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Patent code US8618286

Compile Data Set for Download or QSAR
Found 87 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Nitric oxide synthase, brain


(Homo sapiens (Human))		BDBM111496
PNG
(US8618286, 22)
Show SMILES CN(C)CCCN1CCSc2cc(ccc12)N=C(N)c1cccs1 |w:16.17|
Show InChI InChI=1S/C18H24N4S2/c1-21(2)8-4-9-22-10-12-24-17-13-14(6-7-15(17)22)20-18(19)16-5-3-11-23-16/h3,5-7,11,13H,4,8-10,12H2,1-2H3,(H2,19,20)
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US Patent
n/an/a 14n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, brain


(Homo sapiens (Human))		BDBM111497
PNG
(US8618286, 23)
Show SMILES CNCCCN1CCSc2cc(ccc12)N=C(N)c1cccs1 |w:15.16|
Show InChI InChI=1S/C17H22N4S2/c1-19-7-3-8-21-9-11-23-16-12-13(5-6-14(16)21)20-17(18)15-4-2-10-22-15/h2,4-6,10,12,19H,3,7-9,11H2,1H3,(H2,18,20)
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n/an/a 28n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, brain


(Homo sapiens (Human))		BDBM111490
PNG
(US8618286, 16)
Show SMILES NC(=Nc1ccc2N(CCNCCO)CCSc2c1)c1cccs1 |w:2.2|
Show InChI InChI=1S/C17H22N4OS2/c18-17(15-2-1-10-23-15)20-13-3-4-14-16(12-13)24-11-8-21(14)7-5-19-6-9-22/h1-4,10,12,19,22H,5-9,11H2,(H2,18,20)
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n/an/a 34n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, brain


(Homo sapiens (Human))		BDBM111498
PNG
(US8618286, 24)
Show SMILES CCNCCN1CCSc2ccc(cc12)N=C(N)c1cccs1 |w:15.16|
Show InChI InChI=1S/C17H22N4S2/c1-2-19-7-8-21-9-11-23-15-6-5-13(12-14(15)21)20-17(18)16-4-3-10-22-16/h3-6,10,12,19H,2,7-9,11H2,1H3,(H2,18,20)
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n/an/a 50n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, brain


(Homo sapiens (Human))		BDBM111482
PNG
(US8618286, 8)
Show SMILES CNCCN1CCSc2cc(ccc12)N=C(N)c1cccs1 |w:14.15|
Show InChI InChI=1S/C16H20N4S2/c1-18-6-7-20-8-10-22-15-11-12(4-5-13(15)20)19-16(17)14-3-2-9-21-14/h2-5,9,11,18H,6-8,10H2,1H3,(H2,17,19)
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n/an/a 60n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, brain


(Homo sapiens (Human))		BDBM111484
PNG
(US8618286, 10)
Show SMILES CNCCN1CCOc2ccc(cc12)N=C(N)c1cccs1 |w:14.15|
Show InChI InChI=1S/C16H20N4OS/c1-18-6-7-20-8-9-21-14-5-4-12(11-13(14)20)19-16(17)15-3-2-10-22-15/h2-5,10-11,18H,6-9H2,1H3,(H2,17,19)
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n/an/a 80n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, brain


(Homo sapiens (Human))		BDBM111502
PNG
(US8618286, 28)
Show SMILES CNCCN1CCSc2ccc(cc12)N=C(N)c1cccs1 |w:14.15|
Show InChI InChI=1S/C16H20N4S2/c1-18-6-7-20-8-10-22-14-5-4-12(11-13(14)20)19-16(17)15-3-2-9-21-15/h2-5,9,11,18H,6-8,10H2,1H3,(H2,17,19)
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n/an/a 80n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, brain


(Homo sapiens (Human))		BDBM111503
PNG
(US8618286, 29)
Show SMILES NC(=Nc1ccc2SCCN(C3CCNCC3)c2c1)c1cccs1 |w:2.2|
Show InChI InChI=1S/C18H22N4S2/c19-18(17-2-1-10-23-17)21-13-3-4-16-15(12-13)22(9-11-24-16)14-5-7-20-8-6-14/h1-4,10,12,14,20H,5-9,11H2,(H2,19,21)
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n/an/a 110n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, brain


(Homo sapiens (Human))		BDBM111486
PNG
(US8618286, 12)
Show SMILES CN(C)CCN1CCSc2cc(ccc12)N=C(N)c1cccs1 |w:15.16|
Show InChI InChI=1S/C17H22N4S2/c1-20(2)7-8-21-9-11-23-16-12-13(5-6-14(16)21)19-17(18)15-4-3-10-22-15/h3-6,10,12H,7-9,11H2,1-2H3,(H2,18,19)
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n/an/a 120n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, brain


(Homo sapiens (Human))		BDBM111501
PNG
(US8618286, 27)
Show SMILES CN(C)CCN1CCSc2ccc(cc12)N=C(N)c1cccs1 |w:15.16|
Show InChI InChI=1S/C17H22N4S2/c1-20(2)7-8-21-9-11-23-15-6-5-13(12-14(15)21)19-17(18)16-4-3-10-22-16/h3-6,10,12H,7-9,11H2,1-2H3,(H2,18,19)
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n/an/a 130n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, brain


(Homo sapiens (Human))		BDBM111495
PNG
(US8618286, 21)
Show SMILES NC(=Nc1ccc2N(CCCN3CCCC3)CCSc2c1)c1cccs1 |w:2.2|
Show InChI InChI=1S/C20H26N4S2/c21-20(18-5-3-13-25-18)22-16-6-7-17-19(15-16)26-14-12-24(17)11-4-10-23-8-1-2-9-23/h3,5-7,13,15H,1-2,4,8-12,14H2,(H2,21,22)
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n/an/a 140n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, brain


(Homo sapiens (Human))		BDBM111488
PNG
(US8618286, 14)
Show SMILES NC(=Nc1ccc2N(CCN3CCCCC3)CCSc2c1)c1cccs1 |w:2.2|
Show InChI InChI=1S/C20H26N4S2/c21-20(18-5-4-13-25-18)22-16-6-7-17-19(15-16)26-14-12-24(17)11-10-23-8-2-1-3-9-23/h4-7,13,15H,1-3,8-12,14H2,(H2,21,22)
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n/an/a 140n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, brain


