BindingDB logo
myBDB logout

Patent code US9211296

Compile Data Set for Download or QSAR
Found 35 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
DNA polymerase


(Vaccinia virus (strain WR))		BDBM196131
PNG
(US9211296, Table 7, Compd: 1)
Show SMILES CCN1CCN(CC1)c1ccc(Nc2ccnc3cc4ccccc4cc23)cc1
Show InChI InChI=1S/C25H26N4/c1-2-28-13-15-29(16-14-28)22-9-7-21(8-10-22)27-24-11-12-26-25-18-20-6-4-3-5-19(20)17-23(24)25/h3-12,17-18H,2,13-16H2,1H3,(H,26,27)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

MCE
PC cid
PC sid
UniChem
US Patent
n/an/a 500n/an/an/an/a7.437



The Trustees of the University of Pennsylvania

US Patent


Assay Description
A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...

US Patent US9211296 (2015)


BindingDB Entry DOI: 10.7270/Q2G73CHS
More data for this
Ligand-Target Pair
DNA polymerase


(Vaccinia virus (strain WR))		BDBM196132
PNG
(US9211296, Table 7, Compd: 2)
Show SMILES BrCc1ccc(cc1)-c1noc(n1)-c1ccncc1
Show InChI InChI=1S/C14H10BrN3O/c15-9-10-1-3-11(4-2-10)13-17-14(19-18-13)12-5-7-16-8-6-12/h1-8H,9H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.30E+3n/an/an/an/a7.437



The Trustees of the University of Pennsylvania

US Patent


Assay Description
A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...

US Patent US9211296 (2015)


BindingDB Entry DOI: 10.7270/Q2G73CHS
More data for this
Ligand-Target Pair
DNA polymerase


(Vaccinia virus (strain WR))		BDBM196133
PNG
(US9211296, Table 7, Compd: 3)
Show SMILES CN(C)c1ccc(cc1)-c1cccc([o+]1)-c1ccc(cc1)N(C)C
Show InChI InChI=1S/C21H23N2O/c1-22(2)18-12-8-16(9-13-18)20-6-5-7-21(24-20)17-10-14-19(15-11-17)23(3)4/h5-15H,1-4H3/q+1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
US Patent
n/an/a 3.00E+3n/an/an/an/a7.437



The Trustees of the University of Pennsylvania

US Patent


Assay Description
A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...

US Patent US9211296 (2015)


BindingDB Entry DOI: 10.7270/Q2G73CHS
More data for this
Ligand-Target Pair
DNA polymerase


(Vaccinia virus (strain WR))		BDBM196134
PNG
(US9211296, Table 7, Compd: 4)
Show SMILES CC[n+]1cc(\C=C2/SC=CN2C)c(C)c2cc(OC)c3ccccc3c12 |c:8|
Show InChI InChI=1S/C22H23N2OS/c1-5-24-14-16(12-21-23(3)10-11-26-21)15(2)19-13-20(25-4)17-8-6-7-9-18(17)22(19)24/h6-14H,5H2,1-4H3/q+1/b21-12-
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3.50E+3n/an/an/an/a7.437



The Trustees of the University of Pennsylvania

US Patent


Assay Description
A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...

US Patent US9211296 (2015)


BindingDB Entry DOI: 10.7270/Q2G73CHS
More data for this
Ligand-Target Pair
DNA polymerase


(Vaccinia virus (strain WR))		BDBM196135
PNG
(US9211296, Table 7, Compd: 5)
Show SMILES CCOC(=O)CCc1c(CC(=O)OCC)cnc1\C=N\O
Show InChI InChI=1S/C14H19N2O5/c1-3-20-13(17)6-5-11-10(7-14(18)21-4-2)8-15-12(11)9-16-19/h8-9,19H,3-7H2,1-2H3/b16-9+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
KEGG
PC cid
PC sid
UniChem
US Patent
n/an/a 3.80E+3n/an/an/an/a7.437



The Trustees of the University of Pennsylvania

US Patent


Assay Description
A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...

