Affinity Data by Patent

Patent code US8802721

Found 9 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Interleukin-2 (Homo sapiens (Human))	BDBM128384 (US8802721, 1) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Synta Pharmaceuticals Corp. US Patent					Assay Description Jurkat cells were placed in a 96 well plate (0.5 million cells per well in 1% FBS medium) then a test compound of this invention was added at differe...				US Patent US8802721 (2014) BindingDB Entry DOI: 10.7270/Q2CN72M4
Synta Pharmaceuticals Corp. US Patent					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM128386 (US8802721, 3) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.40	n/a	n/a	n/a	n/a	n/a	n/a
Synta Pharmaceuticals Corp. US Patent					Assay Description Jurkat cells were placed in a 96 well plate (0.5 million cells per well in 1% FBS medium) then a test compound of this invention was added at differe...				US Patent US8802721 (2014) BindingDB Entry DOI: 10.7270/Q2CN72M4
Synta Pharmaceuticals Corp. US Patent					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM128385 (US8802721, 2) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Synta Pharmaceuticals Corp. US Patent					Assay Description Jurkat cells were placed in a 96 well plate (0.5 million cells per well in 1% FBS medium) then a test compound of this invention was added at differe...				US Patent US8802721 (2014) BindingDB Entry DOI: 10.7270/Q2CN72M4
Synta Pharmaceuticals Corp. US Patent					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM128388 (US8802721, 117) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16.5	n/a	n/a	n/a	n/a	n/a	n/a
Synta Pharmaceuticals Corp. US Patent					Assay Description Jurkat cells were placed in a 96 well plate (0.5 million cells per well in 1% FBS medium) then a test compound of this invention was added at differe...				US Patent US8802721 (2014) BindingDB Entry DOI: 10.7270/Q2CN72M4
Synta Pharmaceuticals Corp. US Patent					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM128387 (US8802721, 4) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	58.5	n/a	n/a	n/a	n/a	n/a	n/a
Synta Pharmaceuticals Corp. US Patent					Assay Description Jurkat cells were placed in a 96 well plate (0.5 million cells per well in 1% FBS medium) then a test compound of this invention was added at differe...				US Patent US8802721 (2014) BindingDB Entry DOI: 10.7270/Q2CN72M4
Synta Pharmaceuticals Corp. US Patent					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM128391 (US8802721, 120) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	87	n/a	n/a	n/a	n/a	n/a	n/a
Synta Pharmaceuticals Corp. US Patent					Assay Description Jurkat cells were placed in a 96 well plate (0.5 million cells per well in 1% FBS medium) then a test compound of this invention was added at differe...				US Patent US8802721 (2014) BindingDB Entry DOI: 10.7270/Q2CN72M4
Synta Pharmaceuticals Corp. US Patent					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM128390 (US8802721, 119) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	94.8	n/a	n/a	n/a	n/a	n/a	n/a
Synta Pharmaceuticals Corp. US Patent					Assay Description Jurkat cells were placed in a 96 well plate (0.5 million cells per well in 1% FBS medium) then a test compound of this invention was added at differe...				US Patent US8802721 (2014) BindingDB Entry DOI: 10.7270/Q2CN72M4
Synta Pharmaceuticals Corp. US Patent					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM128389 (US8802721, 118) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	104	n/a	n/a	n/a	n/a	n/a	n/a
Synta Pharmaceuticals Corp. US Patent					Assay Description Jurkat cells were placed in a 96 well plate (0.5 million cells per well in 1% FBS medium) then a test compound of this invention was added at differe...				US Patent US8802721 (2014) BindingDB Entry DOI: 10.7270/Q2CN72M4
Synta Pharmaceuticals Corp. US Patent					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM128392 (US8802721, 121) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	164	n/a	n/a	n/a	n/a	n/a	n/a
Synta Pharmaceuticals Corp. US Patent					Assay Description Jurkat cells were placed in a 96 well plate (0.5 million cells per well in 1% FBS medium) then a test compound of this invention was added at differe...				US Patent US8802721 (2014) BindingDB Entry DOI: 10.7270/Q2CN72M4
Synta Pharmaceuticals Corp. US Patent					More data for this Ligand-Target Pair

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* indicates data uncertainty>20%