Found 52 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM99943
(US8501750, 56)Show SMILES CCc1cc2c(s1)n(Cc1ccc(cc1)-c1ccccc1-c1nc(=O)o[nH]1)c(=O)n(CCc1ccc(F)cc1)c2=O Show InChI InChI=1S/C31H25FN4O4S/c1-2-23-17-26-28(37)35(16-15-19-9-13-22(32)14-10-19)31(39)36(29(26)41-23)18-20-7-11-21(12-8-20)24-5-3-4-6-25(24)27-33-30(38)40-34-27/h3-14,17H,2,15-16,18H2,1H3,(H,33,34,38) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 0.340 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description
Binding assay using human AT1. |
US Patent US8501750 (2013)
BindingDB Entry DOI: 10.7270/Q2F76B5Q |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM99950
(US8501750, 83)Show SMILES CCc1cc2c(s1)n(Cc1ccc(cc1F)-c1ccccc1-c1nc(=O)o[nH]1)c(=O)n(CC(=O)c1ccc(OC)cc1)c2=O Show InChI InChI=1S/C32H25FN4O6S/c1-3-22-15-25-29(39)36(17-27(38)18-10-12-21(42-2)13-11-18)32(41)37(30(25)44-22)16-20-9-8-19(14-26(20)33)23-6-4-5-7-24(23)28-34-31(40)43-35-28/h4-15H,3,16-17H2,1-2H3,(H,34,35,40) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 0.770 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description
Binding assay using human AT1. |
US Patent US8501750 (2013)
BindingDB Entry DOI: 10.7270/Q2F76B5Q |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM99946
(US8501750, 60)Show SMILES Fc1cccc(CCn2c(=O)n(Cc3ccc(cc3)-c3ccccc3-c3nc(=O)o[nH]3)c3sc(CC(F)(F)F)cc3c2=O)c1 Show InChI InChI=1S/C31H22F4N4O4S/c32-21-5-3-4-18(14-21)12-13-38-27(40)25-15-22(16-31(33,34)35)44-28(25)39(30(38)42)17-19-8-10-20(11-9-19)23-6-1-2-7-24(23)26-36-29(41)43-37-26/h1-11,14-15H,12-13,16-17H2,(H,36,37,41) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description
Binding assay using human AT1. |
US Patent US8501750 (2013)
BindingDB Entry DOI: 10.7270/Q2F76B5Q |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM99952
(US8501750, 105)Show SMILES COc1ccc(cc1)C(=O)Cn1c(=O)n(Cc2ccc(cc2F)-c2ccccc2-c2noc(O)n2)c2sc(cc2c1=O)C1CC1 Show InChI InChI=1S/C33H25FN4O6S/c1-43-22-12-10-18(11-13-22)27(39)17-37-30(40)25-15-28(19-6-7-19)45-31(25)38(33(37)42)16-21-9-8-20(14-26(21)34)23-4-2-3-5-24(23)29-35-32(41)44-36-29/h2-5,8-15,19H,6-7,16-17H2,1H3,(H,35,36,41)/p-1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description
Binding assay using human AT1. |
US Patent US8501750 (2013)
BindingDB Entry DOI: 10.7270/Q2F76B5Q |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM99949
(US8501750, 76)Show SMILES CCc1cc2c(s1)n(Cc1ccc(cc1)-c1ccccc1-c1nc(=O)o[nH]1)c(=O)n(CC(=O)c1ccc(OC)cc1C)c2=O Show InChI InChI=1S/C33H28N4O6S/c1-4-23-16-27-30(39)36(18-28(38)24-14-13-22(42-3)15-19(24)2)33(41)37(31(27)44-23)17-20-9-11-21(12-10-20)25-7-5-6-8-26(25)29-34-32(40)43-35-29/h5-16H,4,17-18H2,1-3H3,(H,34,35,40) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description
Binding assay using human AT1. |
US Patent US8501750 (2013)
BindingDB Entry DOI: 10.7270/Q2F76B5Q |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM99947
(US8501750, 63)Show SMILES Fc1ccc(cc1)C(=O)Cn1c(=O)n(Cc2ccc(cc2)-c2ccccc2-c2nc(=O)o[nH]2)c2sc(cc2c1=O)C1CC1 Show InChI InChI=1S/C32H23FN4O5S/c33-22-13-11-20(12-14-22)26(38)17-36-29(39)25-15-27(21-9-10-21)43-30(25)37(32(36)41)16-18-5-7-19(8-6-18)23-3-1-2-4-24(23)28-34-31(40)42-35-28/h1-8,11-15,21H,9-10,16-17H2,(H,34,35,40) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description
Binding assay using human AT1. |
US Patent US8501750 (2013)
BindingDB Entry DOI: 10.7270/Q2F76B5Q |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM99953
