BindingDB logo
myBDB logout

Patent code US9079906

Compile Data Set for Download or QSAR
Found 27 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Proteinase-activated receptor 1


(Homo sapiens (Human))
BDBM169633
PNG
(US9079906, 117)
Show SMILES CCC(CC)Oc1cc(C)c2nn(CC(=O)c3cc(OCCO)c(OC)c(c3)C(C)(C)C)c(=N)n2n1
Show InChI InChI=1S/C26H37N5O5/c1-8-18(9-2)36-22-12-16(3)24-29-30(25(27)31(24)28-22)15-20(33)17-13-19(26(4,5)6)23(34-7)21(14-17)35-11-10-32/h12-14,18,27,32H,8-11,15H2,1-7H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 98n/an/an/an/a7.525



Sanofi

US Patent


Assay Description
The synthesized substances were examined in a PAR1 binding test. This tested whether the substances can inhibit the binding of a radioactively labele...


US Patent US9079906 (2015)


BindingDB Entry DOI: 10.7270/Q2251GZP
More data for this
Ligand-Target Pair
Proteinase-activated receptor 1


(Homo sapiens (Human))
BDBM169631
PNG
(US9079906, 89)
Show SMILES CCC(CC)Oc1cc(C)c2nn(CC(=O)c3cc(OCCO)cc(c3)C(C)(C)C)c(=N)n2n1
Show InChI InChI=1S/C25H35N5O4/c1-7-19(8-2)34-22-11-16(3)23-28-29(24(26)30(23)27-22)15-21(32)17-12-18(25(4,5)6)14-20(13-17)33-10-9-31/h11-14,19,26,31H,7-10,15H2,1-6H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 107n/an/an/an/a7.525



Sanofi

US Patent


Assay Description
The synthesized substances were examined in a PAR1 binding test. This tested whether the substances can inhibit the binding of a radioactively labele...


US Patent US9079906 (2015)


BindingDB Entry DOI: 10.7270/Q2251GZP
More data for this
Ligand-Target Pair
Proteinase-activated receptor 1


(Homo sapiens (Human))
BDBM169650
PNG
(US9079906, 239)
Show SMILES CCNC(=O)c1nn2c(nn(CC(=O)c3cc(OCCCO)c(OC)c(c3)C(C)(C)C)\c2=N/C)c(C)c1C
Show InChI InChI=1S/C27H38N6O5/c1-9-29-25(36)22-16(2)17(3)24-31-32(26(28-7)33(24)30-22)15-20(35)18-13-19(27(4,5)6)23(37-8)21(14-18)38-12-10-11-34/h13-14,34H,9-12,15H2,1-8H3,(H,29,36)/b28-26+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 113n/an/an/an/a7.525



Sanofi

US Patent


Assay Description
The synthesized substances were examined in a PAR1 binding test. This tested whether the substances can inhibit the binding of a radioactively labele...


US Patent US9079906 (2015)


BindingDB Entry DOI: 10.7270/Q2251GZP
More data for this
Ligand-Target Pair
Proteinase-activated receptor 1


(Homo sapiens (Human))
BDBM169641
PNG
(US9079906, 186)
Show SMILES CCN(CC)c1nn2c(nn(CC(=O)c3cc(OCCCO)c(OC)c(c3)C(C)(C)C)c2=N)c(C)c1C
Show InChI InChI=1S/C27H40N6O4/c1-9-31(10-2)24-17(3)18(4)25-29-32(26(28)33(25)30-24)16-21(35)19-14-20(27(5,6)7)23(36-8)22(15-19)37-13-11-12-34/h14-15,28,34H,9-13,16H2,1-8H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 119n/an/an/an/a7.525



Sanofi

US Patent


Assay Description
The synthesized substances were examined in a PAR1 binding test. This tested whether the substances can inhibit the binding of a radioactively labele...


