Affinity Data by Patent

Patent code US8778932

Found 5 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Gamma-aminobutyric acid receptor subunit alpha-5 (Homo sapiens (Human))	BDBM126721 (US8778932, 36) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Les Laboratoires Servier; Egis Gyogyszergyar Nyrt US Patent					Assay Description The compounds are tested on HEK-293 (Human Embryonic Kidney) cells stably expressing the subunit α5 of the human GABAA receptor, and also the su...				US Patent US8778932 (2014) BindingDB Entry DOI: 10.7270/Q2CR5S2X
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-5 (Homo sapiens (Human))	BDBM126717 (US8778932, 6) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Les Laboratoires Servier; Egis Gyogyszergyar Nyrt US Patent					Assay Description The compounds are tested on HEK-293 (Human Embryonic Kidney) cells stably expressing the subunit α5 of the human GABAA receptor, and also the su...				US Patent US8778932 (2014) BindingDB Entry DOI: 10.7270/Q2CR5S2X
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-5 (Homo sapiens (Human))	BDBM126719 (US8778932, 21) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	US Patent	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Les Laboratoires Servier; Egis Gyogyszergyar Nyrt US Patent					Assay Description The compounds are tested on HEK-293 (Human Embryonic Kidney) cells stably expressing the subunit α5 of the human GABAA receptor, and also the su...				US Patent US8778932 (2014) BindingDB Entry DOI: 10.7270/Q2CR5S2X
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-5 (Homo sapiens (Human))	BDBM126718 (US8778932, 9) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Les Laboratoires Servier; Egis Gyogyszergyar Nyrt US Patent					Assay Description The compounds are tested on HEK-293 (Human Embryonic Kidney) cells stably expressing the subunit α5 of the human GABAA receptor, and also the su...				US Patent US8778932 (2014) BindingDB Entry DOI: 10.7270/Q2CR5S2X
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-5 (Homo sapiens (Human))	BDBM126720 (US8778932, 31) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Les Laboratoires Servier; Egis Gyogyszergyar Nyrt US Patent					Assay Description The compounds are tested on HEK-293 (Human Embryonic Kidney) cells stably expressing the subunit α5 of the human GABAA receptor, and also the su...				US Patent US8778932 (2014) BindingDB Entry DOI: 10.7270/Q2CR5S2X
					More data for this Ligand-Target Pair

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* indicates data uncertainty>20%