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Patent code US10544141

Compile Data Set for Download or QSAR
Found 90 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein P


(HBV)		BDBM427487
PNG
(US10544141, Compound 546)
Show SMILES Clc1cccc(NC(=O)N2CCc3[nH]nc(c3C2)C23CC2CCC3)c1
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US Patent
n/an/an/an/a 55n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427494
PNG
(US10544141, Compound 861)
Show SMILES Clc1cccc(NC(=O)N2CCc3[nH]nc(C4CCCO4)c3C2)c1
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n/an/an/an/a 55n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427496
PNG
(US10544141, Compound 761)
Show SMILES CC1Cc2[nH]nc(C3CCC3)c2CN1C(=O)Nc1cccc(C#N)c1F
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US Patent
n/an/an/an/a 300n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427498
PNG
(US10544141, Compound 928)
Show SMILES CC1Cc2[nH]nc(C3CCCC3)c2CN1C(=O)Nc1ccc(F)c(Br)c1
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n/an/an/an/a 55n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427503
PNG
(US10544141, Compound 933)
Show SMILES CC1Cc2[nH]nc(C3CCCC3)c2CN1C(=O)Nc1cccc(C)c1
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US Patent
n/an/an/an/a 55n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427509
PNG
(US10544141, Compound 968)
Show SMILES CC1Cc2[nH]nc(C3CCCO3)c2CN1C(=O)Nc1ccnc(Br)c1F
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n/an/an/an/a 750n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427510
PNG
(US10544141, Compound 969)
Show SMILES CC1Cc2[nH]nc(C3CCCO3)c2CN1C(=O)Nc1ccc(F)c(c1)C#N
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n/an/an/an/a 300n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427539
PNG
(US10544141, Compound 791)
Show SMILES Fc1c(Br)nccc1NC(=O)N1CCc2[nH]nc(c2C1)C12CC1CCC2
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n/an/an/an/a 55n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427549
PNG
(US10544141, Compound 757)
Show SMILES CC1Cc2[nH]nc(C3CCC3)c2CN1C(=O)Nc1cccc(Br)c1
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n/an/an/an/a 55n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427562
PNG
(US10544141, Compound 668)
Show SMILES Fc1ccc(NC(=O)N2CCc3[nH]nc(C4CCC4)c3C2)cc1C#N
Show InChI InChI=1S/C18H18FN5O/c19-15-5-4-13(8-12(15)9-20)21-18(25)24-7-6-16-14(10-24)17(23-22-16)11-2-1-3-11/h4-5,8,11H,1-3,6-7,10H2,(H,21,25)(H,22,23)
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n/an/an/an/a 55n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427484
PNG
(US10544141, Compound 274)
Show SMILES Clc1cccc(NC(=O)N2CCc3[nH]nc(c3C2)C2=CCOCC2)c1 |t:20|
Show InChI InChI=1S/C18H19ClN4O2/c19-13-2-1-3-14(10-13)20-18(24)23-7-4-16-15(11-23)17(22-21-16)12-5-8-25-9-6-12/h1-3,5,10H,4,6-9,11H2,(H,20,24)(H,21,22)
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n/an/an/an/a 300n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427486
PNG
(US10544141, Compound 275)
Show SMILES Clc1cccc(NC(=O)N2CCc3[nH]nc(C4CCOCC4)c3C2)c1
Show InChI InChI=1S/C18H21ClN4O2/c19-13-2-1-3-14(10-13)20-18(24)23-7-4-16-15(11-23)17(22-21-16)12-5-8-25-9-6-12/h1-3,10,12H,4-9,11H2,(H,20,24)(H,21,22)
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n/an/an/an/a 300n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427492
PNG
(US10544141, Compound 338)
Show SMILES Clc1cccc(NC(=O)N2CCc3[nH]nc(C4=CCCC4)c3C2)c1 |t:16|
Show InChI InChI=1S/C18H19ClN4O/c19-13-6-3-7-14(10-13)20-18(24)23-9-8-16-15(11-23)17(22-21-16)12-4-1-2-5-12/h3-4,6-7,10H,1-2,5,8-9,11H2,(H,20,24)(H,21,22)
