Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Eukaryotic translation initiation factor 2-alpha kinase 3 (Homo sapiens (Human)) | BDBM227457 (US9333205, 61) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 240 | n/a | n/a | n/a | n/a | 7.5 | 25 |
NERVIANO MEDICAL SCIENCES S.R.L. US Patent | Assay Description The inhibitory activity of putative kinase inhibitors and the potency of selected compounds were determined using a trans-phosphorylation assay. Spec... | US Patent US9333205 (2016) BindingDB Entry DOI: 10.7270/Q22F7M9V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein kinase TTK (Homo sapiens (Human)) | BDBM227457 (US9333205, 61) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 360 | n/a | n/a | n/a | n/a | 7.5 | 25 |
NERVIANO MEDICAL SCIENCES S.R.L. US Patent | Assay Description The inhibitory activity of putative kinase inhibitors and the potency of selected compounds were determined using a trans-phosphorylation assay. Spec... | US Patent US9333205 (2016) BindingDB Entry DOI: 10.7270/Q22F7M9V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Eukaryotic translation initiation factor 2-alpha kinase 3 (Homo sapiens (Human)) | BDBM227455 (US9333205, 30) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 400 | n/a | n/a | n/a | n/a | 7.5 | 25 |
NERVIANO MEDICAL SCIENCES S.R.L. US Patent | Assay Description The inhibitory activity of putative kinase inhibitors and the potency of selected compounds were determined using a trans-phosphorylation assay. Spec... | US Patent US9333205 (2016) BindingDB Entry DOI: 10.7270/Q22F7M9V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Eukaryotic translation initiation factor 2-alpha kinase 3 (Homo sapiens (Human)) | BDBM227456 (US9333205, 55) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 510 | n/a | n/a | n/a | n/a | 7.5 | 25 |
NERVIANO MEDICAL SCIENCES S.R.L. US Patent | Assay Description The inhibitory activity of putative kinase inhibitors and the potency of selected compounds were determined using a trans-phosphorylation assay. Spec... | US Patent US9333205 (2016) BindingDB Entry DOI: 10.7270/Q22F7M9V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein kinase TTK (Homo sapiens (Human)) | BDBM227455 (US9333205, 30) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 680 | n/a | n/a | n/a | n/a | 7.5 | 25 |
NERVIANO MEDICAL SCIENCES S.R.L. US Patent | Assay Description The inhibitory activity of putative kinase inhibitors and the potency of selected compounds were determined using a trans-phosphorylation assay. Spec... | US Patent US9333205 (2016) BindingDB Entry DOI: 10.7270/Q22F7M9V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein kinase TTK (Homo sapiens (Human)) | BDBM227456 (US9333205, 55) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.44E+3 | n/a | n/a | n/a | n/a | 7.5 | 25 |
NERVIANO MEDICAL SCIENCES S.R.L. US Patent | Assay Description The inhibitory activity of putative kinase inhibitors and the potency of selected compounds were determined using a trans-phosphorylation assay. Spec... | US Patent US9333205 (2016) BindingDB Entry DOI: 10.7270/Q22F7M9V | |||||||||||
More data for this Ligand-Target Pair |