US Patent US9211296 (2015)


BindingDB Entry DOI: 10.7270/Q2G73CHS
More data for this
Ligand-Target Pair
DNA polymerase


(Vaccinia virus (strain WR))		BDBM196136
PNG
(US9211296, Table 7, Compd: 6)
Show SMILES COc1ccc2N(C)\C(=C\c3sc4ccccc4[n+]3C)C=Cc2c1 |c:22|
Show InChI InChI=1S/C20H19N2OS/c1-21-15(9-8-14-12-16(23-3)10-11-17(14)21)13-20-22(2)18-6-4-5-7-19(18)24-20/h4-13H,1-3H3/q+1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 4.00E+3n/an/an/an/a7.437



The Trustees of the University of Pennsylvania

US Patent


Assay Description
A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...

US Patent US9211296 (2015)


BindingDB Entry DOI: 10.7270/Q2G73CHS
More data for this
Ligand-Target Pair
DNA polymerase


(Vaccinia virus (strain WR))		BDBM51365
PNG
(1-N-benzo[g]quinolin-4-yl-4-N-propan-2-ylbenzene-1...)
Show SMILES CC(C)Nc1ccc(Nc2ccnc3cc4ccccc4cc23)cc1
Show InChI InChI=1S/C22H21N3/c1-15(2)24-18-7-9-19(10-8-18)25-21-11-12-23-22-14-17-6-4-3-5-16(17)13-20(21)22/h3-15,24H,1-2H3,(H,23,25)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
US Patent
n/an/a 4.10E+3n/an/an/an/a7.437



The Trustees of the University of Pennsylvania

US Patent


Assay Description
A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...

US Patent US9211296 (2015)


BindingDB Entry DOI: 10.7270/Q2G73CHS
More data for this
Ligand-Target Pair
DNA polymerase


(Vaccinia virus (strain WR))		BDBM196137
PNG
(US9211296, Table 7, Compd: 8)
Show SMILES CCOC(=O)c1cnc2c(C)c(C)ccc2c1NCCCN(C)C
Show InChI InChI=1S/C19H27N3O2/c1-6-24-19(23)16-12-21-17-14(3)13(2)8-9-15(17)18(16)20-10-7-11-22(4)5/h8-9,12H,6-7,10-11H2,1-5H3,(H,20,21)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
US Patent
n/an/a 5.00E+3n/an/an/an/a7.437



The Trustees of the University of Pennsylvania

US Patent


Assay Description
A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...

US Patent US9211296 (2015)


BindingDB Entry DOI: 10.7270/Q2G73CHS
More data for this
Ligand-Target Pair
DNA polymerase


(Vaccinia virus (strain WR))		BDBM196138
PNG
(US9211296, Table 7, Compd: 9)
Show SMILES CC1=CC(C)(C)N=C(Nc2nc(C)c3cc(C)cc(C)c3n2)N1 |t:1,6|
Show InChI InChI=1S/C18H23N5/c1-10-7-11(2)15-14(8-10)13(4)20-16(21-15)22-17-19-12(3)9-18(5,6)23-17/h7-9H,1-6H3,(H2,19,20,21,22,23)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
US Patent
n/an/a 5.30E+3n/an/an/an/a7.437



The Trustees of the University of Pennsylvania

US Patent


Assay Description
A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...

US Patent US9211296 (2015)


BindingDB Entry DOI: 10.7270/Q2G73CHS
More data for this
Ligand-Target Pair
DNA polymerase


(Vaccinia virus (strain WR))		BDBM69679
PNG
(Dimethyl-(2-phenanthro[3,4-d][1,3]dioxol-5-yl-ethy...)
Show SMILES CN(C)CCc1cc2OCOc2c2c1ccc1ccccc21
Show InChI InChI=1S/C19H19NO2/c1-20(2)10-9-14-11-17-19(22-12-21-17)18-15-6-4-3-5-13(15)7-8-16(14)18/h3-8,11H,9-10,12H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.40E+3n/an/an/an/a7.437



The Trustees of the University of Pennsylvania

US Patent


Assay Description
A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...