(Homo sapiens (Human))		BDBM111493
PNG
(US8618286, 19)
Show SMILES CN(C)CCN1CCSc2cc(ccc12)N=C(N)c1ccco1 |w:15.16|
Show InChI InChI=1S/C17H22N4OS/c1-20(2)7-8-21-9-11-23-16-12-13(5-6-14(16)21)19-17(18)15-4-3-10-22-15/h3-6,10,12H,7-9,11H2,1-2H3,(H2,18,19)
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n/an/a 140n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, brain


(Homo sapiens (Human))		BDBM111500
PNG
(US8618286, 26)
Show SMILES NC(=Nc1ccc2SCCN(CCNCCO)c2c1)c1cccs1 |w:2.2|
Show InChI InChI=1S/C17H22N4OS2/c18-17(16-2-1-10-23-16)20-13-3-4-15-14(12-13)21(8-11-24-15)7-5-19-6-9-22/h1-4,10,12,19,22H,5-9,11H2,(H2,18,20)
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n/an/a 150n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, brain


(Homo sapiens (Human))		BDBM111489
PNG
(US8618286, 15)
Show SMILES CCN(CC)CCN1CCSc2cc(ccc12)N=C(N)c1cccs1 |w:17.18|
Show InChI InChI=1S/C19H26N4S2/c1-3-22(4-2)9-10-23-11-13-25-18-14-15(7-8-16(18)23)21-19(20)17-6-5-12-24-17/h5-8,12,14H,3-4,9-11,13H2,1-2H3,(H2,20,21)
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n/an/a 150n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, brain


(Homo sapiens (Human))		BDBM111494
PNG
(US8618286, 20)
Show SMILES CNCCN1CCSc2cc(ccc12)N=C(N)c1ccco1 |w:14.15|
Show InChI InChI=1S/C16H20N4OS/c1-18-6-7-20-8-10-22-15-11-12(4-5-13(15)20)19-16(17)14-3-2-9-21-14/h2-5,9,11,18H,6-8,10H2,1H3,(H2,17,19)
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n/an/a 160n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, brain


(Homo sapiens (Human))		BDBM111487
PNG
(US8618286, 13)
Show SMILES CN1CCCC1CCN1CCSc2cc(ccc12)N=C(N)c1cccs1 |w:18.20|
Show InChI InChI=1S/C20H26N4S2/c1-23-9-2-4-16(23)8-10-24-11-13-26-19-14-15(6-7-17(19)24)22-20(21)18-5-3-12-25-18/h3,5-7,12,14,16H,2,4,8-11,13H2,1H3,(H2,21,22)
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n/an/a 190n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, brain


(Homo sapiens (Human))		BDBM111499
PNG
(US8618286, 25)
Show SMILES NC(=Nc1ccc2SCCN(CCN3CCCC3)c2c1)c1cccs1 |w:2.2|
Show InChI InChI=1S/C19H24N4S2/c20-19(18-4-3-12-24-18)21-15-5-6-17-16(14-15)23(11-13-25-17)10-9-22-7-1-2-8-22/h3-6,12,14H,1-2,7-11,13H2,(H2,20,21)
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n/an/a 200n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, brain


(Homo sapiens (Human))		BDBM111483
PNG
(US8618286, 9)
Show SMILES CN(C)CCN1CCOc2ccc(cc12)N=C(N)c1cccs1 |w:15.16|
Show InChI InChI=1S/C17H22N4OS/c1-20(2)7-8-21-9-10-22-15-6-5-13(12-14(15)21)19-17(18)16-4-3-11-23-16/h3-6,11-12H,7-10H2,1-2H3,(H2,18,19)
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n/an/a 200n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, brain


(Homo sapiens (Human))		BDBM111480
PNG
(US8618286, 6)
Show SMILES CN(C)CCN1CCOc2cc(ccc12)N=C(N)c1cccs1 |w:15.16|
Show InChI InChI=1S/C17H22N4OS/c1-20(2)7-8-21-9-10-22-15-12-13(5-6-14(15)21)19-17(18)16-4-3-11-23-16/h3-6,11-12H,7-10H2,1-2H3,(H2,18,19)
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n/an/a 200n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, brain


(Homo sapiens (Human))		BDBM111485
PNG
(US8618286, 11)
Show SMILES NC(=Nc1ccc2N(CCN3CCCC3)CCSc2c1)c1cccs1 |w:2.2|
Show InChI InChI=1S/C19H24N4S2/c20-19(17-4-3-12-24-17)21-15-5-6-16-18(14-15)25-13-11-23(16)10-9-22-7-1-2-8-22/h3-6,12,14H,1-2,7-11,13H2,(H2,20,21)
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US Patent
n/an/a 240n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, brain


(Homo sapiens (Human))		BDBM111478
PNG
(US8618286, 4)
Show SMILES NC(=Nc1ccc2N(CCN3CCCC3)CCOc2c1)c1cccs1 |w:2.2|
Show InChI InChI=1S/C19H24N4OS/c20-19(18-4-3-13-25-18)21-15-5-6-16-17(14-15)24-12-11-23(16)10-9-22-7-1-2-8-22/h3-6,13-14H,1-2,7-12H2,(H2,20,21)
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n/an/a 410n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, brain


(Homo sapiens (Human))		BDBM111476
PNG
(US8618286, 2)
Show SMILES CN1CCCC1CCN1CCOc2cc(ccc12)N=C(N)c1cccs1 |w:18.20|
Show InChI InChI=1S/C20H26N4OS/c1-23-9-2-4-16(23)8-10-24-11-12-25-18-14-15(6-7-17(18)24)22-20(21)19-5-3-13-26-19/h3,5-7,13-14,16H,2,4,8-12H2,1H3,(H2,21,22)
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n/an/a 430n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, brain


(Homo sapiens (Human))		BDBM111492
PNG
(US8618286, 18)
Show SMILES NC(=Nc1ccc2N(CCN3CCC[C@H]3C(O)=O)CCSc2c1)c1cccs1 |r,w:2.2|
Show InChI InChI=1S/C20H24N4O2S2/c21-19(17-4-2-11-27-17)22-14-5-6-15-18(13-14)28-12-10-24(15)9-8-23-7-1-3-16(23)20(25)26/h2,4-6,11,13,16H,1,3,7-10,12H2,(H2,21,22)(H,25,26)/t16-/m0/s1
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n/an/a 660n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, brain


