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Patent code US8772495

Compile Data Set for Download or QSAR
Found 1 hit of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Arachidonate 5-lipoxygenase-activating protein


(Homo sapiens (Human))		BDBM125205
PNG
(US8772495, 2)
Show SMILES CCOc1ccc(cn1)-c1ccc(Cn2c(CC(C)(C)C([O-])=O)c(SC(C)(C)C)c3cc(OCc4ccc(C)cn4)ccc23)cc1
Show InChI InChI=1S/C38H43N3O4S/c1-8-44-34-18-14-28(22-40-34)27-12-10-26(11-13-27)23-41-32-17-16-30(45-24-29-15-9-25(2)21-39-29)19-31(32)35(46-37(3,4)5)33(41)20-38(6,7)36(42)43/h9-19,21-22H,8,20,23-24H2,1-7H3,(H,42,43)/p-1
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Similars
US Patent
n/an/a 2.90n/an/an/an/a7.4n/a



Panmira Pharmaceuticals, LLC

US Patent


Assay Description
Compound 2 was examined for its ability to bind human FLAP using a membrane-binding assay. The affinity of Compound 2 for human FLAP was assessed usi...

US Patent US8772495 (2014)


BindingDB Entry DOI: 10.7270/Q23F4N9F
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%