US Patent US9211296 (2015)


BindingDB Entry DOI: 10.7270/Q2G73CHS
More data for this
Ligand-Target Pair
DNA polymerase


(Vaccinia virus (strain WR))		BDBM51312
PNG
(3-[(8,9-dimethoxy-2-phenyl-[1,2,4]triazolo[1,5-c]q...)
Show SMILES CCN(CC)CCCNc1nc2cc(OC)c(OC)cc2c2nc(nn12)-c1ccccc1
Show InChI InChI=1S/C24H30N6O2/c1-5-29(6-2)14-10-13-25-24-26-19-16-21(32-4)20(31-3)15-18(19)23-27-22(28-30(23)24)17-11-8-7-9-12-17/h7-9,11-12,15-16H,5-6,10,13-14H2,1-4H3,(H,25,26)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Similars
US Patent
n/an/a 5.90E+3n/an/an/an/a7.437



The Trustees of the University of Pennsylvania

US Patent


Assay Description
A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...

US Patent US9211296 (2015)


BindingDB Entry DOI: 10.7270/Q2G73CHS
More data for this
Ligand-Target Pair
DNA polymerase


(Vaccinia virus (strain WR))		BDBM196139
PNG
(US9211296, Table 7, Compd: 12)
Show SMILES Cc1cc(NCCN2CCCCC2)c2ccc3ccccc3c2n1
Show InChI InChI=1S/C21H25N3/c1-16-15-20(22-11-14-24-12-5-2-6-13-24)19-10-9-17-7-3-4-8-18(17)21(19)23-16/h3-4,7-10,15H,2,5-6,11-14H2,1H3,(H,22,23)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
US Patent
n/an/a 6.00E+3n/an/an/an/a7.437



The Trustees of the University of Pennsylvania

US Patent


Assay Description
A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...

US Patent US9211296 (2015)


BindingDB Entry DOI: 10.7270/Q2G73CHS
More data for this
Ligand-Target Pair
DNA polymerase


(Vaccinia virus (strain WR))		BDBM196140
PNG
(US9211296, Table 7, Compd: 13)
Show SMILES OC(CN1CCNCC1)Cn1c2ccc(Br)cc2c2cc(Br)ccc12
Show InChI InChI=1S/C19H21Br2N3O/c20-13-1-3-18-16(9-13)17-10-14(21)2-4-19(17)24(18)12-15(25)11-23-7-5-22-6-8-23/h1-4,9-10,15,22,25H,5-8,11-12H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

MCE
PC cid
PC sid
UniChem
US Patent
n/an/a 6.30E+3n/an/an/an/a7.437



The Trustees of the University of Pennsylvania

US Patent


Assay Description
A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...

US Patent US9211296 (2015)


BindingDB Entry DOI: 10.7270/Q2G73CHS
More data for this
Ligand-Target Pair
DNA polymerase


(Vaccinia virus (strain WR))		BDBM196141
PNG
(US9211296, Table 7, Compd: 14)
Show SMILES CN(C)CC\N=c1/cc(oc2ccc(Cl)cc12)-c1ccccc1
Show InChI InChI=1S/C19H19ClN2O/c1-22(2)11-10-21-17-13-19(14-6-4-3-5-7-14)23-18-9-8-15(20)12-16(17)18/h3-9,12-13H,10-11H2,1-2H3/b21-17+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 6.70E+3n/an/an/an/a7.437



The Trustees of the University of Pennsylvania

US Patent


Assay Description
A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...

US Patent US9211296 (2015)


BindingDB Entry DOI: 10.7270/Q2G73CHS
More data for this
Ligand-Target Pair
DNA polymerase


(Vaccinia virus (strain WR))		BDBM196142
PNG
(US9211296, Table 7, Compd: 15)
Show SMILES CC1CCCC(C)N1CCNc1nc2ccccc2c2nc(nn12)-c1ccccc1
Show InChI InChI=1S/C24H28N6/c1-17-9-8-10-18(2)29(17)16-15-25-24-26-21-14-7-6-13-20(21)23-27-22(28-30(23)24)19-11-4-3-5-12-19/h3-7,11-14,17-18H,8-10,15-16H2,1-2H3,(H,25,26)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
US Patent
n/an/a 7.30E+3n/an/an/an/a7.437



The Trustees of the University of Pennsylvania

US Patent


Assay Description
A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...

