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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Glycogen synthase kinase-3 beta (Homo sapiens (Human)) | BDBM119688 (US8686042, 1-Benzyl-3-naphthalen-1-yl-urea) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet  | Purchase MCE PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 17.1 | n/a | n/a | n/a | n/a | 7.3 | 30 |
Neuropharma, S.A. US Patent | Assay Description The GSK-3β activity was determined by incubation of a mixture of recombinant human GSK-3 enzyme, a phosphate source and GSK-3 substrate in the p... | US Patent US8686042 (2014) BindingDB Entry DOI: 10.7270/Q2H993V7 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Glycogen synthase kinase-3 beta (Homo sapiens (Human)) | BDBM119689 (US8686042, 1-Benzo[1,3]dioxol-5-yl-3-benzyl-urea) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 38.4 | n/a | n/a | n/a | n/a | 7.3 | 30 |
Neuropharma, S.A. US Patent | Assay Description The GSK-3β activity was determined by incubation of a mixture of recombinant human GSK-3 enzyme, a phosphate source and GSK-3 substrate in the p... | US Patent US8686042 (2014) BindingDB Entry DOI: 10.7270/Q2H993V7 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
