Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Polymerase acidic protein () | BDBM474361 ((S)-6-benzhydryl-11-hydroxy-3-(1H-pyrazol- 4-yl)-5...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/... | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polymerase acidic protein () | BDBM474354 ((S)-6-((S)-(3-fluorophenyl)(4- fluorophenyl)methyl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/... | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polymerase acidic protein () | BDBM474346 ((S)-6-benzhydryl-3-bromo-11-hydroxy-5H- imidazo[1,...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/... | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polymerase acidic protein () | BDBM474367 ((S)-6-((S)-(3-bromophenyl)(4- fluorophenyl)methyl)...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/... | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polymerase acidic protein () | BDBM474357 ((S)-6-((R)-(2-bromo-4-fluorophenyl)(4- fluoropheny...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/... | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polymerase acidic protein () | BDBM474343 ((S)-6-Benzhydryl-11-hydroxy-5H- imidazo[1,2-a]pyri...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/... | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polymerase acidic protein () | BDBM474344 ((S)-6-Benzhydryl-3-chloro-11-hydroxy-5,6- dihydro-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/... | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polymerase acidic protein () | BDBM474358 ((S)-6-((S)-(4-fluorophenyl)(o-tolyl)methyl)-11- hy...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/... | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polymerase acidic protein () | BDBM474350 ((S)-6-((S)-(4-fluorophenyl)(phenyl)methyl)- 11-hyd...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/... | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polymerase acidic protein () | BDBM474349 ((S)-6-((R)-(4-fluorophenyl)(phenyl)methyl)- 11-hyd...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/... | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polymerase acidic protein () | BDBM474355 ((S)-6-((S)-(4-chlorophenyl)(4- fluorophenyl)methyl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/... | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polymerase acidic protein () | BDBM474359 (3-((S)-(4-fluorophenyl)((S)-11-hydroxy-10- oxo-5,6...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/... | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polymerase acidic protein () | BDBM474351 ((S)-6-((R)-(4-fluorophenyl)(5-fluoropyridin-3- yl)...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/... | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polymerase acidic protein () | BDBM474364 ((S)-6-benzhydryl-3-(difluoromethyl)-11- hydroxy-5,...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/... | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polymerase acidic protein () | BDBM474347 ((S)-6-benzhydryl-3-cyclopropyl-11-hydroxy- 5H-imid...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/... | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polymerase acidic protein () | BDBM474366 (6-benzhydryl-5-ethyl-11-hydroxy-5,6-dihydro- 10H-i...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/... | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polymerase acidic protein () | BDBM474356 ((S)-6-((S)-(4-fluorophenyl)(m-tolyl)methyl)- 11-hy...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/... | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polymerase acidic protein () | BDBM474345 (6-benzhydryl-11-hydroxy-5,6-dihydro-10H- imidazo[1...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/... | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polymerase acidic protein () | BDBM474340 (6-Benzhydryl-11-hydroxy-5H- imidazo[2',1':3,4]pyra...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/... | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polymerase acidic protein () | BDBM474353 ((S)-6-(bis(3-fluorophenyl)methyl)-11- hydroxy-5,6-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/... | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polymerase acidic protein () | BDBM474360 (3-((R)-(3-fluorophenyl)((S)-11-hydroxy-10- oxo-5,6...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/... | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polymerase acidic protein () | BDBM474362 ((S)-6-benzhydryl-11-hydroxy-3-phenyl-5,6- dihydro-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/... | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polymerase acidic protein () | BDBM474341 (6-(bis(3-fluorophenyl)methyl)-11-hydroxy- 5,6-dihy...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/... | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polymerase acidic protein () | BDBM474348 ((S)-6-benzhydryl-11-hydroxy-2,3-dimethyl- 5H-imida...