(Homo sapiens (Human))		BDBM111477
PNG
(US8618286, 3)
Show SMILES NC(=Nc1ccc2N(CCN3CCCC3)C(=O)COc2c1)c1cccs1 |w:2.2|
Show InChI InChI=1S/C19H22N4O2S/c20-19(17-4-3-11-26-17)21-14-5-6-15-16(12-14)25-13-18(24)23(15)10-9-22-7-1-2-8-22/h3-6,11-12H,1-2,7-10,13H2,(H2,20,21)
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n/an/a 850n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, brain


(Homo sapiens (Human))		BDBM111481
PNG
(US8618286, 7)
Show SMILES CCNCCN1CCOc2cc(ccc12)N=C(N)c1cccs1 |w:15.16|
Show InChI InChI=1S/C17H22N4OS/c1-2-19-7-8-21-9-10-22-15-12-13(5-6-14(15)21)20-17(18)16-4-3-11-23-16/h3-6,11-12,19H,2,7-10H2,1H3,(H2,18,20)
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n/an/a 1.06E+3n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, brain


(Homo sapiens (Human))		BDBM111491
PNG
(US8618286, 17)
Show SMILES CN(CCN1CCSc2cc(ccc12)N=C(N)c1cccs1)CC(O)=O |w:14.15|
Show InChI InChI=1S/C18H22N4O2S2/c1-21(12-17(23)24)6-7-22-8-10-26-16-11-13(4-5-14(16)22)20-18(19)15-3-2-9-25-15/h2-5,9,11H,6-8,10,12H2,1H3,(H2,19,20)(H,23,24)
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n/an/a 1.16E+3n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, inducible


(Homo sapiens (Human))		BDBM111477
PNG
(US8618286, 3)
Show SMILES NC(=Nc1ccc2N(CCN3CCCC3)C(=O)COc2c1)c1cccs1 |w:2.2|
Show InChI InChI=1S/C19H22N4O2S/c20-19(17-4-3-11-26-17)21-14-5-6-15-16(12-14)25-13-18(24)23(15)10-9-22-7-1-2-8-22/h3-6,11-12H,1-2,7-10,13H2,(H2,20,21)
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n/an/a 1.50E+3n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Recombinant human inducible NOS (iNOS) was produced in Baculovirus-infected Sf9 cells (ALEXIS). In a radiometric method, NO synthase activity was det...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, brain


(Homo sapiens (Human))		BDBM111479
PNG
(US8618286, 5)
Show SMILES CN(C)CCN1C(=O)COc2cc(ccc12)N=C(N)c1cccs1 |w:16.17|
Show InChI InChI=1S/C17H20N4O2S/c1-20(2)7-8-21-13-6-5-12(10-14(13)23-11-16(21)22)19-17(18)15-4-3-9-24-15/h3-6,9-10H,7-8,11H2,1-2H3,(H2,18,19)
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n/an/a 1.84E+3n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, brain


(Homo sapiens (Human))		BDBM111475
PNG
(US8618286, 1)
Show SMILES CN1CCCC1CCN1C(=O)COc2cc(ccc12)N=C(N)c1cccs1 |w:19.21|
Show InChI InChI=1S/C20H24N4O2S/c1-23-9-2-4-15(23)8-10-24-16-7-6-14(12-17(16)26-13-19(24)25)22-20(21)18-5-3-11-27-18/h3,5-7,11-12,15H,2,4,8-10,13H2,1H3,(H2,21,22)
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n/an/a 2.08E+3n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, inducible


(Homo sapiens (Human))		BDBM111478
PNG
(US8618286, 4)
Show SMILES NC(=Nc1ccc2N(CCN3CCCC3)CCOc2c1)c1cccs1 |w:2.2|
Show InChI InChI=1S/C19H24N4OS/c20-19(18-4-3-13-25-18)21-15-5-6-16-17(14-15)24-12-11-23(16)10-9-22-7-1-2-8-22/h3-6,13-14H,1-2,7-12H2,(H2,20,21)
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n/an/a 2.70E+3n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Recombinant human inducible NOS (iNOS) was produced in Baculovirus-infected Sf9 cells (ALEXIS). In a radiometric method, NO synthase activity was det...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, inducible


(Homo sapiens (Human))		BDBM111484
PNG
(US8618286, 10)
Show SMILES CNCCN1CCOc2ccc(cc12)N=C(N)c1cccs1 |w:14.15|
Show InChI InChI=1S/C16H20N4OS/c1-18-6-7-20-8-9-21-14-5-4-12(11-13(14)20)19-16(17)15-3-2-10-22-15/h2-5,10-11,18H,6-9H2,1H3,(H2,17,19)
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n/an/a 3.74E+3n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Recombinant human inducible NOS (iNOS) was produced in Baculovirus-infected Sf9 cells (ALEXIS). In a radiometric method, NO synthase activity was det...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, endothelial


(Homo sapiens (Human))		BDBM111484
PNG
(US8618286, 10)
Show SMILES CNCCN1CCOc2ccc(cc12)N=C(N)c1cccs1 |w:14.15|
Show InChI InChI=1S/C16H20N4OS/c1-18-6-7-20-8-9-21-14-5-4-12(11-13(14)20)19-16(17)15-3-2-10-22-15/h2-5,10-11,18H,6-9H2,1H3,(H2,17,19)
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n/an/a 3.82E+3n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, endothelial


(Homo sapiens (Human))		BDBM111498
PNG
(US8618286, 24)
Show SMILES CCNCCN1CCSc2ccc(cc12)N=C(N)c1cccs1 |w:15.16|
Show InChI InChI=1S/C17H22N4S2/c1-2-19-7-8-21-9-11-23-15-6-5-13(12-14(15)21)20-17(18)16-4-3-10-22-16/h3-6,10,12,19H,2,7-9,11H2,1H3,(H2,18,20)
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n/an/a 4.45E+3n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, endothelial


(Homo sapiens (Human))		BDBM111490
PNG
(US8618286, 16)
Show SMILES NC(=Nc1ccc2N(CCNCCO)CCSc2c1)c1cccs1 |w:2.2|
Show InChI InChI=1S/C17H22N4OS2/c18-17(15-2-1-10-23-15)20-13-3-4-14-16(12-13)24-11-8-21(14)7-5-19-6-9-22/h1-4,10,12,19,22H,5-9,11H2,(H2,18,20)
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n/an/a 7.00E+3n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, inducible


