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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Tyrosine-protein kinase JAK1 (Homo sapiens (Human)) | BDBM128101 (US10206907, Compound 330 | US8796457, 1 | US950575...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet  | Purchase MCE PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 6.60 | n/a | n/a | n/a | n/a | n/a | 25 |
Galapagos NV US Patent | Assay Description Recombinant human JAK1 (catalytic domain, amino acids 866-1154; catalog number PV4774) was purchased from Invitrogen. 1 ng of JAK1 was incubated with... | US Patent US8796457 (2014) BindingDB Entry DOI: 10.7270/Q2XK8D70 | |||||||||||
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