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Patent code US8921373

Compile Data Set for Download or QSAR
Found 25 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM141515
PNG
(US8921373, ACU)
Show SMILES COC1CN(CCN1C(=O)Nc1nc2ccc(F)cc2s1)c1ncc(C[C@@H](O)CO)cc1Cl |r|
Show InChI InChI=1S/C21H23ClFN5O4S/c1-32-18-10-27(19-15(22)7-12(9-24-19)6-14(30)11-29)4-5-28(18)21(31)26-20-25-16-3-2-13(23)8-17(16)33-20/h2-3,7-9,14,18,29-30H,4-6,10-11H2,1H3,(H,25,26,31)/t14-,18?/m1/s1
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US Patent
n/an/a 1n/an/an/an/a7.4n/a



Shionogi & Co., Ltd.

US Patent


Assay Description
Two days prior to performing this assay, cells are seeded on poly-D-lysine-coated 96-well clear-bottom black plates (commercially available from Bect...


US Patent US8921373 (2014)


BindingDB Entry DOI: 10.7270/Q28051BW
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM141532
PNG
(US8921373, AAD)
Show SMILES OCC(O)Cc1cnc(C2CCN(CC2)C(=O)Nc2nc3cc(F)ccc3s2)c(Cl)c1
Show InChI InChI=1S/C21H22ClFN4O3S/c22-16-8-12(7-15(29)11-28)10-24-19(16)13-3-5-27(6-4-13)21(30)26-20-25-17-9-14(23)1-2-18(17)31-20/h1-2,8-10,13,15,28-29H,3-7,11H2,(H,25,26,30)
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n/an/a 5n/an/an/an/a7.4n/a



Shionogi & Co., Ltd.

US Patent


Assay Description
Two days prior to performing this assay, cells are seeded on poly-D-lysine-coated 96-well clear-bottom black plates (commercially available from Bect...


US Patent US8921373 (2014)


BindingDB Entry DOI: 10.7270/Q28051BW
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM141534
PNG
(US8921373, ADK)
Show SMILES C[C@@H]1CC(F)(CCN1C(=O)Nc1nc2cc(Cl)ccc2s1)c1ncc(C[C@H](O)CO)cc1F |r|
Show InChI InChI=1S/C22H23ClF2N4O3S/c1-12-9-22(25,19-16(24)7-13(10-26-19)6-15(31)11-30)4-5-29(12)21(32)28-20-27-17-8-14(23)2-3-18(17)33-20/h2-3,7-8,10,12,15,30-31H,4-6,9,11H2,1H3,(H,27,28,32)/t12-,15+,22?/m1/s1
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n/an/a 8n/an/an/an/a7.4n/a



Shionogi & Co., Ltd.

US Patent


Assay Description
Two days prior to performing this assay, cells are seeded in poly-D-lysine-coated 96-well clear-bottom black plates (50,000 cells/well) in growth med...


US Patent US8921373 (2014)


BindingDB Entry DOI: 10.7270/Q28051BW
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM141531
PNG
(US8921373, AAC)
Show SMILES OCC(O)Cc1cnc(C2=CCN(CC2)C(=O)Nc2ccc(c(Cl)c2)C(F)(F)F)c(Cl)c1 |t:9|
Show InChI InChI=1S/C21H20Cl2F3N3O3/c22-17-9-14(1-2-16(17)21(24,25)26)28-20(32)29-5-3-13(4-6-29)19-18(23)8-12(10-27-19)7-15(31)11-30/h1-3,8-10,15,30-31H,4-7,11H2,(H,28,32)
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n/an/a 10n/an/an/an/a7.4n/a



Shionogi & Co., Ltd.

US Patent


Assay Description
Two days prior to performing this assay, cells are seeded on poly-D-lysine-coated 96-well clear-bottom black plates (commercially available from Bect...


