| Reaction Details |
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 | Report a problem with these data |
| Target | Histone deacetylase 3 |
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| Ligand | BDBM139295 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | HDAC Enzyme Assays |
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| IC50 | 158±n/a nM |
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| Citation |  Golonzhka, O; Jarpe, MB HDAC inhibitors for the treatment of diabetic peripheral neuropathy US Patent US10858323 Publication Date 12/8/2020 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Histone deacetylase 3 |
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| Name: | Histone deacetylase 3 |
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| Synonyms: | HD3 | HDAC3 | HDAC3_HUMAN | Histone deacetylase 3 (HDAC3) | Human HDAC3 | RPD3-2 | SMAP45 |
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| Type: | Enzyme |
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| Mol. Mass.: | 48829.55 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O15379 |
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| Residue: | 428 |
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| Sequence: | MAKTVAYFYDPDVGNFHYGAGHPMKPHRLALTHSLVLHYGLYKKMIVFKPYQASQHDMCR
FHSEDYIDFLQRVSPTNMQGFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQGATQLNN
KICDIAINWAGGLHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYIDIDIHHGDGVQEA
FYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYKHLFQPVI
NQVVDFYQPTCIVLQCGADSLGCDRLGCFNLSIRGHGECVEYVKSFNIPLLVLGGGGYTV
RNVARCWTYETSLLVEEAISEELPYSEYFEYFAPDFTLHPDVSTRIENQNSRQYLDQIRQ
TIFENLKMLNHAPSVQIHDVPADLLTYDRTDEADAEERGPEENYSRPEAPNEFYDGDHDN
DKESDVEI
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| BDBM139295 |
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| n/a |
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| Name | BDBM139295 |
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| Synonyms: | US10858323, Compound 1 | US8614223, 73 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H14N4O2 |
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| Mol. Mass. | 270.2866 |
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| SMILES | ONC(=O)c1cnc(NC2(CC2)c2ccccc2)nc1 |
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| Structure | 
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