US Patent US9211296 (2015)


BindingDB Entry DOI: 10.7270/Q2G73CHS
More data for this
Ligand-Target Pair
DNA polymerase


(Vaccinia virus (strain WR))		BDBM196144
PNG
(US9211296, Table 7, Compd: 17)
Show SMILES COc1ccc2nc(NC(N)=N)nc(C)c2c1
Show InChI InChI=1S/C11H13N5O/c1-6-8-5-7(17-2)3-4-9(8)15-11(14-6)16-10(12)13/h3-5H,1-2H3,(H4,12,13,14,15,16)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
US Patent
n/an/a 7.40E+3n/an/an/an/a7.437



The Trustees of the University of Pennsylvania

US Patent


Assay Description
A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...

US Patent US9211296 (2015)


BindingDB Entry DOI: 10.7270/Q2G73CHS
More data for this
Ligand-Target Pair
DNA polymerase


(Vaccinia virus (strain WR))		BDBM196143
PNG
(US9211296, Table 7, Compd: 16)
Show SMILES OC(=O)c1ccc(CS(=O)(=O)c2ccccc2)o1
Show InChI InChI=1S/C12H10O5S/c13-12(14)11-7-6-9(17-11)8-18(15,16)10-4-2-1-3-5-10/h1-7H,8H2,(H,13,14)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

MCE
PC cid
PC sid
UniChem
US Patent
n/an/a 7.40E+3n/an/an/an/a7.437



The Trustees of the University of Pennsylvania

US Patent


Assay Description
A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...

US Patent US9211296 (2015)


BindingDB Entry DOI: 10.7270/Q2G73CHS
More data for this
Ligand-Target Pair
DNA polymerase


(Vaccinia virus (strain WR))		BDBM196146
PNG
(US9211296, Table 7, Compd: 19)
Show SMILES CN(C)CCN(Cc1ccco1)C(=O)c1cc2c(Cl)nc3ccc(C)cc3c2s1
Show InChI InChI=1S/C22H22ClN3O2S/c1-14-6-7-18-16(11-14)20-17(21(23)24-18)12-19(29-20)22(27)26(9-8-25(2)3)13-15-5-4-10-28-15/h4-7,10-12H,8-9,13H2,1-3H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
US Patent
n/an/a 1.00E+4n/an/an/an/a7.437



The Trustees of the University of Pennsylvania

US Patent


Assay Description
A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...

US Patent US9211296 (2015)


BindingDB Entry DOI: 10.7270/Q2G73CHS
More data for this
Ligand-Target Pair
DNA polymerase


(Vaccinia virus (strain WR))		BDBM196145
PNG
(US9211296, Table 7, Compd: 18)
Show SMILES Clc1nc2ccccc2c2sc(cc12)C(=O)NCCCN1CCCC1
Show InChI InChI=1S/C19H20ClN3OS/c20-18-14-12-16(19(24)21-8-5-11-23-9-3-4-10-23)25-17(14)13-6-1-2-7-15(13)22-18/h1-2,6-7,12H,3-5,8-11H2,(H,21,24)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
US Patent
n/an/a 1.00E+4n/an/an/an/a7.437



The Trustees of the University of Pennsylvania

US Patent


Assay Description
A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...

US Patent US9211296 (2015)


BindingDB Entry DOI: 10.7270/Q2G73CHS
More data for this
Ligand-Target Pair
DNA polymerase


(Vaccinia virus (strain WR))		BDBM196150
PNG
(US9211296, Table 6, 4)
Show SMILES Cc1csc2c(ncnc12)N1CCN(CC1)C(=O)NC(C)(C)C
Show InChI InChI=1S/C16H23N5OS/c1-11-9-23-13-12(11)17-10-18-14(13)20-5-7-21(8-6-20)15(22)19-16(2,3)4/h9-10H,5-8H2,1-4H3,(H,19,22)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
US Patent
n/an/a 1.20E+4n/an/an/an/a7.437



The Trustees of the University of Pennsylvania

US Patent


Assay Description
A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...