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/... | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polymerase acidic protein () | BDBM474363 ((S)-6-benzhydryl-11-hydroxy-3- (methoxymethyl)-5,6...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/... | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polymerase acidic protein () | BDBM474369 ((S)-6-benzhydryl-11-hydroxy-3- (hydroxymethyl)-5,6...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/... | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polymerase acidic protein () | BDBM474365 (6-benzhydryl-11-hydroxy-5,5-dimethyl-5,6- dihydro-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/... | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polymerase acidic protein () | BDBM474352 ((S)-6-((R)-(4-fluorophenyl)(6- (trifluoromethyl)py...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/... | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polymerase acidic protein () | BDBM474342 (6-benzhydryl-11-hydroxy-5,6-dihydro-10H- [1,2,4]tr...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/... | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuraminidase (Influenza A virus (strain A/Wilson-Smith/1933 H1N1...) | BDBM474368 ((S)-6-(bis(4-fluorophenyl)methyl)-3-bromo- 11-hydr...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 290 | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description For influenza NA assays, MDCK cells were plated in Phenol Red-free DMEM (Gibco) supplemented with 2 mM L-Glutamine, 1% sodium pyruvate (Cellgro, Mana... | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuraminidase () | BDBM474372 ((S)-6-benzhydryl-11-hydroxy-3- ((methylamino)methy...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 3.40E+3 | n/a | n/a | n/a | n/a |
Novartis AG US Patent | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuraminidase (Influenza A virus (strain A/Wilson-Smith/1933 H1N1...) | BDBM474373 ((S)-6-benzhydryl-3- ((cyclohexylamino)methyl)-11-h...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 3.20E+3 | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description For influenza NA assays, MDCK cells were plated in Phenol Red-free DMEM (Gibco) supplemented with 2 mM L-Glutamine, 1% sodium pyruvate (Cellgro, Mana... | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuraminidase (Influenza A virus (strain A/Wilson-Smith/1933 H1N1...) | BDBM474378 ((S)-6-benzhydryl-11-hydroxy-N-(2- methoxyethyl)-10...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 1.90E+4 | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description For influenza NA assays, MDCK cells were plated in Phenol Red-free DMEM (Gibco) supplemented with 2 mM L-Glutamine, 1% sodium pyruvate (Cellgro, Mana... | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuraminidase () | BDBM474378 ((S)-6-benzhydryl-11-hydroxy-N-(2- methoxyethyl)-10...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 2.70E+4 | n/a | n/a | n/a | n/a |
Novartis AG US Patent | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuraminidase (Influenza A virus (strain A/Memphis/1/1971 H3N2)) | BDBM474379 (6-benzhydryl-11-hydroxy-6H,10H- spiro[imidazo[1,2-...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a |
Novartis AG US Patent | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuraminidase (Influenza A virus (strain A/Wilson-Smith/1933 H1N1...) | BDBM474367 ((S)-6-((S)-(3-bromophenyl)(4- fluorophenyl)methyl)...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 45 | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description For influenza NA assays, MDCK cells were plated in Phenol Red-free DMEM (Gibco) supplemented with 2 mM L-Glutamine, 1% sodium pyruvate (Cellgro, Mana... | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuraminidase (Influenza A virus (strain A/Memphis/1/1971 H3N2)) | BDBM474375 ((S)-6-benzhydryl-11-hydroxy-3- (morpholinomethyl)-...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a |
Novartis AG US Patent | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuraminidase () | BDBM474376 ((S)-6-benzhydryl-11-hydroxy-N,N-dimethyl- 10-oxo-5...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 1.70E+4 | n/a | n/a | n/a | n/a |
Novartis AG US Patent | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuraminidase () | BDBM474367 ((S)-6-((S)-(3-bromophenyl)(4- fluorophenyl)methyl)...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 65 | n/a | n/a | n/a | n/a |
Novartis AG US Patent | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuraminidase () | BDBM474370 ((S)-6-benzhydryl-11-hydroxy-3- (trifluoromethyl)-5...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 820 | n/a | n/a | n/a | n/a |
Novartis AG US Patent | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuraminidase (Influenza A virus (strain A/Memphis/1/1971 H3N2)) | BDBM474378 ((S)-6-benzhydryl-11-hydroxy-N-(2- methoxyethyl)-10...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a |
