Affinity Data by Patent

Patent code US8921421

Found 2 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 (Homo sapiens (Human))	BDBM141899 (US8921421, L-257 \| hDDAH inhibitor, 2a) Show SMILES COCCNC(=N)NCCC[C@H](N)C(O)=O \|r\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem Similars	PDB US Patent	1.30E+4	n/a	2.90E+4	n/a	n/a	n/a	n/a	7.4	n/a
Christian-Albrechts-Universitaet Zu Kiel US Patent					Assay Description This assay was used to determine the inhibiting effect of the inhibitors in a concentration of 1 mM. A standard incubation mixture consisted of 75 &#...				US Patent US8921421 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GP9
Christian-Albrechts-Universitaet Zu Kiel US Patent					More data for this Ligand-Target Pair				3D Structure (crystal)
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 (Homo sapiens (Human))	BDBM141900 (US8921421, 3) Show SMILES COCCNC(=N)NCCCCN Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	1.80E+4	n/a	7.00E+4	n/a	n/a	n/a	n/a	7.4	n/a
Christian-Albrechts-Universitaet Zu Kiel US Patent					Assay Description This assay was used to determine the inhibiting effect of the inhibitors in a concentration of 1 mM. A standard incubation mixture consisted of 75 &#...				US Patent US8921421 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GP9
Christian-Albrechts-Universitaet Zu Kiel US Patent					More data for this Ligand-Target Pair

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Change energy units to:kcal/mole

* indicates data uncertainty>20%