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n/an/an/an/a 55n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427496
PNG
(US10544141, Compound 761)
Show SMILES CC1Cc2[nH]nc(C3CCC3)c2CN1C(=O)Nc1cccc(C#N)c1F
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n/an/an/an/a 300n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427501
PNG
(US10544141, Compound 931)
Show SMILES CC1Cc2[nH]nc(C3CCCC3)c2CN1C(=O)Nc1ccc(F)c(C)c1
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n/an/an/an/a 55n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427502
PNG
(US10544141, Compound 932)
Show SMILES CC1Cc2[nH]nc(C3CCCC3)c2CN1C(=O)Nc1ccc(F)c(Cl)c1
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n/an/an/an/a 55n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427512
PNG
(US10544141, Compound 971)
Show SMILES CC1Cc2[nH]nc(C3CCCO3)c2CN1C(=O)Nc1ccc(F)c(C)c1
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n/an/an/an/a 55n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427516
PNG
(US10544141, Compound 388)
Show SMILES CC(CO)c1n[nH]c2CCN(Cc12)C(=O)Nc1cccc(Cl)c1
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n/an/an/an/a>1.00E+4n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427520
PNG
(US10544141, Compound 782)
Show SMILES Fc1c(Cl)nccc1NC(=O)N1CCc2[nH]nc(c2C1)C12CC1CCC2
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NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427534
PNG
(US10544141, Compound 661)
Show SMILES Cc1cccc(NC(=O)N2CCc3[nH]nc(C4CCC4)c3C2)c1
Show InChI InChI=1S/C18H22N4O/c1-12-4-2-7-14(10-12)19-18(23)22-9-8-16-15(11-22)17(21-20-16)13-5-3-6-13/h2,4,7,10,13H,3,5-6,8-9,11H2,1H3,(H,19,23)(H,20,21)
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n/an/an/an/a 300n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427535
PNG
(US10544141, Compound 789)
Show SMILES Fc1ccc(NC(=O)N2CCc3[nH]nc(c3C2)C23CC2CCC3)cc1Br
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n/an/an/an/a 55n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427537
PNG
(US10544141, Compound 790)
Show SMILES Fc1ccc(NC(=O)N2CCc3[nH]nc(c3C2)C23CC2CCC3)cc1C#N
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n/an/an/an/a 55n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427548
PNG
(US10544141, Compound 763)
Show SMILES CC1Cc2[nH]nc(C3CCC3)c2CN1C(=O)Nc1cccc(C)c1
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n/an/an/an/a 55n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427559
PNG
(US10544141, Compound 759)
Show SMILES CC1Cc2[nH]nc(C3CCC3)c2CN1C(=O)Nc1cccc(Br)c1F
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n/an/an/an/a 300n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427490
PNG
(US10544141, Compound 337)
Show SMILES Clc1cccc(NC(=O)N2CCc3[nH]nc(c3C2)C2=CCCCC2)c1 |t:20|
Show InChI InChI=1S/C19H21ClN4O/c20-14-7-4-8-15(11-14)21-19(25)24-10-9-17-16(12-24)18(23-22-17)13-5-2-1-3-6-13/h4-5,7-8,11H,1-3,6,9-10,12H2,(H,21,25)(H,22,23)
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n/an/an/an/a 55n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427499
PNG
(US10544141, Compound 929)
Show SMILES CC1Cc2[nH]nc(C3CCCC3)c2CN1C(=O)Nc1ccnc(Br)c1F
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n/an/an/an/a 55n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427500
PNG
(US10544141, Compound 930)
Show SMILES CC1Cc2[nH]nc(C3CCCC3)c2CN1C(=O)Nc1ccc(F)c(c1)C#N
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n/an/an/an/a 55n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427504
PNG
(US10544141, Compound 934)
Show SMILES CC1Cc2[nH]nc(C3CCCC3)c2CN1C(=O)Nc1cccc(Cl)c1
UniProtKB/SwissProt