Novartis AG US Patent | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuraminidase () | BDBM474379 (6-benzhydryl-11-hydroxy-6H,10H- spiro[imidazo[1,2-...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 390 | n/a | n/a | n/a | n/a |
Novartis AG US Patent | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuraminidase (Influenza A virus (strain A/Memphis/1/1971 H3N2)) | BDBM474380 (5-benzhydryl-10-hydroxy-3-methyl-4,5- dihydroimida...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a |
Novartis AG US Patent | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuraminidase (Influenza A virus (strain A/Memphis/1/1971 H3N2)) | BDBM474368 ((S)-6-(bis(4-fluorophenyl)methyl)-3-bromo- 11-hydr...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 840 | n/a | n/a | n/a | n/a |
Novartis AG US Patent | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuraminidase (Influenza A virus (strain A/Memphis/1/1971 H3N2)) | BDBM474369 ((S)-6-benzhydryl-11-hydroxy-3- (hydroxymethyl)-5,6...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 4.60E+3 | n/a | n/a | n/a | n/a |
Novartis AG US Patent | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuraminidase (Influenza A virus (strain A/Memphis/1/1971 H3N2)) | BDBM474377 ((S)-6-benzhydryl-11-hydroxy-N-methyl-10- oxo-5,6-d...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a |
Novartis AG US Patent | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuraminidase () | BDBM474377 ((S)-6-benzhydryl-11-hydroxy-N-methyl-10- oxo-5,6-d...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 1.40E+4 | n/a | n/a | n/a | n/a |
Novartis AG US Patent | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuraminidase () | BDBM474368 ((S)-6-(bis(4-fluorophenyl)methyl)-3-bromo- 11-hydr...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 560 | n/a | n/a | n/a | n/a |
Novartis AG US Patent | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuraminidase (Influenza A virus (strain A/Wilson-Smith/1933 H1N1...) | BDBM474375 ((S)-6-benzhydryl-11-hydroxy-3- (morpholinomethyl)-...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 4.10E+3 | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description For influenza NA assays, MDCK cells were plated in Phenol Red-free DMEM (Gibco) supplemented with 2 mM L-Glutamine, 1% sodium pyruvate (Cellgro, Mana... | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuraminidase () | BDBM474375 ((S)-6-benzhydryl-11-hydroxy-3- (morpholinomethyl)-...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 3.80E+3 | n/a | n/a | n/a | n/a |
Novartis AG US Patent | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuraminidase (Influenza A virus (strain A/Wilson-Smith/1933 H1N1...) | BDBM474370 ((S)-6-benzhydryl-11-hydroxy-3- (trifluoromethyl)-5...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 200 | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description For influenza NA assays, MDCK cells were plated in Phenol Red-free DMEM (Gibco) supplemented with 2 mM L-Glutamine, 1% sodium pyruvate (Cellgro, Mana... | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuraminidase (Influenza A virus (strain A/Memphis/1/1971 H3N2)) | BDBM474371 ((S)-6-benzhydryl-11-hydroxy-10-oxo-5,6- dihydro-10...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 5.70E+3 | n/a | n/a | n/a | n/a |
Novartis AG US Patent | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuraminidase (Influenza A virus (strain A/Memphis/1/1971 H3N2)) | BDBM474372 ((S)-6-benzhydryl-11-hydroxy-3- ((methylamino)methy...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 5.70E+3 | n/a | n/a | n/a | n/a |
Novartis AG US Patent | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuraminidase () | BDBM474373 ((S)-6-benzhydryl-3- ((cyclohexylamino)methyl)-11-h...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 3.90E+3 | n/a | n/a | n/a | n/a |
Novartis AG US Patent | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuraminidase () | BDBM474374 ((S)-6-benzhydryl-3-((dimethylamino)methyl)- 11-hyd...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 2.40E+3 | n/a | n/a | n/a | n/a |
Novartis AG US Patent | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuraminidase (Influenza A virus (strain A/Wilson-Smith/1933 H1N1...) | BDBM474376 ((S)-6-benzhydryl-11-hydroxy-N,N-dimethyl- 10-oxo-5...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 6.30E+3 | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description For influenza NA assays, MDCK cells were plated in Phenol Red-free DMEM (Gibco) supplemented with 2 mM L-Glutamine, 1% sodium pyruvate (Cellgro, Mana... | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuraminidase (Influenza A virus (strain A/Memphis/1/1971 H3N2)) | BDBM474376 ((S)-6-benzhydryl-11-hydroxy-N,N-dimethyl- 10-oxo-5...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 3.20E+4 | n/a | n/a | n/a | n/a |