US Patent US9079906 (2015)


BindingDB Entry DOI: 10.7270/Q2251GZP
More data for this
Ligand-Target Pair
Proteinase-activated receptor 1


(Homo sapiens (Human))
BDBM169640
PNG
(US9079906, 178)
Show SMILES CCOc1nn2c(nn(CC(=O)c3cc(OCCCCO)c(OC)c(c3)C(C)(C)C)c2=N)c(C)c1C
Show InChI InChI=1S/C26H37N5O5/c1-8-35-24-17(3)16(2)23-28-30(25(27)31(23)29-24)15-20(33)18-13-19(26(4,5)6)22(34-7)21(14-18)36-12-10-9-11-32/h13-14,27,32H,8-12,15H2,1-7H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 126n/an/an/an/a7.525



Sanofi

US Patent


Assay Description
The synthesized substances were examined in a PAR1 binding test. This tested whether the substances can inhibit the binding of a radioactively labele...


US Patent US9079906 (2015)


BindingDB Entry DOI: 10.7270/Q2251GZP
More data for this
Ligand-Target Pair
Proteinase-activated receptor 1


(Homo sapiens (Human))
BDBM169642
PNG
(US9079906, 197)
Show SMILES CCOc1nn2c(nn(CC(=O)c3cc(OCCCO)c(OC)c(c3)C(C)(C)C)c2=N)c(CC)c1CC
Show InChI InChI=1S/C27H39N5O5/c1-8-18-19(9-2)25(36-10-3)30-32-24(18)29-31(26(32)28)16-21(34)17-14-20(27(4,5)6)23(35-7)22(15-17)37-13-11-12-33/h14-15,28,33H,8-13,16H2,1-7H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 149n/an/an/an/a7.525



Sanofi

US Patent


Assay Description
The synthesized substances were examined in a PAR1 binding test. This tested whether the substances can inhibit the binding of a radioactively labele...


US Patent US9079906 (2015)


BindingDB Entry DOI: 10.7270/Q2251GZP
More data for this
Ligand-Target Pair
Proteinase-activated receptor 1


(Homo sapiens (Human))
BDBM169646
PNG
(US9079906, 221)
Show SMILES CCOc1nn2c(nn(CC(=O)c3cc(OCCO)cc(c3)C(C)(C)C)c2=N)c(CC)c1C
Show InChI InChI=1S/C24H33N5O4/c1-7-19-15(3)22(32-8-2)27-29-21(19)26-28(23(29)25)14-20(31)16-11-17(24(4,5)6)13-18(12-16)33-10-9-30/h11-13,25,30H,7-10,14H2,1-6H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 155n/an/an/an/a7.525



Sanofi

US Patent


Assay Description
The synthesized substances were examined in a PAR1 binding test. This tested whether the substances can inhibit the binding of a radioactively labele...


US Patent US9079906 (2015)


BindingDB Entry DOI: 10.7270/Q2251GZP
More data for this
Ligand-Target Pair
Proteinase-activated receptor 1


(Homo sapiens (Human))
BDBM169644
PNG
(US9079906, 207)
Show SMILES CCNC(=O)c1nn2c(nn(CC(=O)c3cc(OCCO)c(OC)c(c3)C(C)(C)C)\c2=N/C)c(C)c1C
Show InChI InChI=1S/C26H36N6O5/c1-9-28-24(35)21-15(2)16(3)23-30-31(25(27-7)32(23)29-21)14-19(34)17-12-18(26(4,5)6)22(36-8)20(13-17)37-11-10-33/h12-13,33H,9-11,14H2,1-8H3,(H,28,35)/b27-25+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 174n/an/an/an/a7.525



Sanofi

US Patent


Assay Description
The synthesized substances were examined in a PAR1 binding test. This tested whether the substances can inhibit the binding of a radioactively labele...


US Patent US9079906 (2015)


BindingDB Entry DOI: 10.7270/Q2251GZP
More data for this
Ligand-Target Pair
Proteinase-activated receptor 1


(Homo sapiens (Human))
BDBM169639
PNG
(US9079906, 174)
Show SMILES CCOc1cc(CC)c2nn(CC(=O)c3cc(OCCCO)c(OC)c(c3)C(C)(C)C)c(=N)n2n1
Show InChI InChI=1S/C25H35N5O5/c1-7-16-14-21(34-8-2)27-30-23(16)28-29(24(30)26)15-19(32)17-12-18(25(3,4)5)22(33-6)20(13-17)35-11-9-10-31/h12-14,26,31H,7-11,15H2,1-6H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 183n/an/an/an/a7.525



Sanofi

US Patent


Assay Description
The synthesized substances were examined in a PAR1 binding test. This tested whether the substances can inhibit the binding of a radioactively labele...