(Homo sapiens (Human))		BDBM111483
PNG
(US8618286, 9)
Show SMILES CN(C)CCN1CCOc2ccc(cc12)N=C(N)c1cccs1 |w:15.16|
Show InChI InChI=1S/C17H22N4OS/c1-20(2)7-8-21-9-10-22-15-6-5-13(12-14(15)21)19-17(18)16-4-3-11-23-16/h3-6,11-12H,7-10H2,1-2H3,(H2,18,19)
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n/an/a 7.25E+3n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Recombinant human inducible NOS (iNOS) was produced in Baculovirus-infected Sf9 cells (ALEXIS). In a radiometric method, NO synthase activity was det...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, endothelial


(Homo sapiens (Human))		BDBM111500
PNG
(US8618286, 26)
Show SMILES NC(=Nc1ccc2SCCN(CCNCCO)c2c1)c1cccs1 |w:2.2|
Show InChI InChI=1S/C17H22N4OS2/c18-17(16-2-1-10-23-16)20-13-3-4-15-14(12-13)21(8-11-24-15)7-5-19-6-9-22/h1-4,10,12,19,22H,5-9,11H2,(H2,18,20)
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n/an/a 8.48E+3n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, endothelial


(Homo sapiens (Human))		BDBM111502
PNG
(US8618286, 28)
Show SMILES CNCCN1CCSc2ccc(cc12)N=C(N)c1cccs1 |w:14.15|
Show InChI InChI=1S/C16H20N4S2/c1-18-6-7-20-8-10-22-14-5-4-12(11-13(14)20)19-16(17)15-3-2-9-21-15/h2-5,9,11,18H,6-8,10H2,1H3,(H2,17,19)
PDB

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n/an/a 8.58E+3n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, endothelial


(Homo sapiens (Human))		BDBM111487
PNG
(US8618286, 13)
Show SMILES CN1CCCC1CCN1CCSc2cc(ccc12)N=C(N)c1cccs1 |w:18.20|
Show InChI InChI=1S/C20H26N4S2/c1-23-9-2-4-16(23)8-10-24-11-13-26-19-14-15(6-7-17(19)24)22-20(21)18-5-3-12-25-18/h3,5-7,12,14,16H,2,4,8-11,13H2,1H3,(H2,21,22)
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n/an/a 9.92E+3n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, endothelial


(Homo sapiens (Human))		BDBM111495
PNG
(US8618286, 21)
Show SMILES NC(=Nc1ccc2N(CCCN3CCCC3)CCSc2c1)c1cccs1 |w:2.2|
Show InChI InChI=1S/C20H26N4S2/c21-20(18-5-3-13-25-18)22-16-6-7-17-19(15-16)26-14-12-24(17)11-4-10-23-8-1-2-9-23/h3,5-7,13,15H,1-2,4,8-12,14H2,(H2,21,22)
PDB

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n/an/a 1.00E+4n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, endothelial


(Homo sapiens (Human))		BDBM111481
PNG
(US8618286, 7)
Show SMILES CCNCCN1CCOc2cc(ccc12)N=C(N)c1cccs1 |w:15.16|
Show InChI InChI=1S/C17H22N4OS/c1-2-19-7-8-21-9-10-22-15-12-13(5-6-14(15)21)20-17(18)16-4-3-11-23-16/h3-6,11-12,19H,2,7-10H2,1H3,(H2,18,20)
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n/an/a 1.04E+4n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, inducible


(Homo sapiens (Human))		BDBM111476
PNG
(US8618286, 2)
Show SMILES CN1CCCC1CCN1CCOc2cc(ccc12)N=C(N)c1cccs1 |w:18.20|
Show InChI InChI=1S/C20H26N4OS/c1-23-9-2-4-16(23)8-10-24-11-12-25-18-14-15(6-7-17(18)24)22-20(21)19-5-3-13-26-19/h3,5-7,13-14,16H,2,4,8-12H2,1H3,(H2,21,22)
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n/an/a 1.06E+4n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Recombinant human inducible NOS (iNOS) was produced in Baculovirus-infected Sf9 cells (ALEXIS). In a radiometric method, NO synthase activity was det...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, inducible


(Homo sapiens (Human))		BDBM111480
PNG
(US8618286, 6)
Show SMILES CN(C)CCN1CCOc2cc(ccc12)N=C(N)c1cccs1 |w:15.16|
Show InChI InChI=1S/C17H22N4OS/c1-20(2)7-8-21-9-10-22-15-12-13(5-6-14(15)21)19-17(18)16-4-3-11-23-16/h3-6,11-12H,7-10H2,1-2H3,(H2,18,19)
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n/an/a 1.09E+4n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Recombinant human inducible NOS (iNOS) was produced in Baculovirus-infected Sf9 cells (ALEXIS). In a radiometric method, NO synthase activity was det...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, endothelial


(Homo sapiens (Human))		BDBM111476
PNG
(US8618286, 2)
Show SMILES CN1CCCC1CCN1CCOc2cc(ccc12)N=C(N)c1cccs1 |w:18.20|
Show InChI InChI=1S/C20H26N4OS/c1-23-9-2-4-16(23)8-10-24-11-12-25-18-14-15(6-7-17(18)24)22-20(21)19-5-3-13-26-19/h3,5-7,13-14,16H,2,4,8-12H2,1H3,(H2,21,22)
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n/an/a 1.09E+4n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, endothelial


(Homo sapiens (Human))		BDBM111491
PNG
(US8618286, 17)
Show SMILES CN(CCN1CCSc2cc(ccc12)N=C(N)c1cccs1)CC(O)=O |w:14.15|
Show InChI InChI=1S/C18H22N4O2S2/c1-21(12-17(23)24)6-7-22-8-10-26-16-11-13(4-5-14(16)22)20-18(19)15-3-2-9-25-15/h2-5,9,11H,6-8,10,12H2,1H3,(H2,19,20)(H,23,24)
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n/an/a 1.09E+4n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, endothelial


(Homo sapiens (Human))		BDBM111488
PNG
(US8618286, 14)
Show SMILES NC(=Nc1ccc2N(CCN3CCCCC3)CCSc2c1)c1cccs1 |w:2.2|
Show InChI InChI=1S/C20H26N4S2/c21-20(18-5-4-13-25-18)22-16-6-7-17-19(15-16)26-14-12-24(17)11-10-23-8-2-1-3-9-23/h4-7,13,15H,1-3,8-12,14H2,(H2,21,22)
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n/an/a 1.15E+4n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, endothelial


(Homo sapiens (Human))		BDBM111496
PNG
(US8618286, 22)
Show SMILES CN(C)CCCN1CCSc2cc(ccc12)N=C(N)c1cccs1 |w:16.17|
Show InChI InChI=1S/C18H24N4S2/c1-21(2)8-4-9-22-10-12-24-17-13-14(6-7-15(17)22)20-18(19)16-5-3-11-23-16/h3,5-7,11,13H,4,8-10,12H2,1-2H3,(H2,19,20)
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n/an/a 1.21E+4n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, endothelial