US Patent US9211296 (2015)


BindingDB Entry DOI: 10.7270/Q2G73CHS
More data for this
Ligand-Target Pair
DNA polymerase


(Vaccinia virus (strain WR))		BDBM196155
PNG
(US9211296, Table 6, 9)
Show SMILES OC(=O)c1ccccc1NC(=O)OCC1c2ccccc2-c2ccccc12
Show InChI InChI=1S/C22H17NO4/c24-21(25)18-11-5-6-12-20(18)23-22(26)27-13-19-16-9-3-1-7-14(16)15-8-2-4-10-17(15)19/h1-12,19H,13H2,(H,23,26)(H,24,25)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

MCE
PC cid
PC sid
UniChem
US Patent
n/an/a 2.60E+4n/an/an/an/a7.437



The Trustees of the University of Pennsylvania

US Patent


Assay Description
A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...

US Patent US9211296 (2015)


BindingDB Entry DOI: 10.7270/Q2G73CHS
More data for this
Ligand-Target Pair
DNA polymerase


(Vaccinia virus (strain WR))		BDBM196153
PNG
(US9211296, Table 6, 7)
Show SMILES Cc1c(cccc1C(O)=O)\N=C\c1cc(Br)cc(Br)c1Br
Show InChI InChI=1S/C15H10Br3NO2/c1-8-11(15(20)21)3-2-4-13(8)19-7-9-5-10(16)6-12(17)14(9)18/h2-7H,1H3,(H,20,21)/b19-7+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.60E+4n/an/an/an/a7.437



The Trustees of the University of Pennsylvania

US Patent


Assay Description
A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...

US Patent US9211296 (2015)


BindingDB Entry DOI: 10.7270/Q2G73CHS
More data for this
Ligand-Target Pair
DNA polymerase


(Vaccinia virus (strain WR))		BDBM196152
PNG
(US9211296, Table 6, 6)
Show SMILES Cc1cc(\N=C\c2cc(Cl)cc(Cl)c2O)no1
Show InChI InChI=1S/C11H8Cl2N2O2/c1-6-2-10(15-17-6)14-5-7-3-8(12)4-9(13)11(7)16/h2-5,16H,1H3/b14-5+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
US Patent
n/an/a 3.00E+4n/an/an/an/a7.437



The Trustees of the University of Pennsylvania

US Patent


Assay Description
A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...

US Patent US9211296 (2015)


BindingDB Entry DOI: 10.7270/Q2G73CHS
More data for this
Ligand-Target Pair
DNA polymerase


(Vaccinia virus (strain WR))		BDBM196158
PNG
(US9211296, Table 6, 12)
Show SMILES N=C1S\C(=C\c2ccco2)C(=O)N1c1nccs1
Show InChI InChI=1S/C11H7N3O2S2/c12-10-14(11-13-3-5-17-11)9(15)8(18-10)6-7-2-1-4-16-7/h1-6,12H/b8-6+,12-10?
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
US Patent
n/an/a 3.20E+4n/an/an/an/a7.437



The Trustees of the University of Pennsylvania

US Patent


Assay Description
A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...

US Patent US9211296 (2015)


BindingDB Entry DOI: 10.7270/Q2G73CHS
More data for this
Ligand-Target Pair
DNA polymerase


(Vaccinia virus (strain WR))		BDBM196157
PNG
(US9211296, Table 6, 11 | US9233921, 1)
Show SMILES Cc1ccc2c(Sc3ccc(Cl)cc3)c([nH]c2c1)C(O)=O
Show InChI InChI=1S/C16H12ClNO2S/c1-9-2-7-12-13(8-9)18-14(16(19)20)15(12)21-11-5-3-10(17)4-6-11/h2-8,18H,1H3,(H,19,20)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
US Patent
n/an/a 4.30E+4n/an/an/an/a7.437



The Trustees of the University of Pennsylvania

US Patent


Assay Description
A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...