US Patent US8921373 (2014)


BindingDB Entry DOI: 10.7270/Q28051BW
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM141530
PNG
(US8921373, AAB)
Show SMILES OCC(O)Cc1cnc(C2=CCN(CC2)C(=O)Nc2ccc(cc2)C(F)(F)F)c(Cl)c1 |t:9|
Show InChI InChI=1S/C21H21ClF3N3O3/c22-18-10-13(9-17(30)12-29)11-26-19(18)14-5-7-28(8-6-14)20(31)27-16-3-1-15(2-4-16)21(23,24)25/h1-5,10-11,17,29-30H,6-9,12H2,(H,27,31)
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n/an/a 12n/an/an/an/a7.4n/a



Shionogi & Co., Ltd.

US Patent


Assay Description
Two days prior to performing this assay, cells are seeded on poly-D-lysine-coated 96-well clear-bottom black plates (commercially available from Bect...


US Patent US8921373 (2014)


BindingDB Entry DOI: 10.7270/Q28051BW
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM141511
PNG
(US8921373, AAN)
Show SMILES OC[C@H](O)Cc1cnc(C2=CCN(CC2)C(=O)Nc2ccc(OC(F)(F)F)c(Cl)c2)c(Cl)c1 |r,t:9|
Show InChI InChI=1S/C21H20Cl2F3N3O4/c22-16-9-14(1-2-18(16)33-21(24,25)26)28-20(32)29-5-3-13(4-6-29)19-17(23)8-12(10-27-19)7-15(31)11-30/h1-3,8-10,15,30-31H,4-7,11H2,(H,28,32)/t15-/m1/s1
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n/an/a 17n/an/an/an/a7.4n/a



Shionogi & Co., Ltd.

US Patent


Assay Description
Two days prior to performing this assay, cells are seeded on poly-D-lysine-coated 96-well clear-bottom black plates (commercially available from Bect...


US Patent US8921373 (2014)


BindingDB Entry DOI: 10.7270/Q28051BW
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM141516
PNG
(US8921373, 3)
Show SMILES C[C@@H]1CN(CCN1C(=O)Nc1nc2ccc(F)cc2s1)c1ncccc1Cl |r|
Show InChI InChI=1S/C18H17ClFN5OS/c1-11-10-24(16-13(19)3-2-6-21-16)7-8-25(11)18(26)23-17-22-14-5-4-12(20)9-15(14)27-17/h2-6,9,11H,7-8,10H2,1H3,(H,22,23,26)/t11-/m1/s1
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n/an/a 24n/an/an/an/a7.4n/a



Shionogi & Co., Ltd.

US Patent


Assay Description
Two days prior to performing this assay, cells are seeded on poly-D-lysine-coated 96-well clear-bottom black plates (commercially available from Bect...


US Patent US8921373 (2014)


BindingDB Entry DOI: 10.7270/Q28051BW
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM141523
PNG
(US8921373, 8 | US9365563, 200 | US9878991, Compoun...)
Show SMILES FC(F)(F)c1ccc(NC(=O)N2CCC(=CC2)c2ncccc2Cl)cc1 |c:14|
Show InChI InChI=1S/C18H15ClF3N3O/c19-15-2-1-9-23-16(15)12-7-10-25(11-8-12)17(26)24-14-5-3-13(4-6-14)18(20,21)22/h1-7,9H,8,10-11H2,(H,24,26)
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n/an/a 32n/an/an/an/a7.4n/a



Shionogi & Co., Ltd.

US Patent


Assay Description
Two days prior to performing this assay, cells are seeded on poly-D-lysine-coated 96-well clear-bottom black plates (commercially available from Bect...


