BDBM50248158 CHEMBL450195::N-butylresorcinol::US8993596, 4-Butylresorcinol (Rucinol)::US9422261, 4-Butyl- resorcinol

SMILES: CCCCc1ccc(O)cc1O

InChI Key: InChIKey=CSHZYWUPJWVTMQ-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50248158   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosinase (Mus musculus (Mouse))	BDBM50248158 (CHEMBL450195 | N-butylresorcinol | US8993596, 4-Bu...) Show SMILES CCCCc1ccc(O)cc1O Show InChI InChI=1S/C10H14O2/c1-2-3-4-8-5-6-9(11)7-10(8)12/h5-7,11-12H,2-4H2,1H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	6.8	37
Galderma Research & Development US Patent					Assay Description The activity of the inhibitors is measured using a lysate of B16F1 cells (murine melanoma line). In the presence of the L-tyrosine substrate, the tyr...				US Patent US8993596 (2015) BindingDB Entry DOI: 10.7270/Q2HD7TDC
					More data for this Ligand-Target Pair
Tyrosinase (Agaricus bisporus (White button mushroom))	BDBM50248158 (CHEMBL450195 | N-butylresorcinol | US8993596, 4-Bu...) Show SMILES CCCCc1ccc(O)cc1O Show InChI InChI=1S/C10H14O2/c1-2-3-4-8-5-6-9(11)7-10(8)12/h5-7,11-12H,2-4H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	6.8	n/a
PIERRE FABRE DERMO-COSMETIQUE US Patent					Assay Description Reader: Synergy HT program: tyrosinase 280-490 kinetics: kinetics over 45 minutes, reading at t=10 minutes, Tests in transparent 96-well plates, Phos...				US Patent US9422261 (2016) BindingDB Entry DOI: 10.7270/Q2PG1QMS
					More data for this Ligand-Target Pair
Tyrosinase (Homo sapiens (Human))	BDBM50248158 (CHEMBL450195 | N-butylresorcinol | US8993596, 4-Bu...) Show SMILES CCCCc1ccc(O)cc1O Show InChI InChI=1S/C10H14O2/c1-2-3-4-8-5-6-9(11)7-10(8)12/h5-7,11-12H,2-4H2,1H3	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human tyrosinase				J Med Chem 61: 7395-7418 (2018) Article DOI: 10.1021/acs.jmedchem.7b00967
					More data for this Ligand-Target Pair
Tyrosinase (Homo sapiens (Human))	BDBM50248158 (CHEMBL450195 | N-butylresorcinol | US8993596, 4-Bu...) Show SMILES CCCCc1ccc(O)cc1O Show InChI InChI=1S/C10H14O2/c1-2-3-4-8-5-6-9(11)7-10(8)12/h5-7,11-12H,2-4H2,1H3	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of human tyrosinase				J Med Chem 61: 7395-7418 (2018) Article DOI: 10.1021/acs.jmedchem.7b00967
					More data for this Ligand-Target Pair
Tyrosinase (Agaricus bisporus (Common mushroom))	BDBM50248158 (CHEMBL450195 | N-butylresorcinol | US8993596, 4-Bu...) Show SMILES CCCCc1ccc(O)cc1O Show InChI InChI=1S/C10H14O2/c1-2-3-4-8-5-6-9(11)7-10(8)12/h5-7,11-12H,2-4H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
AmorePacific Corporation Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase activity after 20 mins				Bioorg Med Chem Lett 19: 1532-3 (2009) Article DOI: 10.1016/j.bmcl.2008.12.106 BindingDB Entry DOI: 10.7270/Q2KK9BNT
					More data for this Ligand-Target Pair