(US8501750, 107)Show SMILES COc1cccc(c1)C(=O)Cn1c(=O)n(Cc2ccc(cc2)-c2ccccc2-c2noc(O)n2)c2sc(cc2c1=O)C1CC1 Show InChI InChI=1S/C33H26N4O6S/c1-42-23-6-4-5-22(15-23)27(38)18-36-30(39)26-16-28(21-13-14-21)44-31(26)37(33(36)41)17-19-9-11-20(12-10-19)24-7-2-3-8-25(24)29-34-32(40)43-35-29/h2-12,15-16,21H,13-14,17-18H2,1H3,(H,34,35,40)/p-1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description
Binding assay using human AT1. |
US Patent US8501750 (2013)
BindingDB Entry DOI: 10.7270/Q2F76B5Q |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM99951
(US8501750, 99)Show SMILES COc1ccccc1C(=O)Cn1c(=O)n(Cc2ccc(cc2)-c2ccccc2-c2noc(O)n2)c2sc(cc2c1=O)C1CC1 Show InChI InChI=1S/C33H26N4O6S/c1-42-27-9-5-4-8-24(27)26(38)18-36-30(39)25-16-28(21-14-15-21)44-31(25)37(33(36)41)17-19-10-12-20(13-11-19)22-6-2-3-7-23(22)29-34-32(40)43-35-29/h2-13,16,21H,14-15,17-18H2,1H3,(H,34,35,40)/p-1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description
Binding assay using human AT1. |
US Patent US8501750 (2013)
BindingDB Entry DOI: 10.7270/Q2F76B5Q |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM99961
(US8501750, 131)Show SMILES CCc1cc2c(s1)n(Cc1ccc(cc1)-c1ccccc1-c1nc(=O)o[nH]1)c(=O)n(CC(=O)C(C)(C)C)c2=O Show InChI InChI=1S/C29H28N4O5S/c1-5-19-14-22-25(35)32(16-23(34)29(2,3)4)28(37)33(26(22)39-19)15-17-10-12-18(13-11-17)20-8-6-7-9-21(20)24-30-27(36)38-31-24/h6-14H,5,15-16H2,1-4H3,(H,30,31,36) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description
Binding assay using human AT1. |
US Patent US8501750 (2013)
BindingDB Entry DOI: 10.7270/Q2F76B5Q |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM99980
(US8501750, 181)Show SMILES CCc1cc2c(s1)n(Cc1ccc(cc1F)-c1ccccc1-c1nc(=O)o[nH]1)c(=O)n(-c1ccc3OC(C)(C)Cc3c1)c2=O Show InChI InChI=1S/C33H27FN4O5S/c1-4-22-15-25-29(39)38(21-11-12-27-20(13-21)16-33(2,3)42-27)32(41)37(30(25)44-22)17-19-10-9-18(14-26(19)34)23-7-5-6-8-24(23)28-35-31(40)43-36-28/h5-15H,4,16-17H2,1-3H3,(H,35,36,40) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description
Binding assay using human AT1. |
US Patent US8501750 (2013)
BindingDB Entry DOI: 10.7270/Q2F76B5Q |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM99981
(US8501750, 186)Show SMILES CC(C)(C)C(=O)Cn1c(=O)n(Cc2ccc(cc2)-c2ccccc2-c2nc(=O)o[nH]2)c2sc(cc2c1=O)C1CC1 Show InChI InChI=1S/C30H28N4O5S/c1-30(2,3)24(35)16-33-26(36)22-14-23(19-12-13-19)40-27(22)34(29(33)38)15-17-8-10-18(11-9-17)20-6-4-5-7-21(20)25-31-28(37)39-32-25/h4-11,14,19H,12-13,15-16H2,1-3H3,(H,31,32,37) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description
Binding assay using human AT1. |
US Patent US8501750 (2013)
BindingDB Entry DOI: 10.7270/Q2F76B5Q |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM99945
(US8501750, 59)Show SMILES Cc1ccc(CCn2c(=O)n(Cc3ccc(cc3)-c3ccccc3-c3nc(=O)o[nH]3)c3sc(CC(F)(F)F)cc3c2=O)cc1 Show InChI InChI=1S/C32H25F3N4O4S/c1-19-6-8-20(9-7-19)14-15-38-28(40)26-16-23(17-32(33,34)35)44-29(26)39(31(38)42)18-21-10-12-22(13-11-21)24-4-2-3-5-25(24)27-36-30(41)43-37-27/h2-13,16H,14-15,17-18H2,1H3,(H,36,37,41) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description
Binding assay using human AT1. |
US Patent US8501750 (2013)
BindingDB Entry DOI: 10.7270/Q2F76B5Q |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM99992
(US8501750, 215)Show SMILES CCc1cc2c(s1)n(Cc1ccc(cc1)-c1ccccc1-c1nc(=O)o[nH]1)c(=O)n(CC(=NOC)c1ccccc1)c2=O Show InChI InChI=1S/C32H27N5O5S/c1-3-23-17-26-29(38)36(19-27(34-41-2)22-9-5-4-6-10-22)32(40)37(30(26)43-23)18-20-13-15-21(16-14-20)24-11-7-8-12-25(24)28-33-31(39)42-35-28/h4-17H,3,18-19H2,1-2H3,(H,33,35,39) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description
Binding assay using human AT1. |
US Patent US8501750 (2013)