US Patent US8921373 (2014)


BindingDB Entry DOI: 10.7270/Q28051BW
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM141529
PNG
(US8921373, AAA)
Show SMILES OCC(O)Cc1cnc(C2=CCN(CC2)C(=O)Nc2ccc(cn2)C(F)(F)F)c(Cl)c1 |t:9|
Show InChI InChI=1S/C20H20ClF3N4O3/c21-16-8-12(7-15(30)11-29)9-26-18(16)13-3-5-28(6-4-13)19(31)27-17-2-1-14(10-25-17)20(22,23)24/h1-3,8-10,15,29-30H,4-7,11H2,(H,25,27,31)
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n/an/a 38n/an/an/an/a7.4n/a



Shionogi & Co., Ltd.

US Patent


Assay Description
Two days prior to performing this assay, cells are seeded on poly-D-lysine-coated 96-well clear-bottom black plates (commercially available from Bect...


US Patent US8921373 (2014)


BindingDB Entry DOI: 10.7270/Q28051BW
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM141535
PNG
(US8921373, AAW)
Show SMILES Cc1cc(NC(=O)N2CCC(=CC2)c2ncc(C[C@H](O)CO)cc2Cl)ccc1C(F)(F)F |r,c:10|
Show InChI InChI=1S/C22H23ClF3N3O3/c1-13-8-16(2-3-18(13)22(24,25)26)28-21(32)29-6-4-15(5-7-29)20-19(23)10-14(11-27-20)9-17(31)12-30/h2-4,8,10-11,17,30-31H,5-7,9,12H2,1H3,(H,28,32)/t17-/m0/s1
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n/an/a 40n/an/an/an/a7.4n/a



Shionogi & Co., Ltd.

US Patent


Assay Description
Two days prior to performing this assay, cells are seeded in poly-D-lysine-coated 96-well clear-bottom black plates (50,000 cells/well) in growth med...


US Patent US8921373 (2014)


BindingDB Entry DOI: 10.7270/Q28051BW
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM141513
PNG
(US8921373, ABL)
Show SMILES OC[C@H](O)C(F)(F)c1cnc(C2=CCN(CC2)C(=O)Nc2ccc(OC(F)(F)F)cn2)c(Cl)c1 |r,t:11|
Show InChI InChI=1S/C20H18ClF5N4O4/c21-14-7-12(19(22,23)15(32)10-31)8-28-17(14)11-3-5-30(6-4-11)18(33)29-16-2-1-13(9-27-16)34-20(24,25)26/h1-3,7-9,15,31-32H,4-6,10H2,(H,27,29,33)/t15-/m0/s1
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n/an/a 46n/an/an/an/a7.4n/a



Shionogi & Co., Ltd.

US Patent


Assay Description
Two days prior to performing this assay, cells are seeded on poly-D-lysine-coated 96-well clear-bottom black plates (commercially available from Bect...


US Patent US8921373 (2014)


BindingDB Entry DOI: 10.7270/Q28051BW
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM141533
PNG
(US8921373, ACR)
Show SMILES Cc1cc(NC(=O)N2CCC(F)(CC2)c2ncc(C[C@H](O)CO)cc2F)ccc1OC(F)(F)F |r|
Show InChI InChI=1S/C22H24F5N3O4/c1-13-8-15(2-3-18(13)34-22(25,26)27)29-20(33)30-6-4-21(24,5-7-30)19-17(23)10-14(11-28-19)9-16(32)12-31/h2-3,8,10-11,16,31-32H,4-7,9,12H2,1H3,(H,29,33)/t16-/m0/s1
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n/an/a 46n/an/an/an/a7.4n/a



Shionogi & Co., Ltd.

US Patent


Assay Description
Two days prior to performing this assay, cells are seeded in poly-D-lysine-coated 96-well clear-bottom black plates (50,000 cells/well) in growth med...