US Patent US9079906 (2015)


BindingDB Entry DOI: 10.7270/Q2251GZP
More data for this
Ligand-Target Pair
Proteinase-activated receptor 1


(Homo sapiens (Human))
BDBM169643
PNG
(US9079906, 199)
Show SMILES COc1c(OCCCCO)cc(cc1C(C)(C)C)C(=O)Cn1nc2c(C)cc(OCC3CC3)nn2c1=N
Show InChI InChI=1S/C27H37N5O5/c1-17-12-23(37-16-18-8-9-18)29-32-25(17)30-31(26(32)28)15-21(34)19-13-20(27(2,3)4)24(35-5)22(14-19)36-11-7-6-10-33/h12-14,18,28,33H,6-11,15-16H2,1-5H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 206n/an/an/an/a7.525



Sanofi

US Patent


Assay Description
The synthesized substances were examined in a PAR1 binding test. This tested whether the substances can inhibit the binding of a radioactively labele...


US Patent US9079906 (2015)


BindingDB Entry DOI: 10.7270/Q2251GZP
More data for this
Ligand-Target Pair
Proteinase-activated receptor 1


(Homo sapiens (Human))
BDBM169645
PNG
(US9079906, 215)
Show SMILES CC(C)Oc1nn2c(nn(CC(=O)c3cc(OCCO)cc(c3)C(C)(C)C)c2=N)c(C)c1C
Show InChI InChI=1S/C24H33N5O4/c1-14(2)33-22-16(4)15(3)21-26-28(23(25)29(21)27-22)13-20(31)17-10-18(24(5,6)7)12-19(11-17)32-9-8-30/h10-12,14,25,30H,8-9,13H2,1-7H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 219n/an/an/an/a7.525



Sanofi

US Patent


Assay Description
The synthesized substances were examined in a PAR1 binding test. This tested whether the substances can inhibit the binding of a radioactively labele...


US Patent US9079906 (2015)


BindingDB Entry DOI: 10.7270/Q2251GZP
More data for this
Ligand-Target Pair
Proteinase-activated receptor 1


(Homo sapiens (Human))
BDBM169648
PNG
(US9079906, 230)
Show SMILES CCOc1nn2c(nn(CC(=O)c3cc(cc(c3)C(C)(C)OC)C(C)(C)C)c2=N)c(C)c1C
Show InChI InChI=1S/C25H35N5O3/c1-10-33-22-16(3)15(2)21-27-29(23(26)30(21)28-22)14-20(31)17-11-18(24(4,5)6)13-19(12-17)25(7,8)32-9/h11-13,26H,10,14H2,1-9H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 234n/an/an/an/a7.525



Sanofi

US Patent


Assay Description
The synthesized substances were examined in a PAR1 binding test. This tested whether the substances can inhibit the binding of a radioactively labele...


US Patent US9079906 (2015)


BindingDB Entry DOI: 10.7270/Q2251GZP
More data for this
Ligand-Target Pair
Proteinase-activated receptor 1


(Homo sapiens (Human))
BDBM169638
PNG
(US9079906, 168)
Show SMILES CCOc1cc(c2nn(CC(=O)c3cc(OCCCO)c(OC)c(c3)C(C)(C)C)c(=N)n2n1)C(C)(C)O
Show InChI InChI=1S/C26H37N5O6/c1-8-36-21-14-18(26(5,6)34)23-29-30(24(27)31(23)28-21)15-19(33)16-12-17(25(2,3)4)22(35-7)20(13-16)37-11-9-10-32/h12-14,27,32,34H,8-11,15H2,1-7H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 257n/an/an/an/a7.525



Sanofi

US Patent


Assay Description
The synthesized substances were examined in a PAR1 binding test. This tested whether the substances can inhibit the binding of a radioactively labele...


US Patent US9079906 (2015)


BindingDB Entry DOI: 10.7270/Q2251GZP
More data for this
Ligand-Target Pair
Proteinase-activated receptor 1


(Homo sapiens (Human))
BDBM169625
PNG
(US9079906, 14)
Show SMILES CCC(CC)Oc1ccc2nn(CC(=O)c3cc(N4CCOCC4)c(OC)c(c3)C(C)(C)C)c(=N)n2n1
Show InChI InChI=1S/C27H38N6O4/c1-7-19(8-2)37-24-10-9-23-29-32(26(28)33(23)30-24)17-22(34)18-15-20(27(3,4)5)25(35-6)21(16-18)31-11-13-36-14-12-31/h9-10,15-16,19,28H,7-8,11-14,17H2,1-6H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 279n/an/an/an/a7.525



Sanofi

US Patent


Assay Description
The synthesized substances were examined in a PAR1 binding test. This tested whether the substances can inhibit the binding of a radioactively labele...


