Affinity Data by Patent

Patent code US9266828

Found 5 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Furin (Homo sapiens (Human))	BDBM207839 (US9266828, B) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.70	n/a	n/a	n/a	n/a	7.5	310.15
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE US Patent					Assay Description Furin activity was measured in triplicate in wells of a 96-well plate in 0.2 ml 50 mM HEPES, pH 7.5, containing 1 mM CaCl2, 0.005% Brij-35 and 20% gl...				US Patent US9266828 (2016) BindingDB Entry DOI: 10.7270/Q26T0KFM
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE US Patent					More data for this Ligand-Target Pair
Furin (Homo sapiens (Human))	BDBM207838 (US9266828, A) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	7.5	310.15
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE US Patent					Assay Description Furin activity was measured in triplicate in wells of a 96-well plate in 0.2 ml 50 mM HEPES, pH 7.5, containing 1 mM CaCl2, 0.005% Brij-35 and 20% gl...				US Patent US9266828 (2016) BindingDB Entry DOI: 10.7270/Q26T0KFM
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE US Patent					More data for this Ligand-Target Pair
Furin (Homo sapiens (Human))	BDBM207840 (US9266828, C) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	7.5	310.15
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE US Patent					Assay Description Furin activity was measured in triplicate in wells of a 96-well plate in 0.2 ml 50 mM HEPES, pH 7.5, containing 1 mM CaCl2, 0.005% Brij-35 and 20% gl...				US Patent US9266828 (2016) BindingDB Entry DOI: 10.7270/Q26T0KFM
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE US Patent					More data for this Ligand-Target Pair
Furin (Homo sapiens (Human))	BDBM207842 (US9266828, E) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	300	n/a	n/a	n/a	n/a	7.5	310.15
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE US Patent					Assay Description Furin activity was measured in triplicate in wells of a 96-well plate in 0.2 ml 50 mM HEPES, pH 7.5, containing 1 mM CaCl2, 0.005% Brij-35 and 20% gl...				US Patent US9266828 (2016) BindingDB Entry DOI: 10.7270/Q26T0KFM
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE US Patent					More data for this Ligand-Target Pair
Furin (Homo sapiens (Human))	BDBM207841 (US9266828, D) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	7.5	310.15
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE US Patent					Assay Description Furin activity was measured in triplicate in wells of a 96-well plate in 0.2 ml 50 mM HEPES, pH 7.5, containing 1 mM CaCl2, 0.005% Brij-35 and 20% gl...				US Patent US9266828 (2016) BindingDB Entry DOI: 10.7270/Q26T0KFM
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE US Patent					More data for this Ligand-Target Pair

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Change energy units to:kcal/mole

* indicates data uncertainty>20%