Affinity Data by Patent

Patent code US8623892

Found 13 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM111999 (US8623892, 1) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Viamet Pharmaceuticals, Inc. US Patent					Assay Description In the design of clinically safe and effective metalloenzyme inhibitors, use of the most appropriate metal-binding group for the particular target an...				US Patent US8623892 (2014) BindingDB Entry DOI: 10.7270/Q2PG1QCN
Viamet Pharmaceuticals, Inc. US Patent					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM112001 (US8623892, 3) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Viamet Pharmaceuticals, Inc. US Patent					Assay Description In the design of clinically safe and effective metalloenzyme inhibitors, use of the most appropriate metal-binding group for the particular target an...				US Patent US8623892 (2014) BindingDB Entry DOI: 10.7270/Q2PG1QCN
Viamet Pharmaceuticals, Inc. US Patent					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM112002 (US8623892, 4) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	510	n/a	n/a	n/a	n/a	n/a	n/a
Viamet Pharmaceuticals, Inc. US Patent					Assay Description In the design of clinically safe and effective metalloenzyme inhibitors, use of the most appropriate metal-binding group for the particular target an...				US Patent US8623892 (2014) BindingDB Entry DOI: 10.7270/Q2PG1QCN
Viamet Pharmaceuticals, Inc. US Patent					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM112000 (US8623892, 2) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	960	n/a	n/a	n/a	n/a	n/a	n/a
Viamet Pharmaceuticals, Inc. US Patent					Assay Description In the design of clinically safe and effective metalloenzyme inhibitors, use of the most appropriate metal-binding group for the particular target an...				US Patent US8623892 (2014) BindingDB Entry DOI: 10.7270/Q2PG1QCN
Viamet Pharmaceuticals, Inc. US Patent					More data for this Ligand-Target Pair
Cytochrome P450 2C19 (Homo sapiens (Human))	BDBM112000 (US8623892, 2) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Viamet Pharmaceuticals, Inc. US Patent					Assay Description In the design of clinically safe and effective metalloenzyme inhibitors, use of the most appropriate metal-binding group for the particular target an...				US Patent US8623892 (2014) BindingDB Entry DOI: 10.7270/Q2PG1QCN
Viamet Pharmaceuticals, Inc. US Patent					More data for this Ligand-Target Pair
Cytochrome P450 2C9 (Homo sapiens (Human))	BDBM112001 (US8623892, 3) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Viamet Pharmaceuticals, Inc. US Patent					Assay Description In the design of clinically safe and effective metalloenzyme inhibitors, use of the most appropriate metal-binding group for the particular target an...				US Patent US8623892 (2014) BindingDB Entry DOI: 10.7270/Q2PG1QCN
Viamet Pharmaceuticals, Inc. US Patent					More data for this Ligand-Target Pair
Cytochrome P450 2C19 (Homo sapiens (Human))	BDBM112001 (US8623892, 3) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Viamet Pharmaceuticals, Inc. US Patent					Assay Description In the design of clinically safe and effective metalloenzyme inhibitors, use of the most appropriate metal-binding group for the particular target an...				US Patent US8623892 (2014) BindingDB Entry DOI: 10.7270/Q2PG1QCN
Viamet Pharmaceuticals, Inc. US Patent					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM112001 (US8623892, 3) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Viamet Pharmaceuticals, Inc. US Patent					Assay Description In the design of clinically safe and effective metalloenzyme inhibitors, use of the most appropriate metal-binding group for the particular target an...				US Patent US8623892 (2014) BindingDB Entry DOI: 10.7270/Q2PG1QCN
Viamet Pharmaceuticals, Inc. US Patent					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM112000 (US8623892, 2) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Viamet Pharmaceuticals, Inc. US Patent					Assay Description In the design of clinically safe and effective metalloenzyme inhibitors, use of the most appropriate metal-binding group for the particular target an...				US Patent US8623892 (2014) BindingDB Entry DOI: 10.7270/Q2PG1QCN
Viamet Pharmaceuticals, Inc. US Patent					More data for this Ligand-Target Pair
Cytochrome P450 2C9 (Homo sapiens (Human))	BDBM112000 (US8623892, 2) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Viamet Pharmaceuticals, Inc. US Patent					Assay Description In the design of clinically safe and effective metalloenzyme inhibitors, use of the most appropriate metal-binding group for the particular target an...				US Patent US8623892 (2014) BindingDB Entry DOI: 10.7270/Q2PG1QCN
Viamet Pharmaceuticals, Inc. US Patent					More data for this Ligand-Target Pair
Cytochrome P450 2C19 (Homo sapiens (Human))	BDBM111999 (US8623892, 1) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Viamet Pharmaceuticals, Inc. US Patent					Assay Description In the design of clinically safe and effective metalloenzyme inhibitors, use of the most appropriate metal-binding group for the particular target an...				US Patent US8623892 (2014) BindingDB Entry DOI: 10.7270/Q2PG1QCN
Viamet Pharmaceuticals, Inc. US Patent					More data for this Ligand-Target Pair
Cytochrome P450 2C9 (Homo sapiens (Human))	BDBM111999 (US8623892, 1) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Viamet Pharmaceuticals, Inc. US Patent					Assay Description In the design of clinically safe and effective metalloenzyme inhibitors, use of the most appropriate metal-binding group for the particular target an...				US Patent US8623892 (2014) BindingDB Entry DOI: 10.7270/Q2PG1QCN
Viamet Pharmaceuticals, Inc. US Patent					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM111999 (US8623892, 1) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Viamet Pharmaceuticals, Inc. US Patent					Assay Description In the design of clinically safe and effective metalloenzyme inhibitors, use of the most appropriate metal-binding group for the particular target an...				US Patent US8623892 (2014) BindingDB Entry DOI: 10.7270/Q2PG1QCN
Viamet Pharmaceuticals, Inc. US Patent					More data for this Ligand-Target Pair

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* indicates data uncertainty>20%