US Patent US9079906 (2015)


BindingDB Entry DOI: 10.7270/Q2251GZP
More data for this
Ligand-Target Pair
Proteinase-activated receptor 1


(Homo sapiens (Human))
BDBM169637
PNG
(US9079906, 163)
Show SMILES CCOc1nn2c(nn(CC(=O)c3cc(OCCO)cc(c3)C(C)(C)C)\c2=N/C)c(C)c1C
Show InChI InChI=1S/C24H33N5O4/c1-8-32-22-16(3)15(2)21-26-28(23(25-7)29(21)27-22)14-20(31)17-11-18(24(4,5)6)13-19(12-17)33-10-9-30/h11-13,30H,8-10,14H2,1-7H3/b25-23+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 364n/an/an/an/a7.525



Sanofi

US Patent


Assay Description
The synthesized substances were examined in a PAR1 binding test. This tested whether the substances can inhibit the binding of a radioactively labele...


US Patent US9079906 (2015)


BindingDB Entry DOI: 10.7270/Q2251GZP
More data for this
Ligand-Target Pair
Proteinase-activated receptor 1


(Homo sapiens (Human))
BDBM169636
PNG
(US9079906, 161)
Show SMILES CCC(CC)Oc1cc(C)c2nn(CC(=O)c3cc(OCCO)cc(c3)S(F)(F)(F)(F)F)c(=N)n2n1
Show InChI InChI=1S/C21H26F5N5O4S/c1-4-15(5-2)35-19-8-13(3)20-29-30(21(27)31(20)28-19)12-18(33)14-9-16(34-7-6-32)11-17(10-14)36(22,23,24,25)26/h8-11,15,27,32H,4-7,12H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 365n/an/an/an/a7.525



Sanofi

US Patent


Assay Description
The synthesized substances were examined in a PAR1 binding test. This tested whether the substances can inhibit the binding of a radioactively labele...


US Patent US9079906 (2015)


BindingDB Entry DOI: 10.7270/Q2251GZP
More data for this
Ligand-Target Pair
Proteinase-activated receptor 1


(Homo sapiens (Human))
BDBM169647
PNG
(US9079906, 222)
Show SMILES CCOc1nn2c(nn(CC(=O)c3cc(OCCCF)cc(c3)C(C)(C)C)c2=N)c(C)c1C
Show InChI InChI=1S/C24H32FN5O3/c1-7-32-22-16(3)15(2)21-27-29(23(26)30(21)28-22)14-20(31)17-11-18(24(4,5)6)13-19(12-17)33-10-8-9-25/h11-13,26H,7-10,14H2,1-6H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 416n/an/an/an/a7.525



Sanofi

US Patent


Assay Description
The synthesized substances were examined in a PAR1 binding test. This tested whether the substances can inhibit the binding of a radioactively labele...


US Patent US9079906 (2015)


BindingDB Entry DOI: 10.7270/Q2251GZP
More data for this
Ligand-Target Pair
Proteinase-activated receptor 1


(Homo sapiens (Human))
BDBM169651
PNG
(US9079906, 240)
Show SMILES CC(C)Oc1cc(OC(C)C)c2nn(CC(=O)c3cc(OCCO)cc(c3)C(C)(C)C)c(=N)n2n1
Show InChI InChI=1S/C25H35N5O5/c1-15(2)34-21-13-22(35-16(3)4)27-30-23(21)28-29(24(30)26)14-20(32)17-10-18(25(5,6)7)12-19(11-17)33-9-8-31/h10-13,15-16,26,31H,8-9,14H2,1-7H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 484n/an/an/an/a7.525



Sanofi

US Patent


Assay Description
The synthesized substances were examined in a PAR1 binding test. This tested whether the substances can inhibit the binding of a radioactively labele...