(Homo sapiens (Human))		BDBM111492
PNG
(US8618286, 18)
Show SMILES NC(=Nc1ccc2N(CCN3CCC[C@H]3C(O)=O)CCSc2c1)c1cccs1 |r,w:2.2|
Show InChI InChI=1S/C20H24N4O2S2/c21-19(17-4-2-11-27-17)22-14-5-6-15-18(13-14)28-12-10-24(15)9-8-23-7-1-3-16(23)20(25)26/h2,4-6,11,13,16H,1,3,7-10,12H2,(H2,21,22)(H,25,26)/t16-/m0/s1
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n/an/a 1.26E+4n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, endothelial


(Homo sapiens (Human))		BDBM111477
PNG
(US8618286, 3)
Show SMILES NC(=Nc1ccc2N(CCN3CCCC3)C(=O)COc2c1)c1cccs1 |w:2.2|
Show InChI InChI=1S/C19H22N4O2S/c20-19(17-4-3-11-26-17)21-14-5-6-15-16(12-14)25-13-18(24)23(15)10-9-22-7-1-2-8-22/h3-6,11-12H,1-2,7-10,13H2,(H2,20,21)
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n/an/a 1.38E+4n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, endothelial


(Homo sapiens (Human))		BDBM111499
PNG
(US8618286, 25)
Show SMILES NC(=Nc1ccc2SCCN(CCN3CCCC3)c2c1)c1cccs1 |w:2.2|
Show InChI InChI=1S/C19H24N4S2/c20-19(18-4-3-12-24-18)21-15-5-6-17-16(14-15)23(11-13-25-17)10-9-22-7-1-2-8-22/h3-6,12,14H,1-2,7-11,13H2,(H2,20,21)
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n/an/a 1.81E+4n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, endothelial


(Homo sapiens (Human))		BDBM111497
PNG
(US8618286, 23)
Show SMILES CNCCCN1CCSc2cc(ccc12)N=C(N)c1cccs1 |w:15.16|
Show InChI InChI=1S/C17H22N4S2/c1-19-7-3-8-21-9-11-23-16-12-13(5-6-14(16)21)20-17(18)15-4-2-10-22-15/h2,4-6,10,12,19H,3,7-9,11H2,1H3,(H2,18,20)
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n/an/a 1.86E+4n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, endothelial


(Homo sapiens (Human))		BDBM111486
PNG
(US8618286, 12)
Show SMILES CN(C)CCN1CCSc2cc(ccc12)N=C(N)c1cccs1 |w:15.16|
Show InChI InChI=1S/C17H22N4S2/c1-20(2)7-8-21-9-11-23-16-12-13(5-6-14(16)21)19-17(18)15-4-3-10-22-15/h3-6,10,12H,7-9,11H2,1-2H3,(H2,18,19)
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n/an/a 1.91E+4n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, endothelial


(Homo sapiens (Human))		BDBM111489
PNG
(US8618286, 15)
Show SMILES CCN(CC)CCN1CCSc2cc(ccc12)N=C(N)c1cccs1 |w:17.18|
Show InChI InChI=1S/C19H26N4S2/c1-3-22(4-2)9-10-23-11-13-25-18-14-15(7-8-16(18)23)21-19(20)17-6-5-12-24-17/h5-8,12,14H,3-4,9-11,13H2,1-2H3,(H2,20,21)
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n/an/a 2.01E+4n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, endothelial


(Homo sapiens (Human))		BDBM111485
PNG
(US8618286, 11)
Show SMILES NC(=Nc1ccc2N(CCN3CCCC3)CCSc2c1)c1cccs1 |w:2.2|
Show InChI InChI=1S/C19H24N4S2/c20-19(17-4-3-12-24-17)21-15-5-6-16-18(14-15)25-13-11-23(16)10-9-22-7-1-2-8-22/h3-6,12,14H,1-2,7-11,13H2,(H2,20,21)
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n/an/a 2.44E+4n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, endothelial


(Homo sapiens (Human))		BDBM111478
PNG
(US8618286, 4)
Show SMILES NC(=Nc1ccc2N(CCN3CCCC3)CCOc2c1)c1cccs1 |w:2.2|
Show InChI InChI=1S/C19H24N4OS/c20-19(18-4-3-13-25-18)21-15-5-6-16-17(14-15)24-12-11-23(16)10-9-22-7-1-2-8-22/h3-6,13-14H,1-2,7-12H2,(H2,20,21)
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n/an/a 2.51E+4n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, inducible


(Homo sapiens (Human))		BDBM111487
PNG
(US8618286, 13)
Show SMILES CN1CCCC1CCN1CCSc2cc(ccc12)N=C(N)c1cccs1 |w:18.20|
Show InChI InChI=1S/C20H26N4S2/c1-23-9-2-4-16(23)8-10-24-11-13-26-19-14-15(6-7-17(19)24)22-20(21)18-5-3-12-25-18/h3,5-7,12,14,16H,2,4,8-11,13H2,1H3,(H2,21,22)
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n/an/a 3.31E+4n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Recombinant human inducible NOS (iNOS) was produced in Baculovirus-infected Sf9 cells (ALEXIS). In a radiometric method, NO synthase activity was det...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, endothelial


(Homo sapiens (Human))		BDBM111482
PNG
(US8618286, 8)
Show SMILES CNCCN1CCSc2cc(ccc12)N=C(N)c1cccs1 |w:14.15|
Show InChI InChI=1S/C16H20N4S2/c1-18-6-7-20-8-10-22-15-11-12(4-5-13(15)20)19-16(17)14-3-2-9-21-14/h2-5,9,11,18H,6-8,10H2,1H3,(H2,17,19)
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n/an/a 3.35E+4n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, endothelial


(Homo sapiens (Human))		BDBM111501
PNG
(US8618286, 27)
Show SMILES CN(C)CCN1CCSc2ccc(cc12)N=C(N)c1cccs1 |w:15.16|
Show InChI InChI=1S/C17H22N4S2/c1-20(2)7-8-21-9-11-23-15-6-5-13(12-14(15)21)19-17(18)16-4-3-10-22-16/h3-6,10,12H,7-9,11H2,1-2H3,(H2,18,19)
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n/an/a 3.49E+4n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, endothelial


