Affinity Data by Patent

Patent code US9422261

Found 11 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Polyphenol oxidase 1 (Agaricus bisporus (White button mushroom))	BDBM240726 (US9422261, Compound 4) Show SMILES CC(c1ccsc1)c1ccc(O)cc1O Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	80	n/a	n/a	n/a	n/a	6.8	n/a
PIERRE FABRE DERMO-COSMETIQUE US Patent					Assay Description Reader: Synergy HT program: tyrosinase 280-490 kinetics: kinetics over 45 minutes, reading at t=10 minutes, Tests in transparent 96-well plates, Phos...				US Patent US9422261 (2016) BindingDB Entry DOI: 10.7270/Q2PG1QMS
PIERRE FABRE DERMO-COSMETIQUE US Patent					More data for this Ligand-Target Pair
Polyphenol oxidase 1 (Agaricus bisporus (White button mushroom))	BDBM240723 (US9422261, Compound 1) Show SMILES CC(c1cccs1)c1ccc(O)cc1O Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	90	n/a	n/a	n/a	n/a	6.8	n/a
PIERRE FABRE DERMO-COSMETIQUE US Patent					Assay Description Reader: Synergy HT program: tyrosinase 280-490 kinetics: kinetics over 45 minutes, reading at t=10 minutes, Tests in transparent 96-well plates, Phos...				US Patent US9422261 (2016) BindingDB Entry DOI: 10.7270/Q2PG1QMS
PIERRE FABRE DERMO-COSMETIQUE US Patent					More data for this Ligand-Target Pair
Polyphenol oxidase 1 (Agaricus bisporus (White button mushroom))	BDBM240731 (US9422261, 4-(1- phenylethyl) benzene-1,3- diol) Show SMILES CC(c1ccccc1)c1ccc(O)cc1O Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	6.8	n/a
PIERRE FABRE DERMO-COSMETIQUE US Patent					Assay Description Reader: Synergy HT program: tyrosinase 280-490 kinetics: kinetics over 45 minutes, reading at t=10 minutes, Tests in transparent 96-well plates, Phos...				US Patent US9422261 (2016) BindingDB Entry DOI: 10.7270/Q2PG1QMS
PIERRE FABRE DERMO-COSMETIQUE US Patent					More data for this Ligand-Target Pair
Polyphenol oxidase 1 (Agaricus bisporus (White button mushroom))	BDBM240725 (US9422261, Compound 3) Show SMILES CC(c1cccnc1)c1ccc(O)cc1O Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	200	n/a	n/a	n/a	n/a	6.8	n/a
PIERRE FABRE DERMO-COSMETIQUE US Patent					Assay Description Reader: Synergy HT program: tyrosinase 280-490 kinetics: kinetics over 45 minutes, reading at t=10 minutes, Tests in transparent 96-well plates, Phos...				US Patent US9422261 (2016) BindingDB Entry DOI: 10.7270/Q2PG1QMS
PIERRE FABRE DERMO-COSMETIQUE US Patent					More data for this Ligand-Target Pair
Polyphenol oxidase 1 (Agaricus bisporus (White button mushroom))	BDBM240724 (US9422261, Compound 2) Show SMILES CC(c1ccccn1)c1ccc(O)cc1O Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	400	n/a	n/a	n/a	n/a	6.8	n/a
PIERRE FABRE DERMO-COSMETIQUE US Patent					Assay Description Reader: Synergy HT program: tyrosinase 280-490 kinetics: kinetics over 45 minutes, reading at t=10 minutes, Tests in transparent 96-well plates, Phos...				US Patent US9422261 (2016) BindingDB Entry DOI: 10.7270/Q2PG1QMS
PIERRE FABRE DERMO-COSMETIQUE US Patent					More data for this Ligand-Target Pair
Polyphenol oxidase 1 (Agaricus bisporus (White button mushroom))	BDBM50248158 (CHEMBL450195 \| N-butylresorcinol \| US8993596, 4-Bu...) Show SMILES CCCCc1ccc(O)cc1O Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	6.8	n/a
