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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| N-lysine methyltransferase SMYD2 (Homo sapiens (Human)) | BDBM50095537 (CHEMBL3590526 | US9598381, 1a (S enantiomer)) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet  | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | PDB US Patent | n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Binding affinity of compounds having formula (I) to SMYD2 is indicia of their inhibition of the activity of this protein lysine methyltransferase. To... | US Patent US9598381 (2017) BindingDB Entry DOI: 10.7270/Q2VQ34QT | |||||||||||
| More data for this Ligand-Target Pair |  3D Structure (crystal) | ||||||||||||
| N-lysine methyltransferase SMYD2 (Homo sapiens (Human)) | BDBM50095536 (CHEMBL3590527 | US9598381, 1 (racemate)) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 65 | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Binding affinity of compounds having formula (I) to SMYD2 is indicia of their inhibition of the activity of this protein lysine methyltransferase. To... | US Patent US9598381 (2017) BindingDB Entry DOI: 10.7270/Q2VQ34QT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| N-lysine methyltransferase SMYD2 (Homo sapiens (Human)) | BDBM50095635 (CHEMBL3590518 | US9598381, 2) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 138 | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Binding affinity of compounds having formula (I) to SMYD2 is indicia of their inhibition of the activity of this protein lysine methyltransferase. To... | US Patent US9598381 (2017) BindingDB Entry DOI: 10.7270/Q2VQ34QT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| N-lysine methyltransferase SMYD2 (Homo sapiens (Human)) | BDBM50095635 (CHEMBL3590518 | US9598381, 2) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.03E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Binding affinity of compounds having formula (I) to SMYD2 is indicia of their inhibition of the activity of this protein lysine methyltransferase. To... | US Patent US9598381 (2017) BindingDB Entry DOI: 10.7270/Q2VQ34QT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| N-lysine methyltransferase SMYD2 (Homo sapiens (Human)) | BDBM301823 ( N-cyclohexyl-3-((2,3-dichlorophenethyl)amino)-N-(...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.44E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Binding affinity of compounds having formula (I) to SMYD2 is indicia of their inhibition of the activity of this protein lysine methyltransferase. To... | US Patent US9598381 (2017) BindingDB Entry DOI: 10.7270/Q2VQ34QT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| N-lysine methyltransferase SMYD2 (Homo sapiens (Human)) | BDBM50095633 (CHEMBL3590520 | US9598381, 3) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3.74E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Binding affinity of compounds having formula (I) to SMYD2 is indicia of their inhibition of the activity of this protein lysine methyltransferase. To... | US Patent US9598381 (2017) BindingDB Entry DOI: 10.7270/Q2VQ34QT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| N-lysine methyltransferase SMYD2 (Homo sapiens (Human)) | BDBM301822 (N-cyclobutyl-3-((3,4-dichlorophenethyl)amino)-N-(2...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.79E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Binding affinity of compounds having formula (I) to SMYD2 is indicia of their inhibition of the activity of this protein lysine methyltransferase. To... | US Patent US9598381 (2017) BindingDB Entry DOI: 10.7270/Q2VQ34QT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| N-lysine methyltransferase SMYD2 (Homo sapiens (Human)) | BDBM50095615 (CHEMBL3590524 | US9598381, 13) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 7.42E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Binding affinity of compounds having formula (I) to SMYD2 is indicia of their inhibition of the activity of this protein lysine methyltransferase. To... | US Patent US9598381 (2017) BindingDB Entry DOI: 10.7270/Q2VQ34QT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| N-lysine methyltransferase SMYD2 (Homo sapiens (Human)) | BDBM301815 ( N-cyclohexyl-3-((3,4-dichlorophenethyl)amino)-N-(...