US Patent US9079906 (2015)


BindingDB Entry DOI: 10.7270/Q2251GZP
More data for this
Ligand-Target Pair
Proteinase-activated receptor 1


(Homo sapiens (Human))
BDBM169627
PNG
(US9079906, 50)
Show SMILES CCC(CC)Oc1ccc2nn(CC(=O)c3cc(OCCOC)cc(c3)C(C)(C)C)c(=N)n2n1
Show InChI InChI=1S/C25H35N5O4/c1-7-19(8-2)34-23-10-9-22-27-29(24(26)30(22)28-23)16-21(31)17-13-18(25(3,4)5)15-20(14-17)33-12-11-32-6/h9-10,13-15,19,26H,7-8,11-12,16H2,1-6H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 631n/an/an/an/a7.525



Sanofi

US Patent


Assay Description
The synthesized substances were examined in a PAR1 binding test. This tested whether the substances can inhibit the binding of a radioactively labele...


US Patent US9079906 (2015)


BindingDB Entry DOI: 10.7270/Q2251GZP
More data for this
Ligand-Target Pair
Proteinase-activated receptor 1


(Homo sapiens (Human))
BDBM169635
PNG
(US9079906, 144)
Show SMILES CCOc1nn2c(cc1CC)nn(CC(=O)c1cc(N3CCOCC3)c(OC)c(c1)C(C)(C)C)c2=N
Show InChI InChI=1S/C26H36N6O4/c1-7-17-15-22-28-31(25(27)32(22)29-24(17)36-8-2)16-21(33)18-13-19(26(3,4)5)23(34-6)20(14-18)30-9-11-35-12-10-30/h13-15,27H,7-12,16H2,1-6H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 827n/an/an/an/a7.525



Sanofi

US Patent


Assay Description
The synthesized substances were examined in a PAR1 binding test. This tested whether the substances can inhibit the binding of a radioactively labele...


US Patent US9079906 (2015)


BindingDB Entry DOI: 10.7270/Q2251GZP
More data for this
Ligand-Target Pair
Proteinase-activated receptor 1


(Homo sapiens (Human))
BDBM169629
PNG
(US9079906, 76)
Show SMILES CCC(CC)Oc1nn2c(cc1C)nn(CC(=O)c1cc(OC)cc(c1)C(C)(C)C)c2=N
Show InChI InChI=1S/C24H33N5O3/c1-8-18(9-2)32-22-15(3)10-21-26-28(23(25)29(21)27-22)14-20(30)16-11-17(24(4,5)6)13-19(12-16)31-7/h10-13,18,25H,8-9,14H2,1-7H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 951n/an/an/an/a7.525



Sanofi

US Patent


Assay Description
The synthesized substances were examined in a PAR1 binding test. This tested whether the substances can inhibit the binding of a radioactively labele...


US Patent US9079906 (2015)


BindingDB Entry DOI: 10.7270/Q2251GZP
More data for this
Ligand-Target Pair
Proteinase-activated receptor 1


(Homo sapiens (Human))
BDBM169626
PNG
(US9079906, 26)
Show SMILES CCC(CC)Oc1ccc2nn(CC(=O)c3cc(OCC4CC4)cc(c3)C(C)(C)C)c(=N)n2n1
Show InChI InChI=1S/C26H35N5O3/c1-6-20(7-2)34-24-11-10-23-28-30(25(27)31(23)29-24)15-22(32)18-12-19(26(3,4)5)14-21(13-18)33-16-17-8-9-17/h10-14,17,20,27H,6-9,15-16H2,1-5H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 1.10E+3n/an/an/an/a7.525



Sanofi

US Patent


Assay Description
The synthesized substances were examined in a PAR1 binding test. This tested whether the substances can inhibit the binding of a radioactively labele...


US Patent US9079906 (2015)


BindingDB Entry DOI: 10.7270/Q2251GZP
More data for this
Ligand-Target Pair
Proteinase-activated receptor 1


(Homo sapiens (Human))
BDBM169649
PNG
(US9079906, 236)
Show SMILES Cc1cc(OCC2(C)COC2)nn2c1nn(CC(=O)c1cc(OCCO)cc(c1)C(C)(C)C)c2=N
Show InChI InChI=1S/C25H33N5O5/c1-16-8-21(35-15-25(5)13-33-14-25)27-30-22(16)28-29(23(30)26)12-20(32)17-9-18(24(2,3)4)11-19(10-17)34-7-6-31/h8-11,26,31H,6-7,12-15H2,1-5H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 1.40E+3n/an/an/an/a7.525



Sanofi

US Patent


Assay Description
The synthesized substances were examined in a PAR1 binding test. This tested whether the substances can inhibit the binding of a radioactively labele...