US Patent US8921373 (2014)


BindingDB Entry DOI: 10.7270/Q28051BW
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM141512
PNG
(US8921373, 1 | US8921373, 9)
Show SMILES FC(F)(F)c1ccc(NC(=O)N2CCC(=CC2)c2ncccc2Cl)cc1Cl |c:14|
Show InChI InChI=1S/C18H14Cl2F3N3O/c19-14-2-1-7-24-16(14)11-5-8-26(9-6-11)17(27)25-12-3-4-13(15(20)10-12)18(21,22)23/h1-5,7,10H,6,8-9H2,(H,25,27)
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n/an/a 77n/an/an/an/a7.4n/a



Shionogi & Co., Ltd.

US Patent


Assay Description
Two days prior to performing this assay, cells are seeded on poly-D-lysine-coated 96-well clear-bottom black plates (commercially available from Bect...


US Patent US8921373 (2014)


BindingDB Entry DOI: 10.7270/Q28051BW
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM141526
PNG
(US8921373, 11)
Show SMILES Cc1cc(NC(=O)N2CCC(F)(CC2)c2ncccc2F)ccc1OC(F)(F)F
Show InChI InChI=1S/C19H18F5N3O2/c1-12-11-13(4-5-15(12)29-19(22,23)24)26-17(28)27-9-6-18(21,7-10-27)16-14(20)3-2-8-25-16/h2-5,8,11H,6-7,9-10H2,1H3,(H,26,28)
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n/an/a 100n/an/an/an/a7.4n/a



Shionogi & Co., Ltd.

US Patent


Assay Description
Two days prior to performing this assay, cells are seeded in poly-D-lysine-coated 96-well clear-bottom black plates (50,000 cells/well) in growth med...


US Patent US8921373 (2014)


BindingDB Entry DOI: 10.7270/Q28051BW
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM141527
PNG
(US8921373, AEF)
Show SMILES OC[C@@H](O)Cc1cnc(c(Cl)c1)C1(F)CCN(CC1)C(=O)Nc1nc2ccc(F)cc2s1 |r|
Show InChI InChI=1S/C21H21ClF2N4O3S/c22-15-8-12(7-14(30)11-29)10-25-18(15)21(24)3-5-28(6-4-21)20(31)27-19-26-16-2-1-13(23)9-17(16)32-19/h1-2,8-10,14,29-30H,3-7,11H2,(H,26,27,31)/t14-/m0/s1
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n/an/a 116n/an/an/an/a7.4n/a



Shionogi & Co., Ltd.

US Patent


Assay Description
Two days prior to performing this assay, cells are seeded in poly-D-lysine-coated 96-well clear-bottom black plates (50,000 cells/well) in growth med...


US Patent US8921373 (2014)


BindingDB Entry DOI: 10.7270/Q28051BW
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM141512
PNG
(US8921373, 1 | US8921373, 9)
Show SMILES FC(F)(F)c1ccc(NC(=O)N2CCC(=CC2)c2ncccc2Cl)cc1Cl |c:14|
Show InChI InChI=1S/C18H14Cl2F3N3O/c19-14-2-1-7-24-16(14)11-5-8-26(9-6-11)17(27)25-12-3-4-13(15(20)10-12)18(21,22)23/h1-5,7,10H,6,8-9H2,(H,25,27)
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n/an/a 139n/an/an/an/a7.4n/a



Shionogi & Co., Ltd.

US Patent


Assay Description
Two days prior to performing this assay, cells are seeded on poly-D-lysine-coated 96-well clear-bottom black plates (commercially available from Bect...


US Patent US8921373 (2014)


BindingDB Entry DOI: 10.7270/Q28051BW
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM141517
PNG
(US8921373, ABE)
Show SMILES OC[C@@H](O)[C@@H](O)c1cnc(c(Cl)c1)C1(F)CCN(CC1)C(=O)Nc1ccc(cn1)C(F)(F)F |r|
Show InChI InChI=1S/C20H21ClF4N4O4/c21-13-7-11(16(32)14(31)10-30)8-27-17(13)19(22)3-5-29(6-4-19)18(33)28-15-2-1-12(9-26-15)20(23,24)25/h1-2,7-9,14,16,30-32H,3-6,10H2,(H,26,28,33)/t14-,16+/m1/s1
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n/an/a 143n/an/an/an/a7.4n/a



Shionogi & Co., Ltd.