(Homo sapiens (Human))		BDBM111483
PNG
(US8618286, 9)
Show SMILES CN(C)CCN1CCOc2ccc(cc12)N=C(N)c1cccs1 |w:15.16|
Show InChI InChI=1S/C17H22N4OS/c1-20(2)7-8-21-9-10-22-15-6-5-13(12-14(15)21)19-17(18)16-4-3-11-23-16/h3-6,11-12H,7-10H2,1-2H3,(H2,18,19)
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n/an/a 3.65E+4n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, inducible


(Homo sapiens (Human))		BDBM111489
PNG
(US8618286, 15)
Show SMILES CCN(CC)CCN1CCSc2cc(ccc12)N=C(N)c1cccs1 |w:17.18|
Show InChI InChI=1S/C19H26N4S2/c1-3-22(4-2)9-10-23-11-13-25-18-14-15(7-8-16(18)23)21-19(20)17-6-5-12-24-17/h5-8,12,14H,3-4,9-11,13H2,1-2H3,(H2,20,21)
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n/an/a 4.07E+4n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Recombinant human inducible NOS (iNOS) was produced in Baculovirus-infected Sf9 cells (ALEXIS). In a radiometric method, NO synthase activity was det...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, endothelial


(Homo sapiens (Human))		BDBM111480
PNG
(US8618286, 6)
Show SMILES CN(C)CCN1CCOc2cc(ccc12)N=C(N)c1cccs1 |w:15.16|
Show InChI InChI=1S/C17H22N4OS/c1-20(2)7-8-21-9-10-22-15-12-13(5-6-14(15)21)19-17(18)16-4-3-11-23-16/h3-6,11-12H,7-10H2,1-2H3,(H2,18,19)
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n/an/a 4.17E+4n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, inducible


(Homo sapiens (Human))		BDBM111499
PNG
(US8618286, 25)
Show SMILES NC(=Nc1ccc2SCCN(CCN3CCCC3)c2c1)c1cccs1 |w:2.2|
Show InChI InChI=1S/C19H24N4S2/c20-19(18-4-3-12-24-18)21-15-5-6-17-16(14-15)23(11-13-25-17)10-9-22-7-1-2-8-22/h3-6,12,14H,1-2,7-11,13H2,(H2,20,21)
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n/an/a 4.36E+4n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Recombinant human inducible NOS (iNOS) was produced in Baculovirus-infected Sf9 cells (ALEXIS). In a radiometric method, NO synthase activity was det...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, endothelial


(Homo sapiens (Human))		BDBM111503
PNG
(US8618286, 29)
Show SMILES NC(=Nc1ccc2SCCN(C3CCNCC3)c2c1)c1cccs1 |w:2.2|
Show InChI InChI=1S/C18H22N4S2/c19-18(17-2-1-10-23-17)21-13-3-4-16-15(12-13)22(9-11-24-16)14-5-7-20-8-6-14/h1-4,10,12,14,20H,5-9,11H2,(H2,19,21)
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n/an/a 4.36E+4n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, endothelial


(Homo sapiens (Human))		BDBM111494
PNG
(US8618286, 20)
Show SMILES CNCCN1CCSc2cc(ccc12)N=C(N)c1ccco1 |w:14.15|
Show InChI InChI=1S/C16H20N4OS/c1-18-6-7-20-8-10-22-15-11-12(4-5-13(15)20)19-16(17)14-3-2-9-21-14/h2-5,9,11,18H,6-8,10H2,1H3,(H2,17,19)
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n/an/a 4.64E+4n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, endothelial


(Homo sapiens (Human))		BDBM111479
PNG
(US8618286, 5)
Show SMILES CN(C)CCN1C(=O)COc2cc(ccc12)N=C(N)c1cccs1 |w:16.17|
Show InChI InChI=1S/C17H20N4O2S/c1-20(2)7-8-21-13-6-5-12(10-14(13)23-11-16(21)22)19-17(18)15-4-3-9-24-15/h3-6,9-10H,7-8,11H2,1-2H3,(H2,18,19)
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n/an/a 4.70E+4n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, inducible


(Homo sapiens (Human))		BDBM111495
PNG
(US8618286, 21)
Show SMILES NC(=Nc1ccc2N(CCCN3CCCC3)CCSc2c1)c1cccs1 |w:2.2|
Show InChI InChI=1S/C20H26N4S2/c21-20(18-5-3-13-25-18)22-16-6-7-17-19(15-16)26-14-12-24(17)11-4-10-23-8-1-2-9-23/h3,5-7,13,15H,1-2,4,8-12,14H2,(H2,21,22)
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n/an/a 4.96E+4n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Recombinant human inducible NOS (iNOS) was produced in Baculovirus-infected Sf9 cells (ALEXIS). In a radiometric method, NO synthase activity was det...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, inducible


(Homo sapiens (Human))		BDBM111490
PNG
(US8618286, 16)
Show SMILES NC(=Nc1ccc2N(CCNCCO)CCSc2c1)c1cccs1 |w:2.2|
Show InChI InChI=1S/C17H22N4OS2/c18-17(15-2-1-10-23-15)20-13-3-4-14-16(12-13)24-11-8-21(14)7-5-19-6-9-22/h1-4,10,12,19,22H,5-9,11H2,(H2,18,20)
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n/an/a 5.87E+4n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Recombinant human inducible NOS (iNOS) was produced in Baculovirus-infected Sf9 cells (ALEXIS). In a radiometric method, NO synthase activity was det...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, inducible


(Homo sapiens (Human))		BDBM111500
PNG
(US8618286, 26)
Show SMILES NC(=Nc1ccc2SCCN(CCNCCO)c2c1)c1cccs1 |w:2.2|
Show InChI InChI=1S/C17H22N4OS2/c18-17(16-2-1-10-23-16)20-13-3-4-15-14(12-13)21(8-11-24-15)7-5-19-6-9-22/h1-4,10,12,19,22H,5-9,11H2,(H2,18,20)
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n/an/a 6.01E+4n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Recombinant human inducible NOS (iNOS) was produced in Baculovirus-infected Sf9 cells (ALEXIS). In a radiometric method, NO synthase activity was det...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, inducible


