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Patent code US8691856

Compile Data Set for Download or QSAR
Found 2 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glucagon receptor


(Homo sapiens (Human))		BDBM119833
PNG
(US8691856, 13)
Show SMILES Cc1cc(OC(CCC(F)(F)F)c2ccc(cc2)C(=O)NCc2nnn[nH]2)cc(C)c1-c1ccc(cc1)C(C)(C)C
Show InChI InChI=1S/C31H34F3N5O2/c1-19-16-25(17-20(2)28(19)22-10-12-24(13-11-22)30(3,4)5)41-26(14-15-31(32,33)34)21-6-8-23(9-7-21)29(40)35-18-27-36-38-39-37-27/h6-13,16-17,26H,14-15,18H2,1-5H3,(H,35,40)(H,36,37,38,39)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
 63.4n/an/an/an/an/an/a7.4n/a



Eli Lilly and Company

US Patent


Assay Description
The binding assays are carried out using a Scintillation Proximity Assay (Amersham) with WGA beads previously blocked with 1% fatty acid free BSA (IC...

US Patent US8691856 (2014)


BindingDB Entry DOI: 10.7270/Q2BK1B03
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))		BDBM119834
PNG
(US8691856, 27)
Show SMILES Cc1cc(OC(CCC(C)(C)C)c2ccc(cc2)C(=O)Nc2nnn[nH]2)cc(C)c1-c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C30H32F3N5O2/c1-18-16-24(17-19(2)26(18)21-10-12-23(13-11-21)30(31,32)33)40-25(14-15-29(3,4)5)20-6-8-22(9-7-20)27(39)34-28-35-37-38-36-28/h6-13,16-17,25H,14-15H2,1-5H3,(H2,34,35,36,37,38,39)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
 93.3n/an/an/an/an/an/a7.4n/a



Eli Lilly and Company

US Patent


Assay Description
The binding assays are carried out using a Scintillation Proximity Assay (Amersham) with WGA beads previously blocked with 1% fatty acid free BSA (IC...

US Patent US8691856 (2014)


BindingDB Entry DOI: 10.7270/Q2BK1B03
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%