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BDBM196146 US9211296, Table 7, Compd: 19

SMILES: CN(C)CCN(Cc1ccco1)C(=O)c1cc2c(Cl)nc3ccc(C)cc3c2s1

InChI Key: InChIKey=GZVKFJBGMUZJMD-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 196146   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
DNA Synthesis


(Vaccinia virus (strain WR))
BDBM196146
PNG
(US9211296, Table 7, Compd: 19)
Show SMILES CN(C)CCN(Cc1ccco1)C(=O)c1cc2c(Cl)nc3ccc(C)cc3c2s1
Show InChI InChI=1S/C22H22ClN3O2S/c1-14-6-7-18-16(11-14)20-17(21(23)24-18)12-19(29-20)22(27)26(9-8-25(2)3)13-15-5-4-10-28-15/h4-7,10-12H,8-9,13H2,1-3H3
PDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 1.00E+4n/an/an/an/a7.437



The Trustees of the University of Pennsylvania

US Patent


Assay Description
A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...


US Patent US9211296 (2015)


BindingDB Entry DOI: 10.7270/Q2G73CHS
More data for this
Ligand-Target Pair