChI=1S/C21H22N4O4/c1-14(26)22-9-5-10-23-20(28)18-19(27)16-8-11-25(21(29)17(16)12-24-18)13-15-6-3-2-4-7-15/h2-4,6-8,11-12,27H,5,9-10,13H2,1H3,(H,22,26)(H,23,28)
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n/an/a 800n/an/an/an/a7.4n/a



Fibrogen, Inc.

US Patent


Assay Description
Ketoglutaric acid alpha -[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources,...

US Patent US8921389 (2014)


BindingDB Entry DOI: 10.7270/Q20G3HV0
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM141640
PNG
(US8921389, 97)
Show SMILES CN(CCNC(=O)c1ncc2c(ccn(Cc3ccccc3)c2=O)c1O)C(=O)C(F)(F)F
Show InChI InChI=1S/C21H19F3N4O4/c1-27(20(32)21(22,23)24)10-8-25-18(30)16-17(29)14-7-9-28(19(31)15(14)11-26-16)12-13-5-3-2-4-6-13/h2-7,9,11,29H,8,10,12H2,1H3,(H,25,30)
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n/an/a 900n/an/an/an/a7.4n/a



Fibrogen, Inc.

US Patent


Assay Description
Ketoglutaric acid alpha -[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources,...

US Patent US8921389 (2014)


BindingDB Entry DOI: 10.7270/Q20G3HV0
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM141549
PNG
(US8921389, 5 | US9695170 5)
Show SMILES Cc1cc2c(O)c(nc(C)c2n(Cc2ccccc2)c1=O)C(=O)NCC(O)=O
Show InChI InChI=1S/C20H19N3O5/c1-11-8-14-17(23(20(11)28)10-13-6-4-3-5-7-13)12(2)22-16(18(14)26)19(27)21-9-15(24)25/h3-8,26H,9-10H2,1-2H3,(H,21,27)(H,24,25)
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n/an/a 930n/an/an/an/a7.4n/a



Fibrogen, Inc.

US Patent


Assay Description
Ketoglutaric acid alpha -[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources,...

US Patent US8921389 (2014)


BindingDB Entry DOI: 10.7270/Q20G3HV0
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM141629
PNG
(US8921389, 85)
Show SMILES OC(=O)COCCNC(=O)c1ncc2c(ccn(Cc3ccccc3)c2=O)c1O
Show InChI InChI=1S/C20H19N3O6/c24-16(25)12-29-9-7-21-19(27)17-18(26)14-6-8-23(20(28)15(14)10-22-17)11-13-4-2-1-3-5-13/h1-6,8,10,26H,7,9,11-12H2,(H,21,27)(H,24,25)
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n/an/a 1.00E+3n/an/an/an/a7.4n/a



Fibrogen, Inc.

US Patent


Assay Description
Ketoglutaric acid alpha -[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources,...

US Patent US8921389 (2014)


BindingDB Entry DOI: 10.7270/Q20G3HV0
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM141634
PNG
(US8921389, 90 | US9695170 90)
Show SMILES NS(=O)(=O)CCNC(=O)c1ncc2c(ccn(Cc3ccccc3)c2=O)c1O
Show InChI InChI=1S/C18H18N4O5S/c19-28(26,27)9-7-20-17(24)15-16(23)13-6-8-22(18(25)14(13)10-21-15)11-12-4-2-1-3-5-12/h1-6,8,10,23H,7,9,11H2,(H,20,24)(H2,19,26,27)
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n/an/a 1.00E+3n/an/an/an/a7.4n/a



Fibrogen, Inc.

US Patent


Assay Description
Ketoglutaric acid alpha -[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources,...

US Patent US8921389 (2014)


BindingDB Entry DOI: 10.7270/Q20G3HV0
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM141588
PNG
(US8921389, 44 | US9695170 44)
Show SMILES Cc1nc(C(=O)NCC(O)=O)c(O)c2ccn(Cc3ccccc3)c(=O)c12
Show InChI InChI=1S/C19H17N3O5/c1-11-15-13(17(25)16(21-11)18(26)20-9-14(23)24)7-8-22(19(15)27)10-12-5-3-2-4-6-12/h2-8,25H,9-10H2,1H3,(H,20,26)(H,23,24)
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n/an/a 1.10E+3n/an/an/an/a7.4n/a



Fibrogen, Inc.

US Patent


Assay Description
Ketoglutaric acid alpha -[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources,...

US Patent US8921389 (2014)


BindingDB Entry DOI: 10.7270/Q20G3HV0
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM141590
PNG
(US8921389, 46 | US9695170 46)
Show SMILES OC(=O)CNC(=O)c1nc(-c2ccccc2)c2c(ccn(Cc3ccccc3)c2=O)c1O
Show InChI InChI=1S/C24H19N3O5/c28-18(29)13-25-23(31)21-22(30)17-11-12-27(14-15-7-3-1-4-8-15)24(32)19(17)20(26-21)16-9-5-2-6-10-16/h1-12,30H,13-14H2,(H,25,31)(H,28,29)
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n/an/a 1.40E+3n/an/an/an/a7.4n/a



Fibrogen, Inc.

US Patent


Assay Description
Ketoglutaric acid alpha -[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources,...