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n/an/an/an/a 55n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427508
PNG
(US10544141, Compound 967)
Show SMILES CC1Cc2[nH]nc(C3CCCO3)c2CN1C(=O)Nc1ccc(F)c(Br)c1
UniProtKB/SwissProt

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n/an/an/an/a 55n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427508
PNG
(US10544141, Compound 967)
Show SMILES CC1Cc2[nH]nc(C3CCCO3)c2CN1C(=O)Nc1ccc(F)c(Br)c1
UniProtKB/SwissProt

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n/an/an/an/a 300n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427515
PNG
(US10544141, Compound 241)
Show SMILES Oc1n[nH]c2CCN(Cc12)C(=O)Nc1cccc(Cl)c1
Show InChI InChI=1S/C13H13ClN4O2/c14-8-2-1-3-9(6-8)15-13(20)18-5-4-11-10(7-18)12(19)17-16-11/h1-3,6H,4-5,7H2,(H,15,20)(H2,16,17,19)
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n/an/an/an/a>1.00E+4n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427518
PNG
(US10544141, Compound 669)
Show SMILES Fc1ccc(NC(=O)N2CCc3[nH]nc(C4CCC4)c3C2)cc1F
Show InChI InChI=1S/C17H18F2N4O/c18-13-5-4-11(8-14(13)19)20-17(24)23-7-6-15-12(9-23)16(22-21-15)10-2-1-3-10/h4-5,8,10H,1-3,6-7,9H2,(H,20,24)(H,21,22)
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n/an/an/an/a 300n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427522
PNG
(US10544141, Compound 783)
Show SMILES Cc1cccc(NC(=O)N2CCc3[nH]nc(c3C2)C23CC2CCC3)c1
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NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427530
PNG
(US10544141, Compound 700)
Show SMILES FC(F)(F)C1(CC1)c1n[nH]c2CCN(Cc12)C(=O)Nc1cccc(Cl)c1
Show InChI InChI=1S/C17H16ClF3N4O/c18-10-2-1-3-11(8-10)22-15(26)25-7-4-13-12(9-25)14(24-23-13)16(5-6-16)17(19,20)21/h1-3,8H,4-7,9H2,(H,22,26)(H,23,24)
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NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427536
PNG
(US10544141, Compound 662)
Show SMILES Fc1c(Br)cccc1NC(=O)N1CCc2[nH]nc(C3CCC3)c2C1
Show InChI InChI=1S/C17H18BrFN4O/c18-12-5-2-6-14(15(12)19)20-17(24)23-8-7-13-11(9-23)16(22-21-13)10-3-1-4-10/h2,5-6,10H,1,3-4,7-9H2,(H,20,24)(H,21,22)
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NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427540
PNG
(US10544141, Compound 664)
Show SMILES Fc1c(Br)nccc1NC(=O)N1CCc2[nH]nc(C3CCC3)c2C1
Show InChI InChI=1S/C16H17BrFN5O/c17-15-13(18)12(4-6-19-15)20-16(24)23-7-5-11-10(8-23)14(22-21-11)9-2-1-3-9/h4,6,9H,1-3,5,7-8H2,(H,21,22)(H,19,20,24)
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n/an/an/an/a 300n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427545
PNG
(US10544141, Compound 742)
Show SMILES OC1CCC(C1)c1n[nH]c2CCN(Cc12)C(=O)Nc1cccc(Cl)c1
UniProtKB/SwissProt