BindingDB Entry DOI: 10.7270/Q2F76B5Q |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM99974
(US8501750, 153)Show SMILES CCc1cc2c(s1)n(Cc1ccc(cc1F)-c1ccccc1-c1nc(=O)o[nH]1)c(=O)n(CC(OC(C)=O)c1ccc(OC)cc1)c2=O Show InChI InChI=1S/C34H29FN4O7S/c1-4-24-16-27-31(41)38(18-29(45-19(2)40)20-11-13-23(44-3)14-12-20)34(43)39(32(27)47-24)17-22-10-9-21(15-28(22)35)25-7-5-6-8-26(25)30-36-33(42)46-37-30/h5-16,29H,4,17-18H2,1-3H3,(H,36,37,42) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description
Binding assay using human AT1. |
US Patent US8501750 (2013)
BindingDB Entry DOI: 10.7270/Q2F76B5Q |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM99984
(US8501750, 197)Show SMILES CCc1cc2c(s1)n(Cc1c(F)cc(cc1F)-c1ccccc1-c1nc(=O)o[nH]1)c(=O)n(CC(=O)c1ccc(OC)cc1)c2=O Show InChI InChI=1S/C32H24F2N4O6S/c1-3-20-14-23-29(40)37(16-27(39)17-8-10-19(43-2)11-9-17)32(42)38(30(23)45-20)15-24-25(33)12-18(13-26(24)34)21-6-4-5-7-22(21)28-35-31(41)44-36-28/h4-14H,3,15-16H2,1-2H3,(H,35,36,41) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description
Binding assay using human AT1. |
US Patent US8501750 (2013)
BindingDB Entry DOI: 10.7270/Q2F76B5Q |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM99993
(US8501750, 221)Show SMILES CCc1cc2c(s1)n(Cc1ccc(cc1)-c1ccccc1-c1nc(=O)o[nH]1)c(=O)n(CC(=O)c1cccs1)c2=O Show InChI InChI=1S/C29H22N4O5S2/c1-2-19-14-22-26(35)32(16-23(34)24-8-5-13-39-24)29(37)33(27(22)40-19)15-17-9-11-18(12-10-17)20-6-3-4-7-21(20)25-30-28(36)38-31-25/h3-14H,2,15-16H2,1H3,(H,30,31,36) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description
Binding assay using human AT1. |
US Patent US8501750 (2013)
BindingDB Entry DOI: 10.7270/Q2F76B5Q |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM99967
(US8501750, 143)Show SMILES CC(C)(C)C(O)Cn1c(=O)n(Cc2ccc(cc2)-c2ccccc2-c2nc(=O)o[nH]2)c2sc(cc2c1=O)C1CC1 Show InChI InChI=1S/C30H30N4O5S/c1-30(2,3)24(35)16-33-26(36)22-14-23(19-12-13-19)40-27(22)34(29(33)38)15-17-8-10-18(11-9-17)20-6-4-5-7-21(20)25-31-28(37)39-32-25/h4-11,14,19,24,35H,12-13,15-16H2,1-3H3,(H,31,32,37) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description
Binding assay using human AT1. |
US Patent US8501750 (2013)
BindingDB Entry DOI: 10.7270/Q2F76B5Q |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM99977
(US8501750, 157)Show SMILES CCc1cc2c(s1)n(Cc1ccc(cc1F)-c1ccccc1-c1noc(=O)[nH]1)c(=O)n(CC(=O)c1ccc(OC)c(F)c1)c2=O Show InChI InChI=1S/C32H24F2N4O6S/c1-3-20-14-23-29(40)37(16-26(39)18-10-11-27(43-2)25(34)13-18)32(42)38(30(23)45-20)15-19-9-8-17(12-24(19)33)21-6-4-5-7-22(21)28-35-31(41)44-36-28/h4-14H,3,15-16H2,1-2H3,(H,35,36,41) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description
Binding assay using human AT1. |
US Patent US8501750 (2013)
BindingDB Entry DOI: 10.7270/Q2F76B5Q |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM99958
(US8501750, 127)Show SMILES COc1ccccc1C(=O)Cn1c(=O)n(Cc2c(F)cc(cc2F)-c2ccccc2-c2nc(=O)o[nH]2)c2sc(CC(F)(F)F)cc2c1=O Show InChI InChI=1S/C32H21F5N4O6S/c1-46-26-9-5-4-8-20(26)25(42)15-40-28(43)21-12-17(13-32(35,36)37)48-29(21)41(31(40)45)14-22-23(33)10-16(11-24(22)34)18-6-2-3-7-19(18)27-38-30(44)47-39-27/h2-12H,13-15H2,1H3,(H,38,39,44)/p-1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description
Binding assay using human AT1. |
US Patent US8501750 (2013)
BindingDB Entry DOI: 10.7270/Q2F76B5Q |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM99954