US Patent US8921389 (2014)


BindingDB Entry DOI: 10.7270/Q20G3HV0
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM141647
PNG
(US8921389, 104 | US9695170 104)
Show SMILES NC(=O)NCCCNC(=O)c1ncc2c(ccn(Cc3ccccc3)c2=O)c1O
Show InChI InChI=1S/C20H21N5O4/c21-20(29)23-9-4-8-22-18(27)16-17(26)14-7-10-25(19(28)15(14)11-24-16)12-13-5-2-1-3-6-13/h1-3,5-7,10-11,26H,4,8-9,12H2,(H,22,27)(H3,21,23,29)
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n/an/a 1.50E+3n/an/an/an/a7.4n/a



Fibrogen, Inc.

US Patent


Assay Description
Ketoglutaric acid alpha -[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources,...

US Patent US8921389 (2014)


BindingDB Entry DOI: 10.7270/Q20G3HV0
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM141572
PNG
(US8921389, 28)
Show SMILES CC(C)(CNC(=O)c1ncc2c(ccn(Cc3ccccc3)c2=O)c1O)C(O)=O
Show InChI InChI=1S/C21H21N3O5/c1-21(2,20(28)29)12-23-18(26)16-17(25)14-8-9-24(19(27)15(14)10-22-16)11-13-6-4-3-5-7-13/h3-10,25H,11-12H2,1-2H3,(H,23,26)(H,28,29)
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n/an/a 1.70E+3n/an/an/an/a7.4n/a



Fibrogen, Inc.

US Patent


Assay Description
Ketoglutaric acid alpha -[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources,...

US Patent US8921389 (2014)


BindingDB Entry DOI: 10.7270/Q20G3HV0
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM141624
PNG
(US8921389, 80 | US9695170 80)
Show SMILES OC(=O)CNC(=O)c1nc(-c2cncc(F)c2)c2ccc(=O)n(Cc3ccccc3)c2c1O
Show InChI InChI=1S/C23H17FN4O5/c24-15-8-14(9-25-10-15)19-16-6-7-17(29)28(12-13-4-2-1-3-5-13)21(16)22(32)20(27-19)23(33)26-11-18(30)31/h1-10,32H,11-12H2,(H,26,33)(H,30,31)
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n/an/a 1.90E+3n/an/an/an/a7.4n/a



Fibrogen, Inc.

US Patent


Assay Description
Ketoglutaric acid alpha -[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources,...

US Patent US8921389 (2014)


BindingDB Entry DOI: 10.7270/Q20G3HV0
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM141644
PNG
(US8921389, 101 | US9695170 101)
Show SMILES CS(=O)(=O)NCCNC(=O)c1ncc2c(ccn(Cc3ccccc3)c2=O)c1O
Show InChI InChI=1S/C19H20N4O5S/c1-29(27,28)22-9-8-20-18(25)16-17(24)14-7-10-23(19(26)15(14)11-21-16)12-13-5-3-2-4-6-13/h2-7,10-11,22,24H,8-9,12H2,1H3,(H,20,25)
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n/an/a 1.90E+3n/an/an/an/a7.4n/a



Fibrogen, Inc.

US Patent


Assay Description
Ketoglutaric acid alpha -[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources,...

US Patent US8921389 (2014)


BindingDB Entry DOI: 10.7270/Q20G3HV0
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM141642
PNG
(US8921389, 99 | US9695170 99)
Show SMILES COC(=O)N(C)CCNC(=O)c1ncc2c(ccn(Cc3ccccc3)c2=O)c1O
Show InChI InChI=1S/C21H22N4O5/c1-24(21(29)30-2)11-9-22-19(27)17-18(26)15-8-10-25(20(28)16(15)12-23-17)13-14-6-4-3-5-7-14/h3-8,10,12,26H,9,11,13H2,1-2H3,(H,22,27)
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n/an/a 2.00E+3n/an/an/an/a7.4n/a



Fibrogen, Inc.

US Patent


Assay Description
Ketoglutaric acid alpha -[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources,...

US Patent US8921389 (2014)


BindingDB Entry DOI: 10.7270/Q20G3HV0
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM141545
PNG
(US8921389, 1 | US9695170 1)
Show SMILES OC(=O)CNC(=O)c1ncc2N(Cc3ccccc3)C(=O)CCc2c1O
Show InChI InChI=1S/C18H17N3O5/c22-14-7-6-12-13(21(14)10-11-4-2-1-3-5-11)8-19-16(17(12)25)18(26)20-9-15(23)24/h1-5,8,25H,6-7,9-10H2,(H,20,26)(H,23,24)
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n/an/a 2.10E+3n/an/an/an/a7.4n/a



Fibrogen, Inc.

US Patent


Assay Description
Ketoglutaric acid alpha -[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources,...

US Patent US8921389 (2014)


BindingDB Entry DOI: 10.7270/Q20G3HV0
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM141563
PNG
(US8921389, 19 | US9695170 19)
Show SMILES Cc1nc(C(=O)NCC(O)=O)c(O)c2cc(Cc3ccccc3)c(=O)n(Cc3ccccc3)c12
Show InChI InChI=1S/C26H23N3O5/c1-16-23-20(24(32)22(28-16)25(33)27-14-21(30)31)13-19(12-17-8-4-2-5-9-17)26(34)29(23)15-18-10-6-3-7-11-18/h2-11,13,32H,12,14-15H2,1H3,(H,27,33)(H,30,31)
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n/an/a 2.10E+3n/an/an/an/a7.4n/a



Fibrogen, Inc.

US Patent


Assay Description
Ketoglutaric acid alpha -[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources,...

US Patent US8921389 (2014)


BindingDB Entry DOI: 10.7270/Q20G3HV0
More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 217 total )  |  Next  |  Last  >>
* indicates data uncertainty>20%