Affinity Data by Patent

Patent code US10858323

Found 12 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Histone deacetylase 6 (Homo sapiens (Human))	BDBM139295 (US10858323, Compound 1 \| US8614223, 73) Show SMILES ONC(=O)c1cnc(NC2(CC2)c2ccccc2)nc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
REGENACY PHARMACEUTICALS, LLC US Patent					Assay Description Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...				US Patent US10858323 (2020) BindingDB Entry DOI: 10.7270/Q2W09918
REGENACY PHARMACEUTICALS, LLC US Patent					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM473794 (N-hydroxy-2-((2-methoxy-5-(trifluoromethyl)benzyl)...) Show SMILES COc1ccc(cc1CNc1ncc(cn1)C(=O)NO)C(F)(F)F Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
REGENACY PHARMACEUTICALS, LLC US Patent					Assay Description Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...				US Patent US10858323 (2020) BindingDB Entry DOI: 10.7270/Q2W09918
REGENACY PHARMACEUTICALS, LLC US Patent					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50439674 (RICOLINOSTAT \| US10858323, Compound 2 \| US11207431...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
REGENACY PHARMACEUTICALS, LLC US Patent					Assay Description Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...				US Patent US10858323 (2020) BindingDB Entry DOI: 10.7270/Q2W09918
REGENACY PHARMACEUTICALS, LLC US Patent					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50439674 (RICOLINOSTAT \| US10858323, Compound 2 \| US11207431...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	US Patent	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
REGENACY PHARMACEUTICALS, LLC US Patent					Assay Description Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...				US Patent US10858323 (2020) BindingDB Entry DOI: 10.7270/Q2W09918
REGENACY PHARMACEUTICALS, LLC US Patent					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM50439674 (RICOLINOSTAT \| US10858323, Compound 2 \| US11207431...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	US Patent	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
REGENACY PHARMACEUTICALS, LLC US Patent					Assay Description Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...				US Patent US10858323 (2020) BindingDB Entry DOI: 10.7270/Q2W09918
REGENACY PHARMACEUTICALS, LLC US Patent					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM473794 (N-hydroxy-2-((2-methoxy-5-(trifluoromethyl)benzyl)...) Show SMILES COc1ccc(cc1CNc1ncc(cn1)C(=O)NO)C(F)(F)F Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
REGENACY PHARMACEUTICALS, LLC US Patent					Assay Description Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...				US Patent US10858323 (2020) BindingDB Entry DOI: 10.7270/Q2W09918
REGENACY PHARMACEUTICALS, LLC US Patent					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM473794 (N-hydroxy-2-((2-methoxy-5-(trifluoromethyl)benzyl)...) Show SMILES COc1ccc(cc1CNc1ncc(cn1)C(=O)NO)C(F)(F)F Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
REGENACY PHARMACEUTICALS, LLC US Patent					Assay Description Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...				US Patent US10858323 (2020) BindingDB Entry DOI: 10.7270/Q2W09918
REGENACY PHARMACEUTICALS, LLC US Patent					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM50439674 (RICOLINOSTAT \| US10858323, Compound 2 \| US11207431...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	US Patent	n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
REGENACY PHARMACEUTICALS, LLC US Patent					Assay Description Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...				US Patent US10858323 (2020) BindingDB Entry DOI: 10.7270/Q2W09918
REGENACY PHARMACEUTICALS, LLC US Patent					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM139295 (US10858323, Compound 1 \| US8614223, 73) Show SMILES ONC(=O)c1cnc(NC2(CC2)c2ccccc2)nc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	US Patent	n/a	n/a	94	n/a	n/a	n/a	n/a	n/a	n/a
REGENACY PHARMACEUTICALS, LLC US Patent					Assay Description Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...				US Patent US10858323 (2020) BindingDB Entry DOI: 10.7270/Q2W09918
REGENACY PHARMACEUTICALS, LLC US Patent					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM473794 (N-hydroxy-2-((2-methoxy-5-(trifluoromethyl)benzyl)...) Show SMILES COc1ccc(cc1CNc1ncc(cn1)C(=O)NO)C(F)(F)F Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	105	n/a	n/a	n/a	n/a	n/a	n/a
REGENACY PHARMACEUTICALS, LLC US Patent					Assay Description Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...				US Patent US10858323 (2020) BindingDB Entry DOI: 10.7270/Q2W09918
REGENACY PHARMACEUTICALS, LLC US Patent					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM139295 (US10858323, Compound 1 \| US8614223, 73) Show SMILES ONC(=O)c1cnc(NC2(CC2)c2ccccc2)nc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	US Patent	n/a	n/a	128	n/a	n/a	n/a	n/a	n/a	n/a
REGENACY PHARMACEUTICALS, LLC US Patent					Assay Description Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...				US Patent US10858323 (2020) BindingDB Entry DOI: 10.7270/Q2W09918
REGENACY PHARMACEUTICALS, LLC US Patent					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM139295 (US10858323, Compound 1 \| US8614223, 73) Show SMILES ONC(=O)c1cnc(NC2(CC2)c2ccccc2)nc1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	US Patent	n/a	n/a	158	n/a	n/a	n/a	n/a	n/a	n/a
REGENACY PHARMACEUTICALS, LLC US Patent					Assay Description Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...				US Patent US10858323 (2020) BindingDB Entry DOI: 10.7270/Q2W09918
REGENACY PHARMACEUTICALS, LLC US Patent					More data for this Ligand-Target Pair

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* indicates data uncertainty>20%