(US8501750, 109)Show SMILES CCc1cc2c(s1)n(Cc1ccc(cc1)-c1ccccc1-c1noc([O-])n1)c(=O)n(CC(=O)c1ccccc1OC)c2=O Show InChI InChI=1S/C32H26N4O6S/c1-3-21-16-25-29(38)35(18-26(37)24-10-6-7-11-27(24)41-2)32(40)36(30(25)43-21)17-19-12-14-20(15-13-19)22-8-4-5-9-23(22)28-33-31(39)42-34-28/h4-16H,3,17-18H2,1-2H3,(H,33,34,39)/p-1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description
Binding assay using human AT1. |
US Patent US8501750 (2013)
BindingDB Entry DOI: 10.7270/Q2F76B5Q |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM99988
(US8501750, 209)Show SMILES CCc1cc2c(s1)n(Cc1ccc(cc1)-c1ccccc1-c1nc(=O)o[nH]1)c(=O)n(CC(=O)c1ccccc1)c2=O Show InChI InChI=1S/C31H24N4O5S/c1-2-22-16-25-28(37)34(18-26(36)21-8-4-3-5-9-21)31(39)35(29(25)41-22)17-19-12-14-20(15-13-19)23-10-6-7-11-24(23)27-32-30(38)40-33-27/h3-16H,2,17-18H2,1H3,(H,32,33,38) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description
Binding assay using human AT1. |
US Patent US8501750 (2013)
BindingDB Entry DOI: 10.7270/Q2F76B5Q |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM99973
(US8501750, 152)Show SMILES CCc1cc2c(s1)n(Cc1ccc(cc1F)-c1ccccc1-c1nc(=O)o[nH]1)c(=O)n(CC(O)c1ccc(OC)cc1)c2=O Show InChI InChI=1S/C32H27FN4O6S/c1-3-22-15-25-29(39)36(17-27(38)18-10-12-21(42-2)13-11-18)32(41)37(30(25)44-22)16-20-9-8-19(14-26(20)33)23-6-4-5-7-24(23)28-34-31(40)43-35-28/h4-15,27,38H,3,16-17H2,1-2H3,(H,34,35,40) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description
Binding assay using human AT1. |
US Patent US8501750 (2013)
BindingDB Entry DOI: 10.7270/Q2F76B5Q |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM99948
(US8501750, 73)Show SMILES CCc1cc2c(s1)n(Cc1ccc(cc1)-c1ccccc1-c1nc(=O)o[nH]1)c(=O)n(CC(=O)c1ccc(OC)cc1F)c2=O Show InChI InChI=1S/C32H25FN4O6S/c1-3-21-15-25-29(39)36(17-27(38)24-13-12-20(42-2)14-26(24)33)32(41)37(30(25)44-21)16-18-8-10-19(11-9-18)22-6-4-5-7-23(22)28-34-31(40)43-35-28/h4-15H,3,16-17H2,1-2H3,(H,34,35,40) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description
Binding assay using human AT1. |
US Patent US8501750 (2013)
BindingDB Entry DOI: 10.7270/Q2F76B5Q |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM99964
(US8501750, 136)Show SMILES FC(F)(F)Cc1cc2c(s1)n(Cc1ccc(cc1)-c1ccccc1-c1nc(=O)o[nH]1)c(=O)n(CC(=O)C1CCCCC1)c2=O Show InChI InChI=1S/C31H27F3N4O5S/c32-31(33,34)15-21-14-24-27(40)37(17-25(39)20-6-2-1-3-7-20)30(42)38(28(24)44-21)16-18-10-12-19(13-11-18)22-8-4-5-9-23(22)26-35-29(41)43-36-26/h4-5,8-14,20H,1-3,6-7,15-17H2,(H,35,36,41) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description
Binding assay using human AT1. |
US Patent US8501750 (2013)
BindingDB Entry DOI: 10.7270/Q2F76B5Q |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM99985
(US8501750, 198)Show SMILES CCc1cc2c(s1)n(Cc1ccc(cc1)-c1ccc(F)cc1-c1nc(=O)o[nH]1)c(=O)n(CC(=O)c1ccc(OC)cc1)c2=O Show InChI InChI=1S/C32H25FN4O6S/c1-3-23-15-26-29(39)36(17-27(38)20-8-11-22(42-2)12-9-20)32(41)37(30(26)44-23)16-18-4-6-19(7-5-18)24-13-10-21(33)14-25(24)28-34-31(40)43-35-28/h4-15H,3,16-17H2,1-2H3,(H,34,35,40) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description
Binding assay using human AT1. |
US Patent US8501750 (2013)
BindingDB Entry DOI: 10.7270/Q2F76B5Q |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM99987
(US8501750, 205)Show SMILES CCc1cc2c(s1)n(Cc1ccc(cc1)-c1ccccc1-c1nc(=O)o[nH]1)c(=O)n(CC(=O)C1CCCCC1)c2=O Show InChI InChI=1S/C31H30N4O5S/c1-2-22-16-25-28(37)34(18-26(36)21-8-4-3-5-9-21)31(39)35(29(25)41-22)17-19-12-14-20(15-13-19)23-10-6-7-11-24(23)27-32-30(38)40-33-27/h6-7,10-16,21H,2-5,8-9,17-18H2,1H3,(H,32,33,38) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description
Binding assay using human AT1. |
US Patent US8501750 (2013)
BindingDB Entry DOI: 10.7270/Q2F76B5Q |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM99966
