Affinity Data by Patent

Patent code US8552057

Found 12 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Estrogen receptor beta (Homo sapiens (Human))	BDBM23451 (5,14-dihydroxy-8,17-dioxatetracyclo[8.7.0.0^{2,7}....) Show SMILES Oc1ccc2c(c1)oc1c2c(=O)oc2cc(O)ccc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	US Patent	n/a	n/a	18.6	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern California US Patent					Assay Description The binding affinity and selectivity of candidate molecules yielded from database screening were determined by a fluorescent polarization competiti...				US Patent US8552057 (2013) BindingDB Entry DOI: 10.7270/Q2CZ35TN
University of Southern California US Patent					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM23451 (5,14-dihydroxy-8,17-dioxatetracyclo[8.7.0.0^{2,7}....) Show SMILES Oc1ccc2c(c1)oc1c2c(=O)oc2cc(O)ccc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB US Patent	n/a	n/a	75.7	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern California US Patent					Assay Description The binding affinity and selectivity of candidate molecules yielded from database screening were determined by a fluorescent polarization competiti...				US Patent US8552057 (2013) BindingDB Entry DOI: 10.7270/Q2CZ35TN
University of Southern California US Patent					More data for this Ligand-Target Pair				3D Structure (crystal)
Estrogen receptor beta (Homo sapiens (Human))	BDBM19459 (5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one...) Show SMILES Oc1ccc(cc1)-c1coc2cc(O)cc(O)c2c1=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB US Patent	n/a	n/a	98.7	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern California US Patent					Assay Description The binding affinity and selectivity of candidate molecules yielded from database screening were determined by a fluorescent polarization competiti...				US Patent US8552057 (2013) BindingDB Entry DOI: 10.7270/Q2CZ35TN
University of Southern California US Patent					More data for this Ligand-Target Pair				3D Structure (crystal)
Estrogen receptor (Homo sapiens (Human))	BDBM103430 (US8552057, 5) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern California US Patent					Assay Description The binding affinity and selectivity of candidate molecules yielded from database screening were determined by a fluorescent polarization competiti...				US Patent US8552057 (2013) BindingDB Entry DOI: 10.7270/Q2CZ35TN
University of Southern California US Patent					More data for this Ligand-Target Pair
Estrogen receptor beta (Homo sapiens (Human))	BDBM103430 (US8552057, 5) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern California US Patent					Assay Description The binding affinity and selectivity of candidate molecules yielded from database screening were determined by a fluorescent polarization competiti...				US Patent US8552057 (2013) BindingDB Entry DOI: 10.7270/Q2CZ35TN
University of Southern California US Patent					More data for this Ligand-Target Pair
Estrogen receptor beta (Homo sapiens (Human))	BDBM50166895 (3-(4-Hydroxy-phenyl)-4H-chromen-7-ol \| CHEMBL19556...) Show SMILES Oc1ccc(cc1)C1=COc2cc(O)ccc2C1 \|t:8\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	US Patent	n/a	n/a	680	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern California US Patent					Assay Description The binding affinity and selectivity of candidate molecules yielded from database screening were determined by a fluorescent polarization competiti...				US Patent US8552057 (2013) BindingDB Entry DOI: 10.7270/Q2CZ35TN
University of Southern California US Patent					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50166897 (CHEMBL192548 \| Furan-2-carboxylic acid 2-oxo-4-phe...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	2.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern California US Patent					Assay Description The binding affinity and selectivity of candidate molecules yielded from database screening were determined by a fluorescent polarization competiti...				US Patent US8552057 (2013) BindingDB Entry DOI: 10.7270/Q2CZ35TN
University of Southern California US Patent					More data for this Ligand-Target Pair
Estrogen receptor beta (Homo sapiens (Human))	BDBM23420 (7,4′-Dihydroxy-isoflavone (3a) \| 7-hydroxy-3...) Show SMILES Oc1ccc(cc1)-c1coc2cc(O)ccc2c1=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	US Patent	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern California US Patent					Assay Description The binding affinity and selectivity of candidate molecules yielded from database screening were determined by a fluorescent polarization competiti...				US Patent US8552057 (2013) BindingDB Entry DOI: 10.7270/Q2CZ35TN
University of Southern California US Patent					More data for this Ligand-Target Pair
Estrogen receptor beta (Homo sapiens (Human))	BDBM50166894 (6-Hydroxy-2-(4-hydroxy-3-methoxy-phenyl)-chromen-4...) Show SMILES COc1cc(ccc1O)-c1cc(=O)c2cc(O)ccc2o1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	4.48E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern California US Patent					Assay Description The binding affinity and selectivity of candidate molecules yielded from database screening were determined by a fluorescent polarization competiti...				US Patent US8552057 (2013) BindingDB Entry DOI: 10.7270/Q2CZ35TN
University of Southern California US Patent					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM19459 (5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one...) Show SMILES Oc1ccc(cc1)-c1coc2cc(O)cc(O)c2c1=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB US Patent	n/a	n/a	4.68E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern California US Patent					Assay Description The binding affinity and selectivity of candidate molecules yielded from database screening were determined by a fluorescent polarization competiti...				US Patent US8552057 (2013) BindingDB Entry DOI: 10.7270/Q2CZ35TN
University of Southern California US Patent					More data for this Ligand-Target Pair				3D Structure (crystal)
Estrogen receptor beta (Homo sapiens (Human))	BDBM50166898 (2-Benzofuran-2-yl-1-(2,4-dihydroxy-phenyl)-ethanon...) Show SMILES Oc1ccc(C(=O)Cc2cc3ccccc3o2)c(O)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	US Patent	n/a	n/a	4.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern California US Patent					Assay Description The binding affinity and selectivity of candidate molecules yielded from database screening were determined by a fluorescent polarization competiti...				US Patent US8552057 (2013) BindingDB Entry DOI: 10.7270/Q2CZ35TN
University of Southern California US Patent					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50166898 (2-Benzofuran-2-yl-1-(2,4-dihydroxy-phenyl)-ethanon...) Show SMILES Oc1ccc(C(=O)Cc2cc3ccccc3o2)c(O)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	US Patent	n/a	n/a	8.57E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern California US Patent					Assay Description The binding affinity and selectivity of candidate molecules yielded from database screening were determined by a fluorescent polarization competiti...				US Patent US8552057 (2013) BindingDB Entry DOI: 10.7270/Q2CZ35TN
University of Southern California US Patent					More data for this Ligand-Target Pair

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* indicates data uncertainty>20%