| Reaction Details |
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 | Report a problem with these data |
| Target | Type-1 angiotensin II receptor |
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| Ligand | BDBM99952 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Binding Assay |
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| IC50 | 1.0±0.0 nM |
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| Citation |  Kuroita, T; Igawa, H; Sakamoto, H; Asano, K; Sasaki, M Heterocyclic compound and use thereof US Patent US8501750 Publication Date 8/6/2013 |
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| More Info.: | Get all data from this article, Assay Method |
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| Type-1 angiotensin II receptor |
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| Name: | Type-1 angiotensin II receptor |
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| Synonyms: | AGTR1 | AGTR1A | AGTR1B | AGTR1_HUMAN | AT1 | AT1AR | AT1BR | AT2R1 | AT2R1B | Angiotensin II AT1 | Angiotensin II receptor | Angiotensin II type 1b (AT-1b) receptor | Type-1 angiotensin II receptor (AT1) |
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| Type: | Protein |
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| Mol. Mass.: | 41080.75 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P30556 |
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| Residue: | 359 |
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| Sequence: | MILNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLK
TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLT
CLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVC
AFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFK
IIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIRDCRIADIVDTAMPITICIAYFNNCLNPL
FYGFLGKKFKRYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSTKKPAPCFEVE
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| BDBM99952 |
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| n/a |
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| Name | BDBM99952 |
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| Synonyms: | US8501750, 105 |
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| Type | Small organic molecule |
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| Emp. Form. | C33H25FN4O6S |
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| Mol. Mass. | 624.638 |
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| SMILES | COc1ccc(cc1)C(=O)Cn1c(=O)n(Cc2ccc(cc2F)-c2ccccc2-c2noc(O)n2)c2sc(cc2c1=O)C1CC1 |
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| Structure | 
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