(US8501750, 142)Show SMILES CCc1cc2c(s1)n(Cc1ccc(cc1)-c1ccccc1-c1nc(=O)o[nH]1)c(=O)n(C\C(=N\OC)C(C)(C)C)c2=O Show InChI InChI=1S/C30H31N5O5S/c1-6-20-15-23-26(36)34(17-24(32-39-5)30(2,3)4)29(38)35(27(23)41-20)16-18-11-13-19(14-12-18)21-9-7-8-10-22(21)25-31-28(37)40-33-25/h7-15H,6,16-17H2,1-5H3,(H,31,33,37)/b32-24- | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description
Binding assay using human AT1. |
US Patent US8501750 (2013)
BindingDB Entry DOI: 10.7270/Q2F76B5Q |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM99963
(US8501750, 135)Show SMILES COc1ccc(cc1)C(=O)Cn1c(=O)n(Cc2c(F)cc(cc2F)-c2ccccc2-c2nc(=O)o[nH]2)c2sc(cc2c1=O)C1CC1 Show InChI InChI=1S/C33H24F2N4O6S/c1-44-20-10-8-17(9-11-20)27(40)16-38-30(41)23-14-28(18-6-7-18)46-31(23)39(33(38)43)15-24-25(34)12-19(13-26(24)35)21-4-2-3-5-22(21)29-36-32(42)45-37-29/h2-5,8-14,18H,6-7,15-16H2,1H3,(H,36,37,42)/p-1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description
Binding assay using human AT1. |
US Patent US8501750 (2013)
BindingDB Entry DOI: 10.7270/Q2F76B5Q |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM99970
(US8501750, 148)Show SMILES CCc1cc2c(s1)n(Cc1ccc(cc1)-c1ccccc1-c1nc(=O)o[nH]1)c(=O)n(CC(=O)C(C)(C)COC(C)=O)c2=O Show InChI InChI=1S/C31H30N4O7S/c1-5-21-14-24-27(38)34(16-25(37)31(3,4)17-41-18(2)36)30(40)35(28(24)43-21)15-19-10-12-20(13-11-19)22-8-6-7-9-23(22)26-32-29(39)42-33-26/h6-14H,5,15-17H2,1-4H3,(H,32,33,39) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description
Binding assay using human AT1. |
US Patent US8501750 (2013)
BindingDB Entry DOI: 10.7270/Q2F76B5Q |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM99972
(US8501750, 150)Show SMILES CCc1cc2c(s1)n(Cc1ccc(cc1)-c1ccccc1-c1nc(=O)o[nH]1)c(=O)n(CC(=O)c1ccc(Cl)s1)c2=O Show InChI InChI=1S/C29H21ClN4O5S2/c1-2-18-13-21-26(36)33(15-22(35)23-11-12-24(30)41-23)29(38)34(27(21)40-18)14-16-7-9-17(10-8-16)19-5-3-4-6-20(19)25-31-28(37)39-32-25/h3-13H,2,14-15H2,1H3,(H,31,32,37) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description
Binding assay using human AT1. |
US Patent US8501750 (2013)
BindingDB Entry DOI: 10.7270/Q2F76B5Q |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM99960
(US8501750, 130)Show SMILES COc1cc(F)ccc1C(=O)Cn1c(=O)n(Cc2ccc(cc2)-c2ccccc2-c2nc(=O)o[nH]2)c2sc(cc2c1=O)C1CC1 Show InChI InChI=1S/C33H25FN4O6S/c1-43-27-14-21(34)12-13-24(27)26(39)17-37-30(40)25-15-28(20-10-11-20)45-31(25)38(33(37)42)16-18-6-8-19(9-7-18)22-4-2-3-5-23(22)29-35-32(41)44-36-29/h2-9,12-15,20H,10-11,16-17H2,1H3,(H,35,36,41) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description
Binding assay using human AT1. |
US Patent US8501750 (2013)
BindingDB Entry DOI: 10.7270/Q2F76B5Q |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM99989
(US8501750, 210)Show SMILES CCO\N=C(\Cn1c(=O)n(Cc2ccc(cc2)-c2ccccc2-c2nc(=O)o[nH]2)c2sc(CC)cc2c1=O)c1ccc(OC)cc1 Show InChI InChI=1S/C34H31N5O6S/c1-4-25-18-28-31(40)38(20-29(36-44-5-2)23-14-16-24(43-3)17-15-23)34(42)39(32(28)46-25)19-21-10-12-22(13-11-21)26-8-6-7-9-27(26)30-35-33(41)45-37-30/h6-18H,4-5,19-20H2,1-3H3,(H,35,37,41)/b36-29- | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description
Binding assay using human AT1. |
US Patent US8501750 (2013)
BindingDB Entry DOI: 10.7270/Q2F76B5Q |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM99944
(US8501750, 58)Show SMILES FC(F)(F)Cc1cc2c(s1)n(Cc1ccc(cc1)-c1ccccc1-c1nc(=O)o[nH]1)c(=O)n(CCc1ccc(Cl)cc1)c2=O Show InChI InChI=1S/C31H22ClF3N4O4S/c32-21-11-7-18(8-12-21)13-14-38-27(40)25-15-22(16-31(33,34)35)44-28(25)39(30(38)42)17-19-5-9-20(10-6-19)23-3-1-2-4-24(23)26-36-29(41)43-37-26/h1-12,15H,13-14,16-17H2,(H,36,37,41) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description
