BDBM141531 US8921373, AAC

SMILES: OCC(O)Cc1cnc(C2=CCN(CC2)C(=O)Nc2ccc(c(Cl)c2)C(F)(F)F)c(Cl)c1

InChI Key: InChIKey=XRTGOKOICCLLQT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 141531   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM141531 (US8921373, AAC) Show SMILES OCC(O)Cc1cnc(C2=CCN(CC2)C(=O)Nc2ccc(c(Cl)c2)C(F)(F)F)c(Cl)c1 |t:9| Show InChI InChI=1S/C21H20Cl2F3N3O3/c22-17-9-14(1-2-16(17)21(24,25)26)28-20(32)29-5-3-13(4-6-29)19-18(23)8-12(10-27-19)7-15(31)11-30/h1-3,8-10,15,30-31H,4-7,11H2,(H,28,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	7.4	n/a
Shionogi & Co., Ltd. US Patent					Assay Description Two days prior to performing this assay, cells are seeded on poly-D-lysine-coated 96-well clear-bottom black plates (commercially available from Bect...				US Patent US8921373 (2014) BindingDB Entry DOI: 10.7270/Q28051BW
					More data for this Ligand-Target Pair