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n/an/an/an/a 300n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427557
PNG
(US10544141, Compound 758)
Show SMILES CC1Cc2[nH]nc(C3CCC3)c2CN1C(=O)Nc1ccc(F)c(Br)c1
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NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427204
PNG
(US10544141, Compound 264)
Show SMILES Clc1cccc(NC(=O)N2CCc3[nH]nc(C4CCCC4)c3C2)c1
Show InChI InChI=1S/C18H21ClN4O/c19-13-6-3-7-14(10-13)20-18(24)23-9-8-16-15(11-23)17(22-21-16)12-4-1-2-5-12/h3,6-7,10,12H,1-2,4-5,8-9,11H2,(H,20,24)(H,21,22)
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NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427240
PNG
(US10544141, Compound 267)
Show SMILES CC(C)c1n[nH]c2CCN(Cc12)C(=O)Nc1cccc(Cl)c1
Show InChI InChI=1S/C16H19ClN4O/c1-10(2)15-13-9-21(7-6-14(13)19-20-15)16(22)18-12-5-3-4-11(17)8-12/h3-5,8,10H,6-7,9H2,1-2H3,(H,18,22)(H,19,20)
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n/an/an/an/a 300n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427485
PNG
(US10544141, Compound 515)
Show SMILES CC(C)(C)c1n[nH]c2CCN(Cc12)C(=O)Nc1cccc(Cl)c1
Show InChI InChI=1S/C17H21ClN4O/c1-17(2,3)15-13-10-22(8-7-14(13)20-21-15)16(23)19-12-6-4-5-11(18)9-12/h4-6,9H,7-8,10H2,1-3H3,(H,19,23)(H,20,21)
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n/an/an/an/a 300n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427489
PNG
(US10544141, Compound 547)
Show SMILES CC(=C)c1n[nH]c2CCN(Cc12)C(=O)Nc1ccnc(Cl)c1F
Show InChI InChI=1S/C15H15ClFN5O/c1-8(2)13-9-7-22(6-4-10(9)20-21-13)15(23)19-11-3-5-18-14(16)12(11)17/h3,5H,1,4,6-7H2,2H3,(H,20,21)(H,18,19,23)
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n/an/an/an/a 300n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427495
PNG
(US10544141, Compound 554)
Show SMILES Clc1cccc(NC(=O)N2CCc3[nH]nc(C4CCC4)c3C2)c1
Show InChI InChI=1S/C17H19ClN4O/c18-12-5-2-6-13(9-12)19-17(23)22-8-7-15-14(10-22)16(21-20-15)11-3-1-4-11/h2,5-6,9,11H,1,3-4,7-8,10H2,(H,19,23)(H,20,21)
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n/an/an/an/a 55n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427497
PNG
(US10544141, Compound 927)
Show SMILES CC1Cc2[nH]nc(C3CCCC3)c2CN1C(=O)Nc1cccc(Br)c1
UniProtKB/SwissProt

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n/an/an/an/a 55n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427512
PNG
(US10544141, Compound 971)
Show SMILES CC1Cc2[nH]nc(C3CCCO3)c2CN1C(=O)Nc1ccc(F)c(C)c1
UniProtKB/SwissProt

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n/an/an/an/a 300n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427521
PNG
(US10544141, Compound 644)
Show SMILES CCCc1n[nH]c2CCN(Cc12)C(=O)Nc1cccc(Cl)c1
Show InChI InChI=1S/C16H19ClN4O/c1-2-4-14-13-10-21(8-7-15(13)20-19-14)16(22)18-12-6-3-5-11(17)9-12/h3,5-6,9H,2,4,7-8,10H2,1H3,(H,18,22)(H,19,20)
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NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427529
PNG
(US10544141, Compound 786)
Show SMILES Fc1c(NC(=O)N2CCc3[nH]nc(c3C2)C23CC2CCC3)cccc1C#N
UniProtKB/SwissProt

