Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mitogen-activated protein kinase 13 (Homo sapiens (Human)) | BDBM192498 (US9187470, 89) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 27.5 | n/a | n/a | n/a | n/a | n/a | 25 |
Washington University US Patent | Assay Description The MAPK13 blocking activity of test compounds was determined using an immobilized metal affinity polarization (IMAP) assay containing activated MAPK... | US Patent US9187470 (2015) BindingDB Entry DOI: 10.7270/Q2N878M9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 13 (Homo sapiens (Human)) | BDBM50249406 (1-(3-tert-butyl-1-methyl-1H-pyrazol-5-yl)-3-(4-(py...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PDB US Patent | n/a | n/a | 82.7 | n/a | n/a | n/a | n/a | n/a | 25 |
Washington University US Patent | Assay Description The MAPK13 blocking activity of test compounds was determined using an immobilized metal affinity polarization (IMAP) assay containing activated MAPK... | US Patent US9187470 (2015) BindingDB Entry DOI: 10.7270/Q2N878M9 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Mitogen-activated protein kinase 13 (Homo sapiens (Human)) | BDBM192497 (US9187470, 62) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 281 | n/a | n/a | n/a | n/a | n/a | 25 |
Washington University US Patent | Assay Description The MAPK13 blocking activity of test compounds was determined using an immobilized metal affinity polarization (IMAP) assay containing activated MAPK... | US Patent US9187470 (2015) BindingDB Entry DOI: 10.7270/Q2N878M9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 13 (Homo sapiens (Human)) | BDBM50249406 (1-(3-tert-butyl-1-methyl-1H-pyrazol-5-yl)-3-(4-(py...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PDB US Patent | n/a | n/a | 620 | n/a | n/a | n/a | n/a | n/a | 25 |
Washington University US Patent | Assay Description The MAPK13 blocking activity of test compounds was determined using an immobilized metal affinity polarization (IMAP) assay containing activated MAPK... | US Patent US9187470 (2015) BindingDB Entry DOI: 10.7270/Q2N878M9 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Mitogen-activated protein kinase 13 (Homo sapiens (Human)) | BDBM13533 (1-[2-(4-methylphenyl)-5-tert-butyl-pyrazol-3-yl]-3...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | US Patent | n/a | n/a | 1.97E+3 | n/a | n/a | n/a | n/a | n/a | 25 |
Washington University US Patent | Assay Description The MAPK13 blocking activity of test compounds was determined using an immobilized metal affinity polarization (IMAP) assay containing activated MAPK... | US Patent US9187470 (2015) BindingDB Entry DOI: 10.7270/Q2N878M9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 13 (Homo sapiens (Human)) | BDBM50303597 ((S)-2-(2-amino-3-phenylpropylamino)-3-methyl-5-(na...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem | US Patent | n/a | n/a | 7.74E+3 | n/a | n/a | n/a | n/a | n/a | 25 |
Washington University US Patent | Assay Description The MAPK13 blocking activity of test compounds was determined using an immobilized metal affinity polarization (IMAP) assay containing activated MAPK... | US Patent US9187470 (2015) BindingDB Entry DOI: 10.7270/Q2N878M9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 13 (Homo sapiens (Human)) | BDBM192500 (US9187470, 115) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 8.65E+3 | n/a | n/a | n/a | n/a | n/a | 25 |
Washington University US Patent | Assay Description The MAPK13 blocking activity of test compounds was determined using an immobilized metal affinity polarization (IMAP) assay containing activated MAPK... | US Patent US9187470 (2015) BindingDB Entry DOI: 10.7270/Q2N878M9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 13 (Homo sapiens (Human)) | BDBM192499 (US9187470, 117) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB US Patent | n/a | n/a | 1.02E+4 | n/a | n/a | n/a | n/a | n/a | 25 |
Washington University US Patent | Assay Description The MAPK13 blocking activity of test compounds was determined using an immobilized metal affinity polarization (IMAP) assay containing activated MAPK... | US Patent US9187470 (2015) BindingDB Entry DOI: 10.7270/Q2N878M9 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Mitogen-activated protein kinase 13 (Homo sapiens (Human)) | BDBM192502 (US9187470, 124) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB US Patent | n/a | n/a | 1.49E+4 | n/a | n/a | n/a | n/a | n/a | 25 |
Washington University US Patent | Assay Description The MAPK13 blocking activity of test compounds was determined using an immobilized metal affinity polarization (IMAP) assay containing activated MAPK... | US Patent US9187470 (2015) BindingDB Entry DOI: 10.7270/Q2N878M9 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Mitogen-activated protein kinase 13 (Homo sapiens (Human)) | BDBM192499 (US9187470, 117) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB US Patent | n/a | n/a | 1.58E+4 | n/a | n/a | n/a | n/a | n/a | 25 |
Washington University US Patent | Assay Description The MAPK13 blocking activity of test compounds was determined using an immobilized metal affinity polarization (IMAP) assay containing activated MAPK... | US Patent US9187470 (2015) BindingDB Entry DOI: 10.7270/Q2N878M9 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Mitogen-activated protein kinase 13 (Homo sapiens (Human)) | BDBM192502 (US9187470, 124) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB US Patent | n/a | n/a | 9.87E+4 | n/a | n/a | n/a | n/a | n/a | 25 |
Washington University US Patent | Assay Description The MAPK13 blocking activity of test compounds was determined using an immobilized metal affinity polarization (IMAP) assay containing activated MAPK... | US Patent US9187470 (2015) BindingDB Entry DOI: 10.7270/Q2N878M9 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Mitogen-activated protein kinase 13 (Homo sapiens (Human)) | BDBM192501 (US10865384, Compound SB203580 | US9187470, 104 (SB...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 8.76E+7 | n/a | n/a | n/a | n/a | n/a | 25 |
Washington University US Patent | Assay Description The MAPK13 blocking activity of test compounds was determined using an immobilized metal affinity polarization (IMAP) assay containing activated MAPK... | US Patent US9187470 (2015) BindingDB Entry DOI: 10.7270/Q2N878M9 | |||||||||||
More data for this Ligand-Target Pair |