Novartis AG US Patent | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuraminidase () | BDBM474380 (5-benzhydryl-10-hydroxy-3-methyl-4,5- dihydroimida...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a |
Novartis AG US Patent | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuraminidase (Influenza A virus (strain A/Memphis/1/1971 H3N2)) | BDBM474367 ((S)-6-((S)-(3-bromophenyl)(4- fluorophenyl)methyl)...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 190 | n/a | n/a | n/a | n/a |
Novartis AG US Patent | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuraminidase (Influenza A virus (strain A/Wilson-Smith/1933 H1N1...) | BDBM474369 ((S)-6-benzhydryl-11-hydroxy-3- (hydroxymethyl)-5,6...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description For influenza NA assays, MDCK cells were plated in Phenol Red-free DMEM (Gibco) supplemented with 2 mM L-Glutamine, 1% sodium pyruvate (Cellgro, Mana... | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuraminidase () | BDBM474369 ((S)-6-benzhydryl-11-hydroxy-3- (hydroxymethyl)-5,6...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a |
Novartis AG US Patent | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuraminidase (Influenza A virus (strain A/Wilson-Smith/1933 H1N1...) | BDBM474371 ((S)-6-benzhydryl-11-hydroxy-10-oxo-5,6- dihydro-10...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description For influenza NA assays, MDCK cells were plated in Phenol Red-free DMEM (Gibco) supplemented with 2 mM L-Glutamine, 1% sodium pyruvate (Cellgro, Mana... | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuraminidase () | BDBM474371 ((S)-6-benzhydryl-11-hydroxy-10-oxo-5,6- dihydro-10...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a |
Novartis AG US Patent | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuraminidase (Influenza A virus (strain A/Memphis/1/1971 H3N2)) | BDBM474373 ((S)-6-benzhydryl-3- ((cyclohexylamino)methyl)-11-h...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 6.10E+3 | n/a | n/a | n/a | n/a |
Novartis AG US Patent | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuraminidase (Influenza A virus (strain A/Wilson-Smith/1933 H1N1...) | BDBM474374 ((S)-6-benzhydryl-3-((dimethylamino)methyl)- 11-hyd...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description For influenza NA assays, MDCK cells were plated in Phenol Red-free DMEM (Gibco) supplemented with 2 mM L-Glutamine, 1% sodium pyruvate (Cellgro, Mana... | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuraminidase (Influenza A virus (strain A/Memphis/1/1971 H3N2)) | BDBM474374 ((S)-6-benzhydryl-3-((dimethylamino)methyl)- 11-hyd...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 4.30E+3 | n/a | n/a | n/a | n/a |
Novartis AG US Patent | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuraminidase (Influenza A virus (strain A/Wilson-Smith/1933 H1N1...) | BDBM474377 ((S)-6-benzhydryl-11-hydroxy-N-methyl-10- oxo-5,6-d...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description For influenza NA assays, MDCK cells were plated in Phenol Red-free DMEM (Gibco) supplemented with 2 mM L-Glutamine, 1% sodium pyruvate (Cellgro, Mana... | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuraminidase (Influenza A virus (strain A/Wilson-Smith/1933 H1N1...) | BDBM474379 (6-benzhydryl-11-hydroxy-6H,10H- spiro[imidazo[1,2-...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 610 | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description For influenza NA assays, MDCK cells were plated in Phenol Red-free DMEM (Gibco) supplemented with 2 mM L-Glutamine, 1% sodium pyruvate (Cellgro, Mana... | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuraminidase (Influenza A virus (strain A/Memphis/1/1971 H3N2)) | BDBM474370 ((S)-6-benzhydryl-11-hydroxy-3- (trifluoromethyl)-5...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a |
Novartis AG US Patent | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuraminidase (Influenza A virus (strain A/Wilson-Smith/1933 H1N1...) | BDBM474372 ((S)-6-benzhydryl-11-hydroxy-3- ((methylamino)methy...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description For influenza NA assays, MDCK cells were plated in Phenol Red-free DMEM (Gibco) supplemented with 2 mM L-Glutamine, 1% sodium pyruvate (Cellgro, Mana... | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuraminidase (Influenza A virus (strain A/Wilson-Smith/1933 H1N1...) | BDBM474380 (5-benzhydryl-10-hydroxy-3-methyl-4,5- dihydroimida...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description For influenza NA assays, MDCK cells were plated in Phenol Red-free DMEM (Gibco) supplemented with 2 mM L-Glutamine, 1% sodium pyruvate (Cellgro, Mana... | US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ | |||||||||||
More data for this Ligand-Target Pair |