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NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427546
PNG
(US10544141, Compound 762)
Show SMILES CC1Cc2[nH]nc(C3CCC3)c2CN1C(=O)Nc1ccc(F)c(c1)C#N
UniProtKB/SwissProt

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n/an/an/an/a 55n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427550
PNG
(US10544141, Compound 764)
Show SMILES CC1Cc2[nH]nc(C3CCC3)c2CN1C(=O)Nc1ccc(F)c(C)c1
UniProtKB/SwissProt

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n/an/an/an/a 55n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427497
PNG
(US10544141, Compound 927)
Show SMILES CC1Cc2[nH]nc(C3CCCC3)c2CN1C(=O)Nc1cccc(Br)c1
UniProtKB/SwissProt

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NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427505
PNG
(US10544141, Compound 964)
Show SMILES CC1Cc2[nH]nc(C3CCCO3)c2CN1C(=O)Nc1cccc(Cl)c1
UniProtKB/SwissProt

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NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427510
PNG
(US10544141, Compound 969)
Show SMILES CC1Cc2[nH]nc(C3CCCO3)c2CN1C(=O)Nc1ccc(F)c(c1)C#N
UniProtKB/SwissProt

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n/an/an/an/a 300n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427527
PNG
(US10544141, Compound 785)
Show SMILES Brc1cccc(NC(=O)N2CCc3[nH]nc(c3C2)C23CC2CCC3)c1
UniProtKB/SwissProt

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NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427532
PNG
(US10544141, Compound 660)
Show SMILES Fc1c(Cl)nccc1NC(=O)N1CCc2[nH]nc(C3CCC3)c2C1
Show InChI InChI=1S/C16H17ClFN5O/c17-15-13(18)12(4-6-19-15)20-16(24)23-7-5-11-10(8-23)14(22-21-11)9-2-1-3-9/h4,6,9H,1-3,5,7-8H2,(H,21,22)(H,19,20,24)
UniProtKB/SwissProt

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n/an/an/an/a 300n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427547
PNG
(US10544141, Compound 744)
Show SMILES FC1CCC(=C1)c1n[nH]c2CCN(Cc12)C(=O)Nc1cccc(Cl)c1 |c:4|
UniProtKB/SwissProt

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n/an/an/an/a 55n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427491
PNG
(US10544141, Compound 548)
Show SMILES CC(=C)c1n[nH]c2CCN(Cc12)C(=O)Nc1cccc(Br)c1F
Show InChI InChI=1S/C16H16BrFN4O/c1-9(2)15-10-8-22(7-6-12(10)20-21-15)16(23)19-13-5-3-4-11(17)14(13)18/h3-5H,1,6-8H2,2H3,(H,19,23)(H,20,21)
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NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427493
PNG
(US10544141, Compound 549)
Show SMILES CC(=C)c1n[nH]c2CCN(Cc12)C(=O)Nc1cccc(C)c1
Show InChI InChI=1S/C17H20N4O/c1-11(2)16-14-10-21(8-7-15(14)19-20-16)17(22)18-13-6-4-5-12(3)9-13/h4-6,9H,1,7-8,10H2,2-3H3,(H,18,22)(H,19,20)
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n/an/an/an/a 300n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427511
PNG
(US10544141, Compound 970)
Show SMILES CC1Cc2[nH]nc(C3CCCO3)c2CN1C(=O)Nc1cccc(C)c1
UniProtKB/SwissProt

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NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427514
PNG
(US10544141, Compound 260)
Show SMILES Clc1cccc(NC(=O)N2CCc3[nH]nc(Br)c3C2)c1
Show InChI InChI=1S/C13H12BrClN4O/c14-12-10-7-19(5-4-11(10)17-18-12)13(20)16-9-3-1-2-8(15)6-9/h1-3,6H,4-5,7H2,(H,16,20)(H,17,18)
UniProtKB/SwissProt