(Homo sapiens (Human))		BDBM111486
PNG
(US8618286, 12)
Show SMILES CN(C)CCN1CCSc2cc(ccc12)N=C(N)c1cccs1 |w:15.16|
Show InChI InChI=1S/C17H22N4S2/c1-20(2)7-8-21-9-11-23-16-12-13(5-6-14(16)21)19-17(18)15-4-3-10-22-15/h3-6,10,12H,7-9,11H2,1-2H3,(H2,18,19)
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n/an/a 6.29E+4n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Recombinant human inducible NOS (iNOS) was produced in Baculovirus-infected Sf9 cells (ALEXIS). In a radiometric method, NO synthase activity was det...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, inducible


(Homo sapiens (Human))		BDBM111501
PNG
(US8618286, 27)
Show SMILES CN(C)CCN1CCSc2ccc(cc12)N=C(N)c1cccs1 |w:15.16|
Show InChI InChI=1S/C17H22N4S2/c1-20(2)7-8-21-9-11-23-15-6-5-13(12-14(15)21)19-17(18)16-4-3-10-22-16/h3-6,10,12H,7-9,11H2,1-2H3,(H2,18,19)
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n/an/a 6.65E+4n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Recombinant human inducible NOS (iNOS) was produced in Baculovirus-infected Sf9 cells (ALEXIS). In a radiometric method, NO synthase activity was det...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, inducible


(Homo sapiens (Human))		BDBM111482
PNG
(US8618286, 8)
Show SMILES CNCCN1CCSc2cc(ccc12)N=C(N)c1cccs1 |w:14.15|
Show InChI InChI=1S/C16H20N4S2/c1-18-6-7-20-8-10-22-15-11-12(4-5-13(15)20)19-16(17)14-3-2-9-21-14/h2-5,9,11,18H,6-8,10H2,1H3,(H2,17,19)
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n/an/a 7.06E+4n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Recombinant human inducible NOS (iNOS) was produced in Baculovirus-infected Sf9 cells (ALEXIS). In a radiometric method, NO synthase activity was det...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, inducible


(Homo sapiens (Human))		BDBM111503
PNG
(US8618286, 29)
Show SMILES NC(=Nc1ccc2SCCN(C3CCNCC3)c2c1)c1cccs1 |w:2.2|
Show InChI InChI=1S/C18H22N4S2/c19-18(17-2-1-10-23-17)21-13-3-4-16-15(12-13)22(9-11-24-16)14-5-7-20-8-6-14/h1-4,10,12,14,20H,5-9,11H2,(H2,19,21)
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n/an/a 7.68E+4n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Recombinant human inducible NOS (iNOS) was produced in Baculovirus-infected Sf9 cells (ALEXIS). In a radiometric method, NO synthase activity was det...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, inducible


(Homo sapiens (Human))		BDBM111498
PNG
(US8618286, 24)
Show SMILES CCNCCN1CCSc2ccc(cc12)N=C(N)c1cccs1 |w:15.16|
Show InChI InChI=1S/C17H22N4S2/c1-2-19-7-8-21-9-11-23-15-6-5-13(12-14(15)21)20-17(18)16-4-3-10-22-16/h3-6,10,12,19H,2,7-9,11H2,1H3,(H2,18,20)
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n/an/a 8.23E+4n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Recombinant human inducible NOS (iNOS) was produced in Baculovirus-infected Sf9 cells (ALEXIS). In a radiometric method, NO synthase activity was det...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, endothelial


(Homo sapiens (Human))		BDBM111475
PNG
(US8618286, 1)
Show SMILES CN1CCCC1CCN1C(=O)COc2cc(ccc12)N=C(N)c1cccs1 |w:19.21|
Show InChI InChI=1S/C20H24N4O2S/c1-23-9-2-4-15(23)8-10-24-16-7-6-14(12-17(16)26-13-19(24)25)22-20(21)18-5-3-11-27-18/h3,5-7,11-12,15H,2,4,8-10,13H2,1H3,(H2,21,22)
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n/an/a 8.72E+4n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, endothelial


(Homo sapiens (Human))		BDBM111493
PNG
(US8618286, 19)
Show SMILES CN(C)CCN1CCSc2cc(ccc12)N=C(N)c1ccco1 |w:15.16|
Show InChI InChI=1S/C17H22N4OS/c1-20(2)7-8-21-9-11-23-16-12-13(5-6-14(16)21)19-17(18)15-4-3-10-22-15/h3-6,10,12H,7-9,11H2,1-2H3,(H2,18,19)
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n/an/a 9.47E+4n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, inducible


(Homo sapiens (Human))		BDBM111475
PNG
(US8618286, 1)
Show SMILES CN1CCCC1CCN1C(=O)COc2cc(ccc12)N=C(N)c1cccs1 |w:19.21|
Show InChI InChI=1S/C20H24N4O2S/c1-23-9-2-4-15(23)8-10-24-16-7-6-14(12-17(16)26-13-19(24)25)22-20(21)18-5-3-11-27-18/h3,5-7,11-12,15H,2,4,8-10,13H2,1H3,(H2,21,22)
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n/an/a>1.00E+5n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Recombinant human inducible NOS (iNOS) was produced in Baculovirus-infected Sf9 cells (ALEXIS). In a radiometric method, NO synthase activity was det...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, inducible


(Homo sapiens (Human))		BDBM111479
PNG
(US8618286, 5)
Show SMILES CN(C)CCN1C(=O)COc2cc(ccc12)N=C(N)c1cccs1 |w:16.17|
Show InChI InChI=1S/C17H20N4O2S/c1-20(2)7-8-21-13-6-5-12(10-14(13)23-11-16(21)22)19-17(18)15-4-3-9-24-15/h3-6,9-10H,7-8,11H2,1-2H3,(H2,18,19)
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n/an/a>1.00E+5n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Recombinant human inducible NOS (iNOS) was produced in Baculovirus-infected Sf9 cells (ALEXIS). In a radiometric method, NO synthase activity was det...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, inducible


(Homo sapiens (Human))		BDBM111481
PNG
(US8618286, 7)
Show SMILES CCNCCN1CCOc2cc(ccc12)N=C(N)c1cccs1 |w:15.16|
Show InChI InChI=1S/C17H22N4OS/c1-2-19-7-8-21-9-10-22-15-12-13(5-6-14(15)21)20-17(18)16-4-3-11-23-16/h3-6,11-12,19H,2,7-10H2,1H3,(H2,18,20)
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n/an/a>1.00E+5n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Recombinant human inducible NOS (iNOS) was produced in Baculovirus-infected Sf9 cells (ALEXIS). In a radiometric method, NO synthase activity was det...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, inducible