US Patent


Assay Description
Two days prior to performing this assay, cells are seeded on poly-D-lysine-coated 96-well clear-bottom black plates (commercially available from Bect...


US Patent US8921373 (2014)


BindingDB Entry DOI: 10.7270/Q28051BW
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM141518
PNG
(US8921373, 5 | US9365563, 204 | US9878991, Compoun...)
Show SMILES FC(F)(F)c1ccc(NC(=O)N2CCC(F)(CC2)c2ncccc2Cl)nc1
Show InChI InChI=1S/C17H15ClF4N4O/c18-12-2-1-7-23-14(12)16(19)5-8-26(9-6-16)15(27)25-13-4-3-11(10-24-13)17(20,21)22/h1-4,7,10H,5-6,8-9H2,(H,24,25,27)
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n/an/a 154n/an/an/an/a7.4n/a



Shionogi & Co., Ltd.

US Patent


Assay Description
Two days prior to performing this assay, cells are seeded on poly-D-lysine-coated 96-well clear-bottom black plates (commercially available from Bect...


US Patent US8921373 (2014)


BindingDB Entry DOI: 10.7270/Q28051BW
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM141519
PNG
(US8921373, ABD)
Show SMILES OC[C@@H](O)[C@@H](O)c1cnc(c(Cl)c1)C1(F)CCN(CC1)C(=O)Nc1nc2ccc(cc2s1)C(F)(F)F |r|
Show InChI InChI=1S/C22H21ClF4N4O4S/c23-13-7-11(17(34)15(33)10-32)9-28-18(13)21(24)3-5-31(6-4-21)20(35)30-19-29-14-2-1-12(22(25,26)27)8-16(14)36-19/h1-2,7-9,15,17,32-34H,3-6,10H2,(H,29,30,35)/t15-,17+/m1/s1
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n/an/a 171n/an/an/an/a7.4n/a



Shionogi & Co., Ltd.

US Patent


Assay Description
Two days prior to performing this assay, cells are seeded on poly-D-lysine-coated 96-well clear-bottom black plates (commercially available from Bect...


US Patent US8921373 (2014)


BindingDB Entry DOI: 10.7270/Q28051BW
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM141514
PNG
(US8921373, 2 | US8921373, 7 | US9365563, 201 | US9...)
Show SMILES FC(F)(F)c1ccc(NC(=O)N2CCC(=CC2)c2ncccc2Cl)nc1 |c:14|
Show InChI InChI=1S/C17H14ClF3N4O/c18-13-2-1-7-22-15(13)11-5-8-25(9-6-11)16(26)24-14-4-3-12(10-23-14)17(19,20)21/h1-5,7,10H,6,8-9H2,(H,23,24,26)
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n/an/a 185n/an/an/an/a7.4n/a



Shionogi & Co., Ltd.

US Patent


Assay Description
Two days prior to performing this assay, cells are seeded on poly-D-lysine-coated 96-well clear-bottom black plates (commercially available from Bect...


US Patent US8921373 (2014)


BindingDB Entry DOI: 10.7270/Q28051BW
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM141514
PNG
(US8921373, 2 | US8921373, 7 | US9365563, 201 | US9...)
Show SMILES FC(F)(F)c1ccc(NC(=O)N2CCC(=CC2)c2ncccc2Cl)nc1 |c:14|
Show InChI InChI=1S/C17H14ClF3N4O/c18-13-2-1-7-22-15(13)11-5-8-25(9-6-11)16(26)24-14-4-3-12(10-23-14)17(19,20)21/h1-5,7,10H,6,8-9H2,(H,23,24,26)
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n/an/a 185n/an/an/an/a7.4n/a



Shionogi & Co., Ltd.