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n/an/an/an/a>1.00E+4n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427517
PNG
(US10544141, Compound 604)
Show SMILES CCC(C)(C)c1n[nH]c2CCN(Cc12)C(=O)Nc1cccc(Cl)c1
Show InChI InChI=1S/C18H23ClN4O/c1-4-18(2,3)16-14-11-23(9-8-15(14)21-22-16)17(24)20-13-7-5-6-12(19)10-13/h5-7,10H,4,8-9,11H2,1-3H3,(H,20,24)(H,21,22)
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n/an/an/an/a 300n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427526
PNG
(US10544141, Compound 694)
Show SMILES CC1(CCC1)c1n[nH]c2CCN(Cc12)C(=O)Nc1cccc(Cl)c1
Show InChI InChI=1S/C18H21ClN4O/c1-18(7-3-8-18)16-14-11-23(9-6-15(14)21-22-16)17(24)20-13-5-2-4-12(19)10-13/h2,4-5,10H,3,6-9,11H2,1H3,(H,20,24)(H,21,22)
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n/an/an/an/a 55n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427533
PNG
(US10544141, Compound 788)
Show SMILES Cc1cc(NC(=O)N2CCc3[nH]nc(c3C2)C23CC2CCC3)ccc1F
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n/an/an/an/a 55n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427538
PNG
(US10544141, Compound 663)
Show SMILES Brc1cccc(NC(=O)N2CCc3[nH]nc(C4CCC4)c3C2)c1
Show InChI InChI=1S/C17H19BrN4O/c18-12-5-2-6-13(9-12)19-17(23)22-8-7-15-14(10-22)16(21-20-15)11-3-1-4-11/h2,5-6,9,11H,1,3-4,7-8,10H2,(H,19,23)(H,20,21)
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n/an/an/an/a 55n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427541
PNG
(US10544141, Compound 792)
Show SMILES Fc1ccc(NC(=O)N2CCc3[nH]nc(c3C2)C23CC2CCC3)cc1F
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n/an/an/an/a 300n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427542
PNG
(US10544141, Compound 665)
Show SMILES Fc1ccc(NC(=O)N2CCc3[nH]nc(C4CCC4)c3C2)cc1Cl
Show InChI InChI=1S/C17H18ClFN4O/c18-13-8-11(4-5-14(13)19)20-17(24)23-7-6-15-12(9-23)16(22-21-15)10-2-1-3-10/h4-5,8,10H,1-3,6-7,9H2,(H,20,24)(H,21,22)
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n/an/an/an/a 55n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427543
PNG
(US10544141, Compound 760)
Show SMILES CC1Cc2[nH]nc(C3CCC3)c2CN1C(=O)Nc1ccnc(Br)c1F
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n/an/an/an/a 300n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427560
PNG
(US10544141, Compound 667)
Show SMILES Fc1ccc(NC(=O)N2CCc3[nH]nc(C4CCC4)c3C2)cc1Br
Show InChI InChI=1S/C17H18BrFN4O/c18-13-8-11(4-5-14(13)19)20-17(24)23-7-6-15-12(9-23)16(22-21-15)10-2-1-3-10/h4-5,8,10H,1-3,6-7,9H2,(H,20,24)(H,21,22)
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n/an/an/an/a 55n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427223
PNG
(US10544141, Compound 441)
Show SMILES CC1(CC1)c1n[nH]c2CCN(Cc12)C(=O)Nc1cccc(Cl)c1
Show InChI InChI=1S/C17H19ClN4O/c1-17(6-7-17)15-13-10-22(8-5-14(13)20-21-15)16(23)19-12-4-2-3-11(18)9-12/h2-4,9H,5-8,10H2,1H3,(H,19,23)(H,20,21)
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n/an/an/an/a 300n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427499
PNG
(US10544141, Compound 929)
Show SMILES CC1Cc2[nH]nc(C3CCCC3)c2CN1C(=O)Nc1ccnc(Br)c1F
UniProtKB/SwissProt

