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Patent code US9133134

Compile Data Set for Download or QSAR
Found 1 hit of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase BTK


(Homo sapiens (Human))		BDBM50043319
PNG
(CHEMBL3355049 | US9133134, 4)
Show SMILES COCCOc1ccc(Nc2ncc(F)c(Nc3cccc(NC(=O)C(O)CO)c3)n2)cc1
Show InChI InChI=1S/C22H24FN5O5/c1-32-9-10-33-17-7-5-14(6-8-17)27-22-24-12-18(23)20(28-22)25-15-3-2-4-16(11-15)26-21(31)19(30)13-29/h2-8,11-12,19,29-30H,9-10,13H2,1H3,(H,26,31)(H2,24,25,27,28)
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Similars
US Patent
n/an/a<500n/an/an/an/an/an/a



PHARMACYCLICS LLC

US Patent


Assay Description
Kinase activity is measured in vitro using electrophoretic mobility shift assay. The kinase reactions are assembled in a total volume of 25 uL in 384...

US Patent US9133134 (2015)


BindingDB Entry DOI: 10.7270/Q2ZK5FF8
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%