BDBM474353 (S)-6-(bis(3-fluorophenyl)methyl)-11- hydroxy-5,6-dihydro-10H- imidazo[2',1':3,4]pyrazino[1,2-b]pyridazin-10- one::US10858366, Example 23
SMILES: Oc1c2-c3nccn3C[C@H](C(c3cccc(F)c3)c3cccc(F)c3)n2ncc1=O
InChI Key: InChIKey=LQVPPYWQWNAIED-QGZVFWFLSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Polymerase acidic protein () | BDBM474353 ((S)-6-(bis(3-fluorophenyl)methyl)-11- hydroxy-5,6-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/... | US Patent US10858366 (2020) | |||||||||||
More data for this Ligand-Target Pair |