Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'N-lysine methyltransferase SMYD2' and Ligand = 'BDBM301823'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
N-lysine methyltransferase SMYD2 (Homo sapiens (Human))	BDBM301823 ( N-cyclohexyl-3-((2,3-dichlorophenethyl)amino)-N-(...) Show SMILES Cc1cn2ccccc2c1CCNCCN(C1CCCCC1)C(=O)CCNCCc1cccc(Cl)c1Cl Show InChI InChI=1S/C30H40Cl2N4O/c1-23-22-35-20-6-5-12-28(35)26(23)14-17-34-19-21-36(25-9-3-2-4-10-25)29(37)15-18-33-16-13-24-8-7-11-27(31)30(24)32/h5-8,11-12,20,22,25,33-34H,2-4,9-10,13-19,21H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.44E+3	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description Binding affinity of compounds having formula (I) to SMYD2 is indicia of their inhibition of the activity of this protein lysine methyltransferase. To...				US Patent US9598381 (2017) BindingDB Entry DOI: 10.7270/Q2VQ34QT
					More data for this Ligand-Target Pair