| Reaction Details |
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 | Report a problem with these data |
| Target | Protein P |
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| Ligand | BDBM427525 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | HBV Replication Inhibition Assay |
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| EC50 | 55±n/a nM |
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| Citation |  Hartman, GD; Kuduk, S Derivatives and methods of treating hepatitis B infections US Patent US10544141 Publication Date 1/28/2020 |
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| More Info.: | Get all data from this article, Assay Method |
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| Protein P |
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| Name: | Protein P |
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| Synonyms: | P | Q9WRL0_HBV | polymerase |
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| Type: | Protein |
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| Mol. Mass.: | 94822.25 |
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| Organism: | HBV |
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| Description: | Q9WRL0 |
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| Residue: | 845 |
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| Sequence: | MPLSYQHFRKLLLLDDGTEAGPLEEELPRLADADLNRRVAEDLNLGNPNVSIPWTHKVGN
FTGLYSSTVPIFNPEWQTPSFPKIHLQEDIINRCEQFVGPLTVNEKRRLKLIMPARFYPT
HTKYLPLDKGIKPYYPDQVVNHYFQTRHYLHTLWKAGILYKRETTRSASFCGSPYSWEQE
LQHGRLVIKTSQRHGDESFCSQPSGILSRSSVGPCIRSQLKQSRLGLQPHQGPLASSQPG
RSGSIRARVHPSTRRCFGVEPSGSGHVDPSVNNSSSCLRQSAVRKAAHSHLSTSKRQSSS
GDAVEFHCLPPSSARPQSQGSVFSCWWLQFRNSKPCSEYCLSHIVNLREDWGPCDEHGEH
HIRIPRTPARVTGGVFLVDKNPHNTEESRLVVDFSQFSRGITRVSWPKFAVPNLQSLTNL
LSSNLSWLSLDVSAAFYHIPLHPAAMPHLLIGSSGLSRYVARLSSNSRINNNQYGTMQNL
HDSCSRQLYVSLMLLYKTYGWKLHLYSHPIVLGFRKIPMGVGLSPFLLAQFTSAICSVVR
RAFPHCLAFSYMDDVVLGAKTVQHRESLYTAVTNFLLSLGIHLNPNKTKRWGYSLNFMGY
VIGSWGTLPQDHIVQKIKHCFRKLPVNRPIDWKVCQRIVGLLGFAAPFTQCGYPALMPLY
ACIQAKQAFTFSPTYKAFLSKQYMNLYPVARQRPGLCQVFADATPTGWGLAIGHQRMRGT
FVAPLPIHTAELLAACFARSRSGAKLIGTDNSVVLSRKYTSFPWLLGCAANWILRGTSFV
YVPSALNPADDPSRGRLGLSRPLLRLPFQPTTGRTSLYAVSPSVPSHLPVRVHFASPLHV
AWRPP
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| BDBM427525 |
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| n/a |
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| Name | BDBM427525 |
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| Synonyms: | US10544141, Compound 784 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H20BrFN4O |
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| Mol. Mass. | 419.291 |
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| SMILES | Fc1c(Br)cccc1NC(=O)N1CCc2[nH]nc(c2C1)C12CC1CCC2 |
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| Structure | 
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