PIERRE FABRE DERMO-COSMETIQUE US Patent					Assay Description Reader: Synergy HT program: tyrosinase 280-490 kinetics: kinetics over 45 minutes, reading at t=10 minutes, Tests in transparent 96-well plates, Phos...				US Patent US9422261 (2016) BindingDB Entry DOI: 10.7270/Q2PG1QMS
PIERRE FABRE DERMO-COSMETIQUE US Patent					More data for this Ligand-Target Pair
Polyphenol oxidase 1 (Agaricus bisporus (White button mushroom))	BDBM240727 (US9422261, Compound 5) Show SMILES CC(c1nccs1)c1ccc(O)cc1O Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	6.8	n/a
PIERRE FABRE DERMO-COSMETIQUE US Patent					Assay Description Reader: Synergy HT program: tyrosinase 280-490 kinetics: kinetics over 45 minutes, reading at t=10 minutes, Tests in transparent 96-well plates, Phos...				US Patent US9422261 (2016) BindingDB Entry DOI: 10.7270/Q2PG1QMS
PIERRE FABRE DERMO-COSMETIQUE US Patent					More data for this Ligand-Target Pair
Polyphenol oxidase 1 (Agaricus bisporus (White button mushroom))	BDBM240729 (US9422261, Unigen resorcinol derivative \| US968291...) Show SMILES Oc1ccc(Cc2cccnc2)c(O)c1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	6.8	n/a
PIERRE FABRE DERMO-COSMETIQUE US Patent					Assay Description Reader: Synergy HT program: tyrosinase 280-490 kinetics: kinetics over 45 minutes, reading at t=10 minutes, Tests in transparent 96-well plates, Phos...				US Patent US9422261 (2016) BindingDB Entry DOI: 10.7270/Q2PG1QMS
PIERRE FABRE DERMO-COSMETIQUE US Patent					More data for this Ligand-Target Pair
Polyphenol oxidase 1 (Agaricus bisporus (White button mushroom))	BDBM240730 (US9422261, Unigen resorcinol derivative \| US968291...) Show SMILES OC(c1cccnc1)c1ccc(O)cc1O Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	6.8	n/a
PIERRE FABRE DERMO-COSMETIQUE US Patent					Assay Description Reader: Synergy HT program: tyrosinase 280-490 kinetics: kinetics over 45 minutes, reading at t=10 minutes, Tests in transparent 96-well plates, Phos...				US Patent US9422261 (2016) BindingDB Entry DOI: 10.7270/Q2PG1QMS
PIERRE FABRE DERMO-COSMETIQUE US Patent					More data for this Ligand-Target Pair
Polyphenol oxidase 1 (Agaricus bisporus (White button mushroom))	BDBM50031467 (5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE \| 5-Hyd...) Show SMILES OCc1cc(=O)c(O)co1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	US Patent	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	6.8	n/a
PIERRE FABRE DERMO-COSMETIQUE US Patent					Assay Description Reader: Synergy HT program: tyrosinase 280-490 kinetics: kinetics over 45 minutes, reading at t=10 minutes, Tests in transparent 96-well plates, Phos...				US Patent US9422261 (2016) BindingDB Entry DOI: 10.7270/Q2PG1QMS
PIERRE FABRE DERMO-COSMETIQUE US Patent					More data for this Ligand-Target Pair
Polyphenol oxidase 1 (Agaricus bisporus (White button mushroom))	BDBM240728 (US9422261, Arbutin) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	9.00E+4	n/a	n/a	n/a	n/a	6.8	n/a
PIERRE FABRE DERMO-COSMETIQUE US Patent					Assay Description Reader: Synergy HT program: tyrosinase 280-490 kinetics: kinetics over 45 minutes, reading at t=10 minutes, Tests in transparent 96-well plates, Phos...				US Patent US9422261 (2016) BindingDB Entry DOI: 10.7270/Q2PG1QMS
PIERRE FABRE DERMO-COSMETIQUE US Patent					More data for this Ligand-Target Pair

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* indicates data uncertainty>20%