Affinity Data by Patent

Patent code US9212145

Found 3 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM196651 (US9212145, I-1) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a
Kala Pharmaceuticals, Inc. US Patent					Assay Description A competition binding assay (DiscoveRx KINOMEscan) was used to measure the ability of the compound to compete for binding of an immobilized adenosine...				US Patent US9212145 (2015) BindingDB Entry DOI: 10.7270/Q2F76BBZ
Kala Pharmaceuticals, Inc. US Patent					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM196653 (US9212145, II-1) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	5.10E+5	n/a	n/a	n/a	n/a	n/a
Kala Pharmaceuticals, Inc. US Patent					Assay Description A competition binding assay (DiscoveRx KINOMEscan) was used to measure the ability of the compound to compete for binding of an immobilized adenosine...				US Patent US9212145 (2015) BindingDB Entry DOI: 10.7270/Q2F76BBZ
Kala Pharmaceuticals, Inc. US Patent					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM196652 (US10329280, Compound I-2 \| US9212145, I-2) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a
Kala Pharmaceuticals, Inc. US Patent					Assay Description A competition binding assay (DiscoveRx KINOMEscan) was used to measure the ability of the compound to compete for binding of an immobilized adenosine...				US Patent US9212145 (2015) BindingDB Entry DOI: 10.7270/Q2F76BBZ
Kala Pharmaceuticals, Inc. US Patent					More data for this Ligand-Target Pair

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* indicates data uncertainty>20%