Binding assay using human AT1. |
US Patent US8501750 (2013)
BindingDB Entry DOI: 10.7270/Q2F76B5Q |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM99959
(US8501750, 129)Show SMILES COc1cc(F)ccc1C(=O)Cn1c(=O)n(Cc2ccc(cc2F)-c2ccccc2-c2nc(=O)o[nH]2)c2sc(cc2c1=O)C1CC1 Show InChI InChI=1S/C33H24F2N4O6S/c1-44-27-13-20(34)10-11-23(27)26(40)16-38-30(41)24-14-28(17-6-7-17)46-31(24)39(33(38)43)15-19-9-8-18(12-25(19)35)21-4-2-3-5-22(21)29-36-32(42)45-37-29/h2-5,8-14,17H,6-7,15-16H2,1H3,(H,36,37,42) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description
Binding assay using human AT1. |
US Patent US8501750 (2013)
BindingDB Entry DOI: 10.7270/Q2F76B5Q |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM99979
(US8501750, 180)Show SMILES CCc1cc2c(s1)n(Cc1ccc(cc1F)-c1ccccc1-c1nc(=O)o[nH]1)c(=O)n(-c1ccc(OC(C)C)cc1)c2=O Show InChI InChI=1S/C32H27FN4O5S/c1-4-23-16-26-29(38)37(21-11-13-22(14-12-21)41-18(2)3)32(40)36(30(26)43-23)17-20-10-9-19(15-27(20)33)24-7-5-6-8-25(24)28-34-31(39)42-35-28/h5-16,18H,4,17H2,1-3H3,(H,34,35,39) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description
Binding assay using human AT1. |
US Patent US8501750 (2013)
BindingDB Entry DOI: 10.7270/Q2F76B5Q |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM99995
(US8501750, 225)Show SMILES CCc1cc2c(s1)n(Cc1ccc(cc1)-c1ccccc1-c1noc(=O)[nH]1)c(=O)n(CC(C)(C)c1ccccc1)c2=O Show InChI InChI=1S/C33H30N4O4S/c1-4-24-18-27-29(38)37(20-33(2,3)23-10-6-5-7-11-23)32(40)36(30(27)42-24)19-21-14-16-22(17-15-21)25-12-8-9-13-26(25)28-34-31(39)41-35-28/h5-18H,4,19-20H2,1-3H3,(H,34,35,39) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description
Binding assay using human AT1. |
US Patent US8501750 (2013)
BindingDB Entry DOI: 10.7270/Q2F76B5Q |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM99968
(US8501750, 144)Show SMILES CCc1cc2c(s1)n(Cc1ccc(cc1)-c1ccccc1-c1nc(=O)o[nH]1)c(=O)n(CC1(C)COC1)c2=O Show InChI InChI=1S/C28H26N4O5S/c1-3-19-12-22-24(33)32(14-28(2)15-36-16-28)27(35)31(25(22)38-19)13-17-8-10-18(11-9-17)20-6-4-5-7-21(20)23-29-26(34)37-30-23/h4-12H,3,13-16H2,1-2H3,(H,29,30,34) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description
Binding assay using human AT1. |
US Patent US8501750 (2013)
BindingDB Entry DOI: 10.7270/Q2F76B5Q |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM99983
(US8501750, 194)Show SMILES CCc1cc2c(s1)n(Cc1ccc(cc1Br)-c1ccccc1-c1noc(O)n1)c(=O)n(CC(=O)c1ccc(OC)cc1)c2=O Show InChI InChI=1S/C32H25BrN4O6S/c1-3-22-15-25-29(39)36(17-27(38)18-10-12-21(42-2)13-11-18)32(41)37(30(25)44-22)16-20-9-8-19(14-26(20)33)23-6-4-5-7-24(23)28-34-31(40)43-35-28/h4-15H,3,16-17H2,1-2H3,(H,34,35,40)/p-1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description
Binding assay using human AT1. |
US Patent US8501750 (2013)
BindingDB Entry DOI: 10.7270/Q2F76B5Q |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM99978
(US8501750, 158)Show SMILES CCCc1cc2c(s1)n(Cc1ccc(cc1F)-c1ccccc1-c1nc(=O)o[nH]1)c(=O)n(CC(=O)c1ccc(OC)cc1)c2=O Show InChI InChI=1S/C33H27FN4O6S/c1-3-6-23-16-26-30(40)37(18-28(39)19-11-13-22(43-2)14-12-19)33(42)38(31(26)45-23)17-21-10-9-20(15-27(21)34)24-7-4-5-8-25(24)29-35-32(41)44-36-29/h4-5,7-16H,3,6,17-18H2,1-2H3,(H,35,36,41)/p-1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description
Binding assay using human AT1. |
US Patent US8501750 (2013)
BindingDB Entry DOI: 10.7270/Q2F76B5Q |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM99962
