Affinity Data by Patent

Patent code US9289400

Found 6 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM218671 (US9289400, ES609) Show SMILES CC(N)CCc1ccccc1Cl Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	293	n/a	n/a	n/a	n/a	n/a	n/a
Drexel University; Rutgers, The State University of New Jersey US Patent					Assay Description Functional efficacy was determined by assessing the ability of PBZI and ES609 to inhibit monoamine transporter uptake activity.				US Patent US9289400 (2016) BindingDB Entry DOI: 10.7270/Q29S1PWN
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM218672 (US9289400, PBZI) Show SMILES CCCN1CCC2C1CCc1ccc(O)cc21 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	860	n/a	n/a	n/a	n/a	n/a	n/a
Drexel University; Rutgers, The State University of New Jersey US Patent					Assay Description Functional efficacy was determined by assessing the ability of PBZI and ES609 to inhibit monoamine transporter uptake activity.				US Patent US9289400 (2016) BindingDB Entry DOI: 10.7270/Q29S1PWN
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM218672 (US9289400, PBZI) Show SMILES CCCN1CCC2C1CCc1ccc(O)cc21 Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	1.61E+3	n/a	n/a	n/a	n/a	n/a	n/a
Drexel University; Rutgers, The State University of New Jersey US Patent					Assay Description Functional efficacy was determined by assessing the ability of PBZI and ES609 to inhibit monoamine transporter uptake activity.				US Patent US9289400 (2016) BindingDB Entry DOI: 10.7270/Q29S1PWN
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM218671 (US9289400, ES609) Show SMILES CC(N)CCc1ccccc1Cl Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	8.52E+3	n/a	n/a	n/a	n/a	n/a	n/a
Drexel University; Rutgers, The State University of New Jersey US Patent					Assay Description Functional efficacy was determined by assessing the ability of PBZI and ES609 to inhibit monoamine transporter uptake activity.				US Patent US9289400 (2016) BindingDB Entry DOI: 10.7270/Q29S1PWN
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM218672 (US9289400, PBZI) Show SMILES CCCN1CCC2C1CCc1ccc(O)cc21 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	1.38E+4	n/a	n/a	n/a	n/a	n/a	n/a
Drexel University; Rutgers, The State University of New Jersey US Patent					Assay Description Functional efficacy was determined by assessing the ability of PBZI and ES609 to inhibit monoamine transporter uptake activity.				US Patent US9289400 (2016) BindingDB Entry DOI: 10.7270/Q29S1PWN
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM218671 (US9289400, ES609) Show SMILES CC(N)CCc1ccccc1Cl Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	3.59E+4	n/a	n/a	n/a	n/a	n/a	n/a
Drexel University; Rutgers, The State University of New Jersey US Patent					Assay Description Functional efficacy was determined by assessing the ability of PBZI and ES609 to inhibit monoamine transporter uptake activity.				US Patent US9289400 (2016) BindingDB Entry DOI: 10.7270/Q29S1PWN
					More data for this Ligand-Target Pair

Reorder this table by EC50
Reorder this table by IC50
Reorder this table by Kd
Reorder this table by KON
Reorder this table by KOFF
Reorder this table by pH
Reorder this table by T
Reorder this table by ΔH°
Reorder this table by -TΔS°
Change energy units to:kcal/mole

* indicates data uncertainty>20%