US Patent US9211296 (2015)


BindingDB Entry DOI: 10.7270/Q2G73CHS
More data for this
Ligand-Target Pair
DNA polymerase


(Vaccinia virus (strain WR))		BDBM196159
PNG
(US9211296, Table 6, 13)
Show SMILES OC(=O)Cn1c2ccc(Cl)cc2c2nc3ccccc3nc12
Show InChI InChI=1S/C16H10ClN3O2/c17-9-5-6-13-10(7-9)15-16(20(13)8-14(21)22)19-12-4-2-1-3-11(12)18-15/h1-7H,8H2,(H,21,22)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
US Patent
n/an/a 4.60E+4n/an/an/an/a7.437



The Trustees of the University of Pennsylvania

US Patent


Assay Description
A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...

US Patent US9211296 (2015)


BindingDB Entry DOI: 10.7270/Q2G73CHS
More data for this
Ligand-Target Pair
DNA polymerase


(Vaccinia virus (strain WR))		BDBM196154
PNG
(US9211296, Table 6, 8)
Show SMILES Cc1cc(OC(=O)c2ccco2)nc(SCc2c(Cl)cccc2Cl)n1
Show InChI InChI=1S/C17H12Cl2N2O3S/c1-10-8-15(24-16(22)14-6-3-7-23-14)21-17(20-10)25-9-11-12(18)4-2-5-13(11)19/h2-8H,9H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
US Patent
n/an/a 5.20E+4n/an/an/an/a7.437



The Trustees of the University of Pennsylvania

US Patent


Assay Description
A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...

US Patent US9211296 (2015)


BindingDB Entry DOI: 10.7270/Q2G73CHS
More data for this
Ligand-Target Pair
DNA polymerase


(Vaccinia virus (strain WR))		BDBM196160
PNG
(US9211296, Table 6, 14)
Show SMILES N=C1N2N=CSC2=NC(=O)\C1=C/c1coc2ccccc2c1=O |c:3,7|
Show InChI InChI=1S/C15H8N4O3S/c16-13-10(14(21)18-15-19(13)17-7-23-15)5-8-6-22-11-4-2-1-3-9(11)12(8)20/h1-7,16H/b10-5-,16-13?
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
US Patent
n/an/a 7.50E+4n/an/an/an/a7.437



The Trustees of the University of Pennsylvania

US Patent


Assay Description
A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...

US Patent US9211296 (2015)


BindingDB Entry DOI: 10.7270/Q2G73CHS
More data for this
Ligand-Target Pair
DNA polymerase


(Vaccinia virus (strain WR))		BDBM196147
PNG
(US9211296, Table 6, 1)
Show SMILES COC(=O)c1cccc2\C(=N\O)c3ccccc3-c12
Show InChI InChI=1S/C15H11NO3/c1-19-15(17)12-8-4-7-11-13(12)9-5-2-3-6-10(9)14(11)16-18/h2-8,18H,1H3/b16-14+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
US Patent
n/an/a 1.08E+5n/an/an/an/a7.437



The Trustees of the University of Pennsylvania

US Patent


Assay Description
A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...

US Patent US9211296 (2015)


BindingDB Entry DOI: 10.7270/Q2G73CHS
More data for this
Ligand-Target Pair
DNA polymerase


(Vaccinia virus (strain WR))		BDBM196161
PNG
(US9211296, Table 6, 15)
Show SMILES CC(=O)n1c2ccccc2c2nc(C)sc12
Show InChI InChI=1S/C12H10N2OS/c1-7-13-11-9-5-3-4-6-10(9)14(8(2)15)12(11)16-7/h3-6H,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.11E+5n/an/an/an/a7.437



The Trustees of the University of Pennsylvania

US Patent


Assay Description
A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...

