Affinity Data by Patent

Patent code US9221824

Found 5 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM98028 (US10472367, Compound Formula II \| US10919901, Comp...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.550	n/a	n/a	n/a	n/a	7.5	30
Incyte Holdings Corporation; Incyte Corporation US Patent					Assay Description The compounds of the invention were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values for the inhibition of c-M...				US Patent US9221824 (2015) BindingDB Entry DOI: 10.7270/Q2MP524M
Incyte Holdings Corporation; Incyte Corporation US Patent					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM98030 (US10472367, Compound Formula IV \| US10919901, Comp...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.550	n/a	n/a	n/a	n/a	7.5	30
Incyte Holdings Corporation; Incyte Corporation US Patent					Assay Description The compounds of the invention were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values for the inhibition of c-M...				US Patent US9221824 (2015) BindingDB Entry DOI: 10.7270/Q2MP524M
Incyte Holdings Corporation; Incyte Corporation US Patent					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM98029 (US10472367, Compound Formula III \| US10919901, Com...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.550	n/a	n/a	n/a	n/a	7.5	30
Incyte Holdings Corporation; Incyte Corporation US Patent					Assay Description The compounds of the invention were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values for the inhibition of c-M...				US Patent US9221824 (2015) BindingDB Entry DOI: 10.7270/Q2MP524M
Incyte Holdings Corporation; Incyte Corporation US Patent					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM98031 (US10472367, Compound Formula V \| US10919901, Compo...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.550	n/a	n/a	n/a	n/a	7.5	30
Incyte Holdings Corporation; Incyte Corporation US Patent					Assay Description The compounds of the invention were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values for the inhibition of c-M...				US Patent US9221824 (2015) BindingDB Entry DOI: 10.7270/Q2MP524M
Incyte Holdings Corporation; Incyte Corporation US Patent					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM98027 (US10472367, Compound Formula I \| US10919901, Compo...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.550	n/a	n/a	n/a	n/a	7.5	30
Incyte Holdings Corporation; Incyte Corporation US Patent					Assay Description The compounds of the invention were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values for the inhibition of c-M...				US Patent US9221824 (2015) BindingDB Entry DOI: 10.7270/Q2MP524M
Incyte Holdings Corporation; Incyte Corporation US Patent					More data for this Ligand-Target Pair

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* indicates data uncertainty>20%