US Patent US9079906 (2015)


BindingDB Entry DOI: 10.7270/Q2251GZP
More data for this
Ligand-Target Pair
Proteinase-activated receptor 1


(Homo sapiens (Human))
BDBM169632
PNG
(US9079906, 101)
Show SMILES COCCCOc1cc(cc(c1)C(C)(C)C)C(=O)Cn1nc2c(C)cc(OCCO)nn2c1=N
Show InChI InChI=1S/C24H33N5O5/c1-16-11-21(34-10-7-30)26-29-22(16)27-28(23(29)25)15-20(31)17-12-18(24(2,3)4)14-19(13-17)33-9-6-8-32-5/h11-14,25,30H,6-10,15H2,1-5H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 1.40E+3n/an/an/an/a7.525



Sanofi

US Patent


Assay Description
The synthesized substances were examined in a PAR1 binding test. This tested whether the substances can inhibit the binding of a radioactively labele...


US Patent US9079906 (2015)


BindingDB Entry DOI: 10.7270/Q2251GZP
More data for this
Ligand-Target Pair
Proteinase-activated receptor 1


(Homo sapiens (Human))
BDBM169634
PNG
(US9079906, 127)
Show SMILES CCOc1cc(C)c2nn(CC(=O)c3cc(OC(COC)COC)cc(c3)C(C)(C)C)c(=N)n2n1
Show InChI InChI=1S/C25H35N5O5/c1-8-34-22-9-16(2)23-28-29(24(26)30(23)27-22)13-21(31)17-10-18(25(3,4)5)12-19(11-17)35-20(14-32-6)15-33-7/h9-12,20,26H,8,13-15H2,1-7H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 2.50E+3n/an/an/an/a7.525



Sanofi

US Patent


Assay Description
The synthesized substances were examined in a PAR1 binding test. This tested whether the substances can inhibit the binding of a radioactively labele...


US Patent US9079906 (2015)


BindingDB Entry DOI: 10.7270/Q2251GZP
More data for this
Ligand-Target Pair
Proteinase-activated receptor 1


(Homo sapiens (Human))
BDBM169630
PNG
(US9079906, 84)
Show SMILES CCOc1nn2c(cc1N(CC)CC)nn(CC(=O)c1cc(OC)cc(c1)S(F)(F)(F)(F)F)c2=N
Show InChI InChI=1S/C20H25F5N6O3S/c1-5-29(6-2)16-11-18-27-30(20(26)31(18)28-19(16)34-7-3)12-17(32)13-8-14(33-4)10-15(9-13)35(21,22,23,24)25/h8-11,26H,5-7,12H2,1-4H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 9.80E+3n/an/an/an/a7.525



Sanofi

US Patent


Assay Description
The synthesized substances were examined in a PAR1 binding test. This tested whether the substances can inhibit the binding of a radioactively labele...


US Patent US9079906 (2015)


BindingDB Entry DOI: 10.7270/Q2251GZP
More data for this
Ligand-Target Pair
Proteinase-activated receptor 1


(Homo sapiens (Human))
BDBM169628
PNG
(US9079906, 56)
Show SMILES COc1c(cc(cc1C(C)(C)C)C(=O)Cn1nc2ccc(Cl)nn2c1=N)N1CCOCC1
Show InChI InChI=1S/C22H27ClN6O3/c1-22(2,3)15-11-14(12-16(20(15)31-4)27-7-9-32-10-8-27)17(30)13-28-21(24)29-19(26-28)6-5-18(23)25-29/h5-6,11-12,24H,7-10,13H2,1-4H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 2.40E+4n/an/an/an/a7.525



Sanofi

US Patent


Assay Description
The synthesized substances were examined in a PAR1 binding test. This tested whether the substances can inhibit the binding of a radioactively labele...


US Patent US9079906 (2015)


BindingDB Entry DOI: 10.7270/Q2251GZP
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%