US Patent US9211296 (2015)


BindingDB Entry DOI: 10.7270/Q2G73CHS
More data for this
Ligand-Target Pair
DNA polymerase


(Vaccinia virus (strain WR))		BDBM196151
PNG
(US9211296, Table 6, 5)
Show SMILES CCNc1nc(SCc2ccc(Cl)cc2)nc2sc3CN(C)CCc3c12
Show InChI InChI=1S/C19H21ClN4S2/c1-3-21-17-16-14-8-9-24(2)10-15(14)26-18(16)23-19(22-17)25-11-12-4-6-13(20)7-5-12/h4-7H,3,8-11H2,1-2H3,(H,21,22,23)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
US Patent
n/an/a 1.29E+5n/an/an/an/a7.437



The Trustees of the University of Pennsylvania

US Patent


Assay Description
A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...

US Patent US9211296 (2015)


BindingDB Entry DOI: 10.7270/Q2G73CHS
More data for this
Ligand-Target Pair
DNA polymerase


(Vaccinia virus (strain WR))		BDBM196149
PNG
(US9211296, Table 6, 3)
Show SMILES CCn1c2ccccc2c2ccc(\C=N\n3cnnc3)cc12
Show InChI InChI=1S/C17H15N5/c1-2-22-16-6-4-3-5-14(16)15-8-7-13(9-17(15)22)10-20-21-11-18-19-12-21/h3-12H,2H2,1H3/b20-10+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.31E+5n/an/an/an/a7.437



The Trustees of the University of Pennsylvania

US Patent


Assay Description
A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...

US Patent US9211296 (2015)


BindingDB Entry DOI: 10.7270/Q2G73CHS
More data for this
Ligand-Target Pair
DNA polymerase


(Vaccinia virus (strain WR))		BDBM196156
PNG
(US9211296, Table 6, 10)
Show SMILES CCS(=O)(=O)N1CCN=C1SCc1ccc(Cl)cc1Cl |c:8|
Show InChI InChI=1S/C12H14Cl2N2O2S2/c1-2-20(17,18)16-6-5-15-12(16)19-8-9-3-4-10(13)7-11(9)14/h3-4,7H,2,5-6,8H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
US Patent
n/an/a 1.88E+5n/an/an/an/a7.437



The Trustees of the University of Pennsylvania

US Patent


Assay Description
A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...

US Patent US9211296 (2015)


BindingDB Entry DOI: 10.7270/Q2G73CHS
More data for this
Ligand-Target Pair
DNA polymerase


(Vaccinia virus (strain WR))		BDBM196162
PNG
(US9211296, Table 6, 16)
Show SMILES O=C1\C(CC\C1=C/C1CCCO1)=C\C1CCCO1
Show InChI InChI=1S/C15H20O3/c16-15-11(9-13-3-1-7-17-13)5-6-12(15)10-14-4-2-8-18-14/h9-10,13-14H,1-8H2/b11-9+,12-10+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
US Patent
n/an/a 2.39E+5n/an/an/an/a7.437



The Trustees of the University of Pennsylvania

US Patent


Assay Description
A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...

US Patent US9211296 (2015)


BindingDB Entry DOI: 10.7270/Q2G73CHS
More data for this
Ligand-Target Pair
DNA polymerase


(Vaccinia virus (strain WR))		BDBM196148
PNG
(US9211296, Table 6, 2)
Show SMILES CCOC(=O)c1c(NC(=O)\C=C\C(O)=O)sc(C)c1-c1ccccc1
Show InChI InChI=1S/C18H17NO5S/c1-3-24-18(23)16-15(12-7-5-4-6-8-12)11(2)25-17(16)19-13(20)9-10-14(21)22/h4-10H,3H2,1-2H3,(H,19,20)(H,21,22)/b10-9+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
US Patent
n/an/a 3.74E+5n/an/an/an/a7.437



The Trustees of the University of Pennsylvania

US Patent


Assay Description
A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...

US Patent US9211296 (2015)


BindingDB Entry DOI: 10.7270/Q2G73CHS
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%