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 9.83E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Binding affinity of compounds having formula (I) to SMYD2 is indicia of their inhibition of the activity of this protein lysine methyltransferase. To... | US Patent US9598381 (2017) BindingDB Entry DOI: 10.7270/Q2VQ34QT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| N-lysine methyltransferase SMYD2 (Homo sapiens (Human)) | BDBM301797 (N-cyclopentyl-3-((3,4-dichlorophenethyl)amino)-N-(...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Binding affinity of compounds having formula (I) to SMYD2 is indicia of their inhibition of the activity of this protein lysine methyltransferase. To... | US Patent US9598381 (2017) BindingDB Entry DOI: 10.7270/Q2VQ34QT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| N-lysine methyltransferase SMYD2 (Homo sapiens (Human)) | BDBM50095612 (CHEMBL3590525 | US9598381, 5) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.12E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Binding affinity of compounds having formula (I) to SMYD2 is indicia of their inhibition of the activity of this protein lysine methyltransferase. To... | US Patent US9598381 (2017) BindingDB Entry DOI: 10.7270/Q2VQ34QT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| N-lysine methyltransferase SMYD2 (Homo sapiens (Human)) | BDBM50095625 (CHEMBL3590523 | US9598381, 6) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.21E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Binding affinity of compounds having formula (I) to SMYD2 is indicia of their inhibition of the activity of this protein lysine methyltransferase. To... | US Patent US9598381 (2017) BindingDB Entry DOI: 10.7270/Q2VQ34QT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| N-lysine methyltransferase SMYD2 (Homo sapiens (Human)) | BDBM301805 (N-(2-((4-cyanobenzyl)amino)ethyl)-N-cyclohexyl-((3...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Binding affinity of compounds having formula (I) to SMYD2 is indicia of their inhibition of the activity of this protein lysine methyltransferase. To... | US Patent US9598381 (2017) BindingDB Entry DOI: 10.7270/Q2VQ34QT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| N-lysine methyltransferase SMYD2 (Homo sapiens (Human)) | BDBM301811 (N-cyclohexyl-3-((3,4-dichlorophenethyl)amino)-N-(2...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.28E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Binding affinity of compounds having formula (I) to SMYD2 is indicia of their inhibition of the activity of this protein lysine methyltransferase. To... | US Patent US9598381 (2017) BindingDB Entry DOI: 10.7270/Q2VQ34QT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| N-lysine methyltransferase SMYD2 (Homo sapiens (Human)) | BDBM50095634 (CHEMBL3590519 | US9598381, 11) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Binding affinity of compounds having formula (I) to SMYD2 is indicia of their inhibition of the activity of this protein lysine methyltransferase. To... | US Patent US9598381 (2017) BindingDB Entry DOI: 10.7270/Q2VQ34QT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| N-lysine methyltransferase SMYD2 (Homo sapiens (Human)) | BDBM301812 ((S)-N-cyclohexyl-3-(phenethylamino)-N-(2-(2-((pyri...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Binding affinity of compounds having formula (I) to SMYD2 is indicia of their inhibition of the activity of this protein lysine methyltransferase. To... | US Patent US9598381 (2017) BindingDB Entry DOI: 10.7270/Q2VQ34QT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| N-lysine methyltransferase SMYD2 (Homo sapiens (Human)) | BDBM301813 (N-cyclohexyl-N-(2-((2-(5-hydroxy-3-oxo-3,4-dihydro...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Binding affinity of compounds having formula (I) to SMYD2 is indicia of their inhibition of the activity of this protein lysine methyltransferase. To... | US Patent US9598381 (2017) BindingDB Entry DOI: 10.7270/Q2VQ34QT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| N-lysine methyltransferase SMYD2 (Homo sapiens (Human)) | BDBM50095632 (CHEMBL3590521 | US9598381, 14) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. US Patent | Assay Description Binding affinity of compounds having formula (I) to SMYD2 is indicia of their inhibition of the activity of this protein lysine methyltransferase. To... | US Patent US9598381 (2017) BindingDB Entry DOI: 10.7270/Q2VQ34QT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