(Homo sapiens (Human))		BDBM111496
PNG
(US8618286, 22)
Show SMILES CN(C)CCCN1CCSc2cc(ccc12)N=C(N)c1cccs1 |w:16.17|
Show InChI InChI=1S/C18H24N4S2/c1-21(2)8-4-9-22-10-12-24-17-13-14(6-7-15(17)22)20-18(19)16-5-3-11-23-16/h3,5-7,11,13H,4,8-10,12H2,1-2H3,(H2,19,20)
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n/an/a 1.15E+5n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Recombinant human inducible NOS (iNOS) was produced in Baculovirus-infected Sf9 cells (ALEXIS). In a radiometric method, NO synthase activity was det...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, inducible


(Homo sapiens (Human))		BDBM111485
PNG
(US8618286, 11)
Show SMILES NC(=Nc1ccc2N(CCN3CCCC3)CCSc2c1)c1cccs1 |w:2.2|
Show InChI InChI=1S/C19H24N4S2/c20-19(17-4-3-12-24-17)21-15-5-6-16-18(14-15)25-13-11-23(16)10-9-22-7-1-2-8-22/h3-6,12,14H,1-2,7-11,13H2,(H2,20,21)
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n/an/a 1.17E+5n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Recombinant human inducible NOS (iNOS) was produced in Baculovirus-infected Sf9 cells (ALEXIS). In a radiometric method, NO synthase activity was det...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, inducible


(Homo sapiens (Human))		BDBM111493
PNG
(US8618286, 19)
Show SMILES CN(C)CCN1CCSc2cc(ccc12)N=C(N)c1ccco1 |w:15.16|
Show InChI InChI=1S/C17H22N4OS/c1-20(2)7-8-21-9-11-23-16-12-13(5-6-14(16)21)19-17(18)15-4-3-10-22-15/h3-6,10,12H,7-9,11H2,1-2H3,(H2,18,19)
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n/an/a 1.36E+5n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Recombinant human inducible NOS (iNOS) was produced in Baculovirus-infected Sf9 cells (ALEXIS). In a radiometric method, NO synthase activity was det...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, inducible


(Homo sapiens (Human))		BDBM111497
PNG
(US8618286, 23)
Show SMILES CNCCCN1CCSc2cc(ccc12)N=C(N)c1cccs1 |w:15.16|
Show InChI InChI=1S/C17H22N4S2/c1-19-7-3-8-21-9-11-23-16-12-13(5-6-14(16)21)20-17(18)15-4-2-10-22-15/h2,4-6,10,12,19H,3,7-9,11H2,1H3,(H2,18,20)
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n/an/a 1.72E+5n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Recombinant human inducible NOS (iNOS) was produced in Baculovirus-infected Sf9 cells (ALEXIS). In a radiometric method, NO synthase activity was det...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, inducible


(Homo sapiens (Human))		BDBM111488
PNG
(US8618286, 14)
Show SMILES NC(=Nc1ccc2N(CCN3CCCCC3)CCSc2c1)c1cccs1 |w:2.2|
Show InChI InChI=1S/C20H26N4S2/c21-20(18-5-4-13-25-18)22-16-6-7-17-19(15-16)26-14-12-24(17)11-10-23-8-2-1-3-9-23/h4-7,13,15H,1-3,8-12,14H2,(H2,21,22)
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n/an/a 1.72E+5n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Recombinant human inducible NOS (iNOS) was produced in Baculovirus-infected Sf9 cells (ALEXIS). In a radiometric method, NO synthase activity was det...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, inducible


(Homo sapiens (Human))		BDBM111491
PNG
(US8618286, 17)
Show SMILES CN(CCN1CCSc2cc(ccc12)N=C(N)c1cccs1)CC(O)=O |w:14.15|
Show InChI InChI=1S/C18H22N4O2S2/c1-21(12-17(23)24)6-7-22-8-10-26-16-11-13(4-5-14(16)22)20-18(19)15-3-2-9-25-15/h2-5,9,11H,6-8,10,12H2,1H3,(H2,19,20)(H,23,24)
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n/an/a 2.41E+5n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Recombinant human inducible NOS (iNOS) was produced in Baculovirus-infected Sf9 cells (ALEXIS). In a radiometric method, NO synthase activity was det...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, inducible


(Homo sapiens (Human))		BDBM111494
PNG
(US8618286, 20)
Show SMILES CNCCN1CCSc2cc(ccc12)N=C(N)c1ccco1 |w:14.15|
Show InChI InChI=1S/C16H20N4OS/c1-18-6-7-20-8-10-22-15-11-12(4-5-13(15)20)19-16(17)14-3-2-9-21-14/h2-5,9,11,18H,6-8,10H2,1H3,(H2,17,19)
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n/an/a 2.68E+5n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Recombinant human inducible NOS (iNOS) was produced in Baculovirus-infected Sf9 cells (ALEXIS). In a radiometric method, NO synthase activity was det...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, inducible


(Homo sapiens (Human))		BDBM111492
PNG
(US8618286, 18)
Show SMILES NC(=Nc1ccc2N(CCN3CCC[C@H]3C(O)=O)CCSc2c1)c1cccs1 |r,w:2.2|
Show InChI InChI=1S/C20H24N4O2S2/c21-19(17-4-2-11-27-17)22-14-5-6-15-18(13-14)28-12-10-24(15)9-8-23-7-1-3-16(23)20(25)26/h2,4-6,11,13,16H,1,3,7-10,12H2,(H2,21,22)(H,25,26)/t16-/m0/s1
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n/an/a 3.41E+5n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Recombinant human inducible NOS (iNOS) was produced in Baculovirus-infected Sf9 cells (ALEXIS). In a radiometric method, NO synthase activity was det...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
Nitric oxide synthase, inducible


(Homo sapiens (Human))		BDBM111502
PNG
(US8618286, 28)
Show SMILES CNCCN1CCSc2ccc(cc12)N=C(N)c1cccs1 |w:14.15|
Show InChI InChI=1S/C16H20N4S2/c1-18-6-7-20-8-10-22-14-5-4-12(11-13(14)20)19-16(17)15-3-2-9-21-15/h2-5,9,11,18H,6-8,10H2,1H3,(H2,17,19)
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n/an/a 3.48E+5n/an/an/an/an/an/a



NeurAxon, Inc.

US Patent


Assay Description
Recombinant human inducible NOS (iNOS) was produced in Baculovirus-infected Sf9 cells (ALEXIS). In a radiometric method, NO synthase activity was det...

US Patent US8618286 (2013)


BindingDB Entry DOI: 10.7270/Q2C53JH7
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%