(US8501750, 132)Show SMILES CCc1cc2c(s1)n(Cc1ccc(cc1)-c1ccccc1-c1nc(=O)o[nH]1)c(=O)n(CC(=O)C13CC4CC(CC(C4)C1)C3)c2=O |TLB:36:37:41:35.40.34,40:35:42:41.39.38,40:39:42:35.36.34,THB:36:35:41:42.37.38| Show InChI InChI=1S/C35H34N4O5S/c1-2-25-14-28-31(41)38(19-29(40)35-15-21-11-22(16-35)13-23(12-21)17-35)34(43)39(32(28)45-25)18-20-7-9-24(10-8-20)26-5-3-4-6-27(26)30-36-33(42)44-37-30/h3-10,14,21-23H,2,11-13,15-19H2,1H3,(H,36,37,42) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description
Binding assay using human AT1. |
US Patent US8501750 (2013)
BindingDB Entry DOI: 10.7270/Q2F76B5Q |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM99957
(US8501750, 121)Show SMILES CCc1cc2c(s1)n(Cc1ccc(cc1)-c1ccccc1-c1nc(=O)o[nH]1)c(=O)n(CC(=O)c1ccc(Cl)cc1)c2=O Show InChI InChI=1S/C31H23ClN4O5S/c1-2-22-15-25-28(38)35(17-26(37)20-11-13-21(32)14-12-20)31(40)36(29(25)42-22)16-18-7-9-19(10-8-18)23-5-3-4-6-24(23)27-33-30(39)41-34-27/h3-15H,2,16-17H2,1H3,(H,33,34,39) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description
Binding assay using human AT1. |
US Patent US8501750 (2013)
BindingDB Entry DOI: 10.7270/Q2F76B5Q |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM99965
(US8501750, 140)Show SMILES CCc1cc2c(s1)n(Cc1ccc(cc1)-c1ccccc1-c1nc(=O)o[nH]1)c(=O)n(CC(=O)c1nc3ccccc3n1C)c2=O Show InChI InChI=1S/C33H26N6O5S/c1-3-21-16-24-30(41)38(18-27(40)29-34-25-10-6-7-11-26(25)37(29)2)33(43)39(31(24)45-21)17-19-12-14-20(15-13-19)22-8-4-5-9-23(22)28-35-32(42)44-36-28/h4-16H,3,17-18H2,1-2H3,(H,35,36,42) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description
Binding assay using human AT1. |
US Patent US8501750 (2013)
BindingDB Entry DOI: 10.7270/Q2F76B5Q |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM99969
(US8501750, 145)Show SMILES CCc1cc2c(s1)n(Cc1ccc(cc1)-c1ccccc1-c1nc(=O)o[nH]1)c(=O)n(CC1(O)CCOCC1)c2=O Show InChI InChI=1S/C29H28N4O6S/c1-2-20-15-23-25(34)33(17-29(37)11-13-38-14-12-29)28(36)32(26(23)40-20)16-18-7-9-19(10-8-18)21-5-3-4-6-22(21)24-30-27(35)39-31-24/h3-10,15,37H,2,11-14,16-17H2,1H3,(H,30,31,35) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description
Binding assay using human AT1. |
US Patent US8501750 (2013)
BindingDB Entry DOI: 10.7270/Q2F76B5Q |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM99971
(US8501750, 149)Show SMILES CCc1cc2c(s1)n(Cc1ccc(cc1)-c1ccccc1-c1nc(=O)o[nH]1)c(=O)n(CC(O)C(C)(C)C)c2=O Show InChI InChI=1S/C29H30N4O5S/c1-5-19-14-22-25(35)32(16-23(34)29(2,3)4)28(37)33(26(22)39-19)15-17-10-12-18(13-11-17)20-8-6-7-9-21(20)24-30-27(36)38-31-24/h6-14,23,34H,5,15-16H2,1-4H3,(H,30,31,36) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description
Binding assay using human AT1. |
US Patent US8501750 (2013)
BindingDB Entry DOI: 10.7270/Q2F76B5Q |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM99986
(US8501750, 203)Show SMILES CCc1cc2c(s1)n(Cc1ccc(cc1)-c1cc(F)ccc1-c1nc(=O)o[nH]1)c(=O)n(CC(=O)c1ccc(OC)cc1)c2=O Show InChI InChI=1S/C32H25FN4O6S/c1-3-23-15-26-29(39)36(17-27(38)20-8-11-22(42-2)12-9-20)32(41)37(30(26)44-23)16-18-4-6-19(7-5-18)25-14-21(33)10-13-24(25)28-34-31(40)43-35-28/h4-15H,3,16-17H2,1-2H3,(H,34,35,40) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description
Binding assay using human AT1. |
US Patent US8501750 (2013)
BindingDB Entry DOI: 10.7270/Q2F76B5Q |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM99956
(US8501750, 117)Show SMILES CCc1cc2c(s1)n(Cc1ccc(cc1F)-c1ccccc1-c1nc(=O)o[nH]1)c(=O)n(CCN1CCOCC1)c2=O Show InChI InChI=1S/C29H28FN5O5S/c1-2-20-16-23-26(36)34(10-9-33-11-13-39-14-12-33)29(38)35(27(23)41-20)17-19-8-7-18(15-24(19)30)21-5-3-4-6-22(21)25-31-28(37)40-32-25/h3-8,15-16H,2,9-14,17H2,1H3,(H,31,32,37) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description