US Patent


Assay Description
Two days prior to performing this assay, cells are seeded on poly-D-lysine-coated 96-well clear-bottom black plates (commercially available from Bect...


US Patent US8921373 (2014)


BindingDB Entry DOI: 10.7270/Q28051BW
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM141520
PNG
(US8921373, 6 | US9365563, 206 | US9878991, Compoun...)
Show SMILES Fc1ccc2nc(NC(=O)N3CCC(F)(CC3)c3ncccc3Cl)sc2c1
Show InChI InChI=1S/C18H15ClF2N4OS/c19-12-2-1-7-22-15(12)18(21)5-8-25(9-6-18)17(26)24-16-23-13-4-3-11(20)10-14(13)27-16/h1-4,7,10H,5-6,8-9H2,(H,23,24,26)
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n/an/a 508n/an/an/an/a7.4n/a



Shionogi & Co., Ltd.

US Patent


Assay Description
Two days prior to performing this assay, cells are seeded in poly-D-lysine-coated 96-well clear-bottom black plates (50,000 cells/well) in growth med...


US Patent US8921373 (2014)


BindingDB Entry DOI: 10.7270/Q28051BW
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM141521
PNG
(US8921373, AEF)
Show SMILES OC[C@@H](O)Cc1cnc(c(Cl)c1)C1(F)CCN(CC1)C(=O)Nc1nc2ccc(cc2s1)C(F)(F)F |r|
Show InChI InChI=1S/C22H21ClF4N4O3S/c23-15-8-12(7-14(33)11-32)10-28-18(15)21(24)3-5-31(6-4-21)20(34)30-19-29-16-2-1-13(22(25,26)27)9-17(16)35-19/h1-2,8-10,14,32-33H,3-7,11H2,(H,29,30,34)/t14-/m0/s1
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n/an/a 614n/an/an/an/a7.4n/a



Shionogi & Co., Ltd.

US Patent


Assay Description
Two days prior to performing this assay, cells are seeded on poly-D-lysine-coated 96-well clear-bottom black plates (commercially available from Bect...


US Patent US8921373 (2014)


BindingDB Entry DOI: 10.7270/Q28051BW
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM141525
PNG
(US8921373, 10)
Show SMILES Fc1ccc2nc(NC(=O)N3CCC(=CC3)c3ncccc3Cl)sc2c1 |c:13|
Show InChI InChI=1S/C18H14ClFN4OS/c19-13-2-1-7-21-16(13)11-5-8-24(9-6-11)18(25)23-17-22-14-4-3-12(20)10-15(14)26-17/h1-5,7,10H,6,8-9H2,(H,22,23,25)
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n/an/a 943n/an/an/an/a7.4n/a



Shionogi & Co., Ltd.

US Patent


Assay Description
Two days prior to performing this assay, cells are seeded on poly-D-lysine-coated 96-well clear-bottom black plates (commercially available from Bect...


US Patent US8921373 (2014)


BindingDB Entry DOI: 10.7270/Q28051BW
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM141520
PNG
(US8921373, 6 | US9365563, 206 | US9878991, Compoun...)
Show SMILES Fc1ccc2nc(NC(=O)N3CCC(F)(CC3)c3ncccc3Cl)sc2c1
Show InChI InChI=1S/C18H15ClF2N4OS/c19-12-2-1-7-22-15(12)18(21)5-8-25(9-6-18)17(26)24-16-23-13-4-3-11(20)10-14(13)27-16/h1-4,7,10H,5-6,8-9H2,(H,23,24,26)
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n/an/a 1.46E+3n/an/an/an/a7.4n/a



Shionogi & Co., Ltd.

US Patent


Assay Description
Two days prior to performing this assay, cells are seeded on poly-D-lysine-coated 96-well clear-bottom black plates (commercially available from Bect...


US Patent US8921373 (2014)


BindingDB Entry DOI: 10.7270/Q28051BW
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%