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n/an/an/an/a 55n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427502
PNG
(US10544141, Compound 932)
Show SMILES CC1Cc2[nH]nc(C3CCCC3)c2CN1C(=O)Nc1ccc(F)c(Cl)c1
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n/an/an/an/a 55n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427503
PNG
(US10544141, Compound 933)
Show SMILES CC1Cc2[nH]nc(C3CCCC3)c2CN1C(=O)Nc1cccc(C)c1
UniProtKB/SwissProt

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n/an/an/an/a 55n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427506
PNG
(US10544141, Compound 965)
Show SMILES CC1Cc2[nH]nc(C3CCCO3)c2CN1C(=O)Nc1ccc(F)c(Cl)c1
UniProtKB/SwissProt

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n/an/an/an/a 55n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427506
PNG
(US10544141, Compound 965)
Show SMILES CC1Cc2[nH]nc(C3CCCO3)c2CN1C(=O)Nc1ccc(F)c(Cl)c1
UniProtKB/SwissProt

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n/an/an/an/a 55n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427513
PNG
(US10544141, Compound 238)
Show SMILES CC(C)(O)c1n[nH]c2CCN(Cc12)C(=O)Nc1cccc(Cl)c1
Show InChI InChI=1S/C16H19ClN4O2/c1-16(2,23)14-12-9-21(7-6-13(12)19-20-14)15(22)18-11-5-3-4-10(17)8-11/h3-5,8,23H,6-7,9H2,1-2H3,(H,18,22)(H,19,20)
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n/an/an/an/a>1.00E+4n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427523
PNG
(US10544141, Compound 693)
Show SMILES Clc1cccc(NC(=O)N2CCc3[nH]nc(C4CC=CC4)c3C2)c1 |c:18|
Show InChI InChI=1S/C18H19ClN4O/c19-13-6-3-7-14(10-13)20-18(24)23-9-8-16-15(11-23)17(22-21-16)12-4-1-2-5-12/h1-3,6-7,10,12H,4-5,8-9,11H2,(H,20,24)(H,21,22)
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n/an/an/an/a 55n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427531
PNG
(US10544141, Compound 787)
Show SMILES Fc1ccc(NC(=O)N2CCc3[nH]nc(c3C2)C23CC2CCC3)cc1Cl
UniProtKB/SwissProt

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n/an/an/an/a 55n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427558
PNG
(US10544141, Compound 765)
Show SMILES CC1Cc2[nH]nc(C3CCC3)c2CN1C(=O)Nc1ccc(F)c(F)c1
UniProtKB/SwissProt

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n/an/an/an/a 55n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427466
PNG
(US10544141, Compound 455)
Show SMILES Clc1cccc(NC(=O)N2CCc3[nH]nc(N4CCCC4)c3C2)c1
Show InChI InChI=1S/C17H20ClN5O/c18-12-4-3-5-13(10-12)19-17(24)23-9-6-15-14(11-23)16(21-20-15)22-7-1-2-8-22/h3-5,10H,1-2,6-9,11H2,(H,19,24)(H,20,21)
UniProtKB/SwissProt

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n/an/an/an/a 300n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427488
PNG
(US10544141, Compound 336)
Show SMILES CC(=C)c1n[nH]c2CCN(Cc12)C(=O)Nc1cccc(Cl)c1
Show InChI InChI=1S/C16H17ClN4O/c1-10(2)15-13-9-21(7-6-14(13)19-20-15)16(22)18-12-5-3-4-11(17)8-12/h3-5,8H,1,6-7,9H2,2H3,(H,18,22)(H,19,20)
UniProtKB/SwissProt

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n/an/an/an/a 55n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427498
PNG
(US10544141, Compound 928)
Show SMILES CC1Cc2[nH]nc(C3CCCC3)c2CN1C(=O)Nc1ccc(F)c(Br)c1
UniProtKB/SwissProt