Binding assay using human AT1. |
US Patent US8501750 (2013)
BindingDB Entry DOI: 10.7270/Q2F76B5Q |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM99955
(US8501750, 116)Show SMILES CCc1cc2c(s1)n(Cc1ccc(cc1C)-c1ccccc1-c1noc(O)n1)c(=O)n(CC(=O)c1ccc(OC)cc1)c2=O Show InChI InChI=1S/C33H28N4O6S/c1-4-24-16-27-30(39)36(18-28(38)20-11-13-23(42-3)14-12-20)33(41)37(31(27)44-24)17-22-10-9-21(15-19(22)2)25-7-5-6-8-26(25)29-34-32(40)43-35-29/h5-16H,4,17-18H2,1-3H3,(H,34,35,40)/p-1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description
Binding assay using human AT1. |
US Patent US8501750 (2013)
BindingDB Entry DOI: 10.7270/Q2F76B5Q |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM99991
(US8501750, 214)Show SMILES CCc1cc2c(s1)n(Cc1ccc(cc1)-c1ccccc1-c1nc(=O)o[nH]1)c(=O)n(CC(=NOCC=C)c1ccc(OC)cc1)c2=O Show InChI InChI=1S/C35H31N5O6S/c1-4-18-45-37-30(24-14-16-25(44-3)17-15-24)21-39-32(41)29-19-26(5-2)47-33(29)40(35(39)43)20-22-10-12-23(13-11-22)27-8-6-7-9-28(27)31-36-34(42)46-38-31/h4,6-17,19H,1,5,18,20-21H2,2-3H3,(H,36,38,42) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description
Binding assay using human AT1. |
US Patent US8501750 (2013)
BindingDB Entry DOI: 10.7270/Q2F76B5Q |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM99994
(US8501750, 222)Show SMILES CCc1cc2c(s1)n(Cc1ccc(cc1)-c1ccccc1-c1nc(=O)o[nH]1)c(=O)n(CC(=O)c1sccc1Br)c2=O Show InChI InChI=1S/C29H21BrN4O5S2/c1-2-18-13-21-26(36)33(15-23(35)24-22(30)11-12-40-24)29(38)34(27(21)41-18)14-16-7-9-17(10-8-16)19-5-3-4-6-20(19)25-31-28(37)39-32-25/h3-13H,2,14-15H2,1H3,(H,31,32,37) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description
Binding assay using human AT1. |
US Patent US8501750 (2013)
BindingDB Entry DOI: 10.7270/Q2F76B5Q |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM99976
(US8501750, 154)Show SMILES CCc1cc2c(s1)n(Cc1ccc(cc1OC)-c1ccccc1C#N)c(=O)[nH]c2=O Show InChI InChI=1S/C23H19N3O3S/c1-3-17-11-19-21(27)25-23(28)26(22(19)30-17)13-16-9-8-14(10-20(16)29-2)18-7-5-4-6-15(18)12-24/h4-11H,3,13H2,1-2H3,(H,25,27,28) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description
Binding assay using human AT1. |
US Patent US8501750 (2013)
BindingDB Entry DOI: 10.7270/Q2F76B5Q |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM99990
(US8501750, 213)Show SMILES CCc1cc2c(s1)n(Cc1ccc(cc1)-c1ccccc1-c1nc(=O)o[nH]1)c(=O)n(CC(=NOC(C)C)c1ccc(OC)cc1)c2=O Show InChI InChI=1S/C35H33N5O6S/c1-5-26-18-29-32(41)39(20-30(37-45-21(2)3)24-14-16-25(44-4)17-15-24)35(43)40(33(29)47-26)19-22-10-12-23(13-11-22)27-8-6-7-9-28(27)31-36-34(42)46-38-31/h6-18,21H,5,19-20H2,1-4H3,(H,36,38,42) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description
Binding assay using human AT1. |
US Patent US8501750 (2013)
BindingDB Entry DOI: 10.7270/Q2F76B5Q |
More data for this
Ligand-Target Pair | |
Type-1 angiotensin II receptor
(Homo sapiens (Human)) | BDBM99982
(US8501750, 192)Show SMILES CCc1cc2c(s1)n(Cc1ccc(cc1OC)-c1ccccc1-c1nc(=O)o[nH]1)c(=O)n(CC(=O)c1ccc(OC)cc1)c2=O Show InChI InChI=1S/C33H28N4O7S/c1-4-23-16-26-30(39)36(18-27(38)19-11-13-22(42-2)14-12-19)33(41)37(31(26)45-23)17-21-10-9-20(15-28(21)43-3)24-7-5-6-8-25(24)29-34-32(40)44-35-29/h5-16H,4,17-18H2,1-3H3,(H,34,35,40)/p-1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description
Binding assay using human AT1. |
US Patent US8501750 (2013)
BindingDB Entry DOI: 10.7270/Q2F76B5Q |
More data for this
Ligand-Target Pair | |
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