BDBM141738 US8921389, 197::US9695170 197

SMILES: CC(=O)NCCCNC(=O)c1ncc2c(ccn(Cc3ccccc3)c2=O)c1O

InChI Key: InChIKey=GXRGTUSSVLKZDA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 141738   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Egl nine homolog 1 (Homo sapiens (Human))	BDBM141738 (US8921389, 197 | US9695170 197) Show SMILES CC(=O)NCCCNC(=O)c1ncc2c(ccn(Cc3ccccc3)c2=O)c1O Show InChI InChI=1S/C21H22N4O4/c1-14(26)22-9-5-10-23-20(28)18-19(27)16-8-11-25(21(29)17(16)12-24-18)13-15-6-3-2-4-7-15/h2-4,6-8,11-12,27H,5,9-10,13H2,1H3,(H,22,26)(H,23,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	800	n/a	n/a	n/a	n/a	7.4	n/a
FibroGen, Inc. US Patent					Assay Description Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...				US Patent US9695170 (2017) BindingDB Entry DOI: 10.7270/Q2P55KN0
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Homo sapiens (Human))	BDBM141738 (US8921389, 197 | US9695170 197) Show SMILES CC(=O)NCCCNC(=O)c1ncc2c(ccn(Cc3ccccc3)c2=O)c1O Show InChI InChI=1S/C21H22N4O4/c1-14(26)22-9-5-10-23-20(28)18-19(27)16-8-11-25(21(29)17(16)12-24-18)13-15-6-3-2-4-7-15/h2-4,6-8,11-12,27H,5,9-10,13H2,1H3,(H,22,26)(H,23,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	800	n/a	n/a	n/a	n/a	7.4	n/a
Fibrogen, Inc. US Patent					Assay Description Ketoglutaric acid alpha -[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources,...				US Patent US8921389 (2014) BindingDB Entry DOI: 10.7270/Q20G3HV0
					More data for this Ligand-Target Pair