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n/an/an/an/a 55n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427500
PNG
(US10544141, Compound 930)
Show SMILES CC1Cc2[nH]nc(C3CCCC3)c2CN1C(=O)Nc1ccc(F)c(c1)C#N
UniProtKB/SwissProt

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n/an/an/an/a 55n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427501
PNG
(US10544141, Compound 931)
Show SMILES CC1Cc2[nH]nc(C3CCCC3)c2CN1C(=O)Nc1ccc(F)c(C)c1
UniProtKB/SwissProt

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n/an/an/an/a 55n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427504
PNG
(US10544141, Compound 934)
Show SMILES CC1Cc2[nH]nc(C3CCCC3)c2CN1C(=O)Nc1cccc(Cl)c1
UniProtKB/SwissProt

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n/an/an/an/a 55n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427507
PNG
(US10544141, Compound 966)
Show SMILES CC1Cc2[nH]nc(C3CCCO3)c2CN1C(=O)Nc1cccc(Br)c1
UniProtKB/SwissProt

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NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427519
PNG
(US10544141, Compound 642)
Show SMILES CCCC(F)(F)c1n[nH]c2CCN(Cc12)C(=O)Nc1cccc(Cl)c1
Show InChI InChI=1S/C17H19ClF2N4O/c1-2-7-17(19,20)15-13-10-24(8-6-14(13)22-23-15)16(25)21-12-5-3-4-11(18)9-12/h3-5,9H,2,6-8,10H2,1H3,(H,21,25)(H,22,23)
UniProtKB/SwissProt

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n/an/an/an/a 55n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427525
PNG
(US10544141, Compound 784)
Show SMILES Fc1c(Br)cccc1NC(=O)N1CCc2[nH]nc(c2C1)C12CC1CCC2
UniProtKB/SwissProt

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NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427528
PNG
(US10544141, Compound 696)
Show SMILES CCC(F)(F)c1n[nH]c2CCN(Cc12)C(=O)Nc1cccc(Cl)c1
Show InChI InChI=1S/C16H17ClF2N4O/c1-2-16(18,19)14-12-9-23(7-6-13(12)21-22-14)15(24)20-11-5-3-4-10(17)8-11/h3-5,8H,2,6-7,9H2,1H3,(H,20,24)(H,21,22)
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n/an/an/an/a 300n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427543
PNG
(US10544141, Compound 760)
Show SMILES CC1Cc2[nH]nc(C3CCC3)c2CN1C(=O)Nc1ccnc(Br)c1F
UniProtKB/SwissProt

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n/an/an/an/a 300n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427544
PNG
(US10544141, Compound 440)
Show SMILES Clc1cccc(NC(=O)N2CCc3[nH]nc(C4CC4)c3C2)c1
Show InChI InChI=1S/C16H17ClN4O/c17-11-2-1-3-12(8-11)18-16(22)21-7-6-14-13(9-21)15(20-19-14)10-4-5-10/h1-3,8,10H,4-7,9H2,(H,18,22)(H,19,20)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 300n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
Protein P


(HBV)		BDBM427561
PNG
(US10544141, Compound 666)
Show SMILES Cc1cc(NC(=O)N2CCc3[nH]nc(C4CCC4)c3C2)ccc1F
Show InChI InChI=1S/C18H21FN4O/c1-11-9-13(5-6-15(11)19)20-18(24)23-8-7-16-14(10-23)17(22-21-16)12-3-2-4-12/h5-6,9,12H,2-4,7-8,10H2,1H3,(H,20,24)(H,21,22)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 55n/an/an/an/a



NOVIRA THERAPEUTICS, INC.

US Patent


Assay Description
HBV replication inhibition by the compounds of this invention could be determined in cells infected or transfected with HBV, or cells with stably int...

US Patent US10544141 (2020)


BindingDB Entry DOI: 10.7270/Q2V69MZV
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%