Affinity Data by Patent

Patent code US9676712

Found 15 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM179834 (US9676712, 2C) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.10	n/a	5.70	n/a	n/a	n/a	n/a	6.0	n/a
CAYMAN CHEMICAL COMPANY, INC. US Patent					Assay Description 200 μl in 96-well plate. Cell membrane homogenates (20 μg protein) are incubated for 120 min at 22� C. with 0.5 nM [3H]PGE2 in the absence ...				US Patent US9676712 (2017) BindingDB Entry DOI: 10.7270/Q23X84T9
CAYMAN CHEMICAL COMPANY, INC. US Patent					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM179827 (US9676712, 1C) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.80	n/a	10	n/a	n/a	n/a	n/a	6.0	n/a
CAYMAN CHEMICAL COMPANY, INC. US Patent					Assay Description 200 μl in 96-well plate. Cell membrane homogenates (20 μg protein) are incubated for 120 min at 22� C. with 0.5 nM [3H]PGE2 in the absence ...				US Patent US9676712 (2017) BindingDB Entry DOI: 10.7270/Q23X84T9
CAYMAN CHEMICAL COMPANY, INC. US Patent					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM179827 (US9676712, 1C) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.0140	n/a	n/a	n/a	n/a
CAYMAN CHEMICAL COMPANY, INC. US Patent					Assay Description 1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 μl of reduced serum medium containing 0.5% FBS. Place ...				US Patent US9676712 (2017) BindingDB Entry DOI: 10.7270/Q23X84T9
CAYMAN CHEMICAL COMPANY, INC. US Patent					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM179834 (US9676712, 2C) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.00700	n/a	n/a	n/a	25
CAYMAN CHEMICAL COMPANY, INC. US Patent					Assay Description 1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 μL of reduced serum medium containing 0.5% FBE. Place ...				US Patent US9676712 (2017) BindingDB Entry DOI: 10.7270/Q23X84T9
CAYMAN CHEMICAL COMPANY, INC. US Patent					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM179986 (US9676712, 3C) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
CAYMAN CHEMICAL COMPANY, INC. US Patent					Assay Description 1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 μl of reduced serum medium containing 0.5% FBS. Place ...				US Patent US9676712 (2017) BindingDB Entry DOI: 10.7270/Q23X84T9
CAYMAN CHEMICAL COMPANY, INC. US Patent					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM179985 (US9676712, 3D) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	32	n/a	n/a	n/a	n/a
CAYMAN CHEMICAL COMPANY, INC. US Patent					Assay Description 1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 μl of reduced serum medium containing 0.5% FBS. Place ...				US Patent US9676712 (2017) BindingDB Entry DOI: 10.7270/Q23X84T9
CAYMAN CHEMICAL COMPANY, INC. US Patent					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM179834 (US9676712, 2C) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
CAYMAN CHEMICAL COMPANY, INC. US Patent					Assay Description 1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 μl of reduced serum medium containing 0.5% FBS. Place ...				US Patent US9676712 (2017) BindingDB Entry DOI: 10.7270/Q23X84T9
CAYMAN CHEMICAL COMPANY, INC. US Patent					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM179985 (US9676712, 3D) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
CAYMAN CHEMICAL COMPANY, INC. US Patent					Assay Description 1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 μl of reduced serum medium containing 0.5% FBS. Place ...				US Patent US9676712 (2017) BindingDB Entry DOI: 10.7270/Q23X84T9
CAYMAN CHEMICAL COMPANY, INC. US Patent					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM179991 (US9676712, 4C) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.00300	n/a	n/a	n/a	n/a
CAYMAN CHEMICAL COMPANY, INC. US Patent					Assay Description 1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 μl of reduced serum medium containing 0.5% FBS. Place ...				US Patent US9676712 (2017) BindingDB Entry DOI: 10.7270/Q23X84T9
CAYMAN CHEMICAL COMPANY, INC. US Patent					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM179827 (US9676712, 1C) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.37	n/a	n/a	n/a	25
CAYMAN CHEMICAL COMPANY, INC. US Patent					Assay Description 1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 μL of reduced serum medium containing 0.5% FBE. Place ...				US Patent US9676712 (2017) BindingDB Entry DOI: 10.7270/Q23X84T9
CAYMAN CHEMICAL COMPANY, INC. US Patent					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM179827 (US9676712, 1C) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
CAYMAN CHEMICAL COMPANY, INC. US Patent					Assay Description 1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 μl of reduced serum medium containing 0.5% FBS. Place ...				US Patent US9676712 (2017) BindingDB Entry DOI: 10.7270/Q23X84T9
CAYMAN CHEMICAL COMPANY, INC. US Patent					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM179834 (US9676712, 2C) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.00100	n/a	n/a	n/a	n/a
CAYMAN CHEMICAL COMPANY, INC. US Patent					Assay Description 1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 μl of reduced serum medium containing 0.5% FBS. Place ...				US Patent US9676712 (2017) BindingDB Entry DOI: 10.7270/Q23X84T9
CAYMAN CHEMICAL COMPANY, INC. US Patent					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM179987 (US9676712, 4D) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
CAYMAN CHEMICAL COMPANY, INC. US Patent					Assay Description 1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 μl of reduced serum medium containing 0.5% FBS. Place ...				US Patent US9676712 (2017) BindingDB Entry DOI: 10.7270/Q23X84T9
CAYMAN CHEMICAL COMPANY, INC. US Patent					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM179986 (US9676712, 3C) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.0190	n/a	n/a	n/a	n/a
CAYMAN CHEMICAL COMPANY, INC. US Patent					Assay Description 1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 μl of reduced serum medium containing 0.5% FBS. Place ...				US Patent US9676712 (2017) BindingDB Entry DOI: 10.7270/Q23X84T9
CAYMAN CHEMICAL COMPANY, INC. US Patent					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM179991 (US9676712, 4C) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.28E+3	n/a	n/a	n/a	n/a
CAYMAN CHEMICAL COMPANY, INC. US Patent					Assay Description 1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 μl of reduced serum medium containing 0.5% FBS. Place ...				US Patent US9676712 (2017) BindingDB Entry DOI: 10.7270/Q23X84T9
CAYMAN CHEMICAL COMPANY, INC. US Patent					More data for this Ligand-Target Pair

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* indicates data uncertainty>20%