Affinity Data by Patent

Patent code US9469613

Found 4 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Activin receptor type-1 (Homo sapiens (Human))	BDBM50311017 (CHEMBL1078178 \| Momelotinib \| N-(cyanomethyl)-4-(2...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB US Patent	n/a	n/a	8	25	n/a	n/a	n/a	n/a	n/a
GILEAD SCIENCES, INC. US Patent					Assay Description Biochemical binding assays (DiscoveRx) and in vitro enzyme inhibition assays (LanthaScreen, Life Technologies) were conducted to determine the bindin...				US Patent US9469613 (2016) BindingDB Entry DOI: 10.7270/Q2J1024J
GILEAD SCIENCES, INC. US Patent					More data for this Ligand-Target Pair				3D Structure (crystal)
Bone morphogenetic protein receptor type-1B (Homo sapiens (Human))	BDBM50311017 (CHEMBL1078178 \| Momelotinib \| N-(cyanomethyl)-4-(2...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	US Patent	n/a	n/a	107	19	n/a	n/a	n/a	n/a	n/a
GILEAD SCIENCES, INC. US Patent					Assay Description Biochemical binding assays (DiscoveRx) and in vitro enzyme inhibition assays (LanthaScreen, Life Technologies) were conducted to determine the bindin...				US Patent US9469613 (2016) BindingDB Entry DOI: 10.7270/Q2J1024J
GILEAD SCIENCES, INC. US Patent					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50311017 (CHEMBL1078178 \| Momelotinib \| N-(cyanomethyl)-4-(2...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	US Patent	n/a	n/a	205	670	n/a	n/a	n/a	n/a	n/a
GILEAD SCIENCES, INC. US Patent					Assay Description Biochemical binding assays (DiscoveRx) and in vitro enzyme inhibition assays (LanthaScreen, Life Technologies) were conducted to determine the bindin...				US Patent US9469613 (2016) BindingDB Entry DOI: 10.7270/Q2J1024J
GILEAD SCIENCES, INC. US Patent					More data for this Ligand-Target Pair
Bone morphogenetic protein receptor type-1A (Homo sapiens (Human))	BDBM50311017 (CHEMBL1078178 \| Momelotinib \| N-(cyanomethyl)-4-(2...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	US Patent	n/a	n/a	405	1.00E+3	n/a	n/a	n/a	n/a	n/a
GILEAD SCIENCES, INC. US Patent					Assay Description Biochemical binding assays (DiscoveRx) and in vitro enzyme inhibition assays (LanthaScreen, Life Technologies) were conducted to determine the bindin...				US Patent US9469613 (2016) BindingDB Entry DOI: 10.7270/Q2J1024J
GILEAD SCIENCES, INC. US Patent					More data for this Ligand-Target Pair

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* indicates data uncertainty>20%