Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'N(G),N(G)-dimethylarginine dimethylaminohydrolase 1' and Ligand = 'BDBM141899'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 (Homo sapiens (Human))	BDBM141899 (US8921421, L-257 | hDDAH inhibitor, 2a) Show SMILES COCCNC(=N)NCCC[C@H](N)C(O)=O |r| Show InChI InChI=1S/C9H20N4O3/c1-16-6-5-13-9(11)12-4-2-3-7(10)8(14)15/h7H,2-6,10H2,1H3,(H,14,15)(H3,11,12,13)/t7-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem Similars	PDB US Patent	1.30E+4	n/a	2.90E+4	n/a	n/a	n/a	n/a	7.4	n/a
Christian-Albrechts-Universitaet Zu Kiel US Patent					Assay Description This assay was used to determine the inhibiting effect of the inhibitors in a concentration of 1 mM. A standard incubation mixture consisted of 75 &#...				US Patent US8921421 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GP9
					More data for this Ligand-Target Pair				3D Structure (crystal)
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 (Homo sapiens (Human))	BDBM141899 (US8921421, L-257 | hDDAH inhibitor, 2a) Show SMILES COCCNC(=N)NCCC[C@H](N)C(O)=O |r| Show InChI InChI=1S/C9H20N4O3/c1-16-6-5-13-9(11)12-4-2-3-7(10)8(14)15/h7H,2-6,10H2,1H3,(H,14,15)(H3,11,12,13)/t7-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem Similars	PDB Article PubMed	1.30E+4	-29.0	n/a	n/a	n/a	n/a	n/a	7.4	37
Christian-Albrechts-University					Assay Description A colorimetric assay was carried out in 150 μL 50 mM potassium phosphate buffer pH 7.4 containing 4 μg of recombinant hDDAH-1 and varying c...				J Enzyme Inhib Med Chem 27: 24-8 (2012) Article DOI: 10.3109/14756366.2011.573480 BindingDB Entry DOI: 10.7270/Q24B3064
					More data for this Ligand-Target Pair				3D Structure (crystal)