null
SMILES: NC(=Nc1ccc2N(CCN3CCCC3)C(=O)COc2c1)c1cccs1
InChI Key: InChIKey=LFKLDLHIJLFFAI-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Nitric oxide synthase, brain (Homo sapiens (Human)) | BDBM111477 (US8618286, 3) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 850 | n/a | n/a | n/a | n/a | n/a | n/a |
NeurAxon, Inc. US Patent | Assay Description Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes... | US Patent US8618286 (2013) BindingDB Entry DOI: 10.7270/Q2C53JH7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitric oxide synthase, inducible (Homo sapiens (Human)) | BDBM111477 (US8618286, 3) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
NeurAxon, Inc. US Patent | Assay Description Recombinant human inducible NOS (iNOS) was produced in Baculovirus-infected Sf9 cells (ALEXIS). In a radiometric method, NO synthase activity was det... | US Patent US8618286 (2013) BindingDB Entry DOI: 10.7270/Q2C53JH7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nitric oxide synthase, endothelial (Homo sapiens (Human)) | BDBM111477 (US8618286, 3) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.38E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
NeurAxon, Inc. US Patent | Assay Description Primary stock solutions of test compounds at a concentration of 6 mM were prepared from the 2 to 5 mg powder. The primary stock solutions of each tes... | US Patent US8618286 (2013) BindingDB Entry DOI: 10.7270/Q2C53JH7 | |||||||||||
More data for this Ligand-Target Pair |