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Patent code US8993765

Compile Data Set for Download or QSAR
Found 26 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM153245
PNG
(US8993765, 10)
Show SMILES Cl.Cn1c2CCNCc2c2ccc(nc12)-n1ccc(cc1=O)-c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C23H19F3N4O.ClH/c1-29-19-8-10-27-13-18(19)17-6-7-20(28-22(17)29)30-11-9-15(12-21(30)31)14-2-4-16(5-3-14)23(24,25)26;/h2-7,9,11-12,27H,8,10,13H2,1H3;1H
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 4.70n/an/an/an/an/an/a7.4n/a



Albany Molecular Research, Inc.

US Patent


Assay Description
Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...

US Patent US8993765 (2015)


BindingDB Entry DOI: 10.7270/Q2QZ28Q8
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM153237
PNG
(US8993765, 2)
Show SMILES Cl.Cn1c2CCNCc2c2ccc(nc12)-n1ccc(OCc2ccccc2)cc1=O
Show InChI InChI=1S/C23H22N4O2.ClH/c1-26-20-9-11-24-14-19(20)18-7-8-21(25-23(18)26)27-12-10-17(13-22(27)28)29-15-16-5-3-2-4-6-16;/h2-8,10,12-13,24H,9,11,14-15H2,1H3;1H
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US Patent
 7.10n/an/an/an/an/an/a7.4n/a



Albany Molecular Research, Inc.

US Patent


Assay Description
Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...

US Patent US8993765 (2015)


BindingDB Entry DOI: 10.7270/Q2QZ28Q8
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM153251
PNG
(US8993765, 16)
Show SMILES Cl.Cn1c2CCNCc2c2ccc(nc12)-n1ccc(OCc2ccc(F)cc2F)cc1=O
Show InChI InChI=1S/C23H20F2N4O2.ClH/c1-28-20-6-8-26-12-18(20)17-4-5-21(27-23(17)28)29-9-7-16(11-22(29)30)31-13-14-2-3-15(24)10-19(14)25;/h2-5,7,9-11,26H,6,8,12-13H2,1H3;1H
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 8.30n/an/an/an/an/an/a7.4n/a



Albany Molecular Research, Inc.

US Patent


Assay Description
Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...

US Patent US8993765 (2015)


BindingDB Entry DOI: 10.7270/Q2QZ28Q8
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM153252
PNG
(US8993765, 17)
Show SMILES CC1Cc2c(CN1)c1ccc(nc1n2C)-n1ccc(OCc2ccccc2)cc1=O
Show InChI InChI=1S/C24H24N4O2/c1-16-12-21-20(14-25-16)19-8-9-22(26-24(19)27(21)2)28-11-10-18(13-23(28)29)30-15-17-6-4-3-5-7-17/h3-11,13,16,25H,12,14-15H2,1-2H3
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 9.10n/an/an/an/an/an/a7.4n/a



Albany Molecular Research, Inc.

US Patent


Assay Description
Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...

US Patent US8993765 (2015)


BindingDB Entry DOI: 10.7270/Q2QZ28Q8
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM153248
PNG
(US8993765, 13)
Show SMILES Cl.CC1Cc2c(CN1)c1ccc(nc1n2C)-n1ccc(OCc2ccccc2)cc1=O
Show InChI InChI=1S/C24H24N4O2/c1-16-12-21-20(14-25-16)19-8-9-22(26-24(19)27(21)2)28-11-10-18(13-23(28)29)30-15-17-6-4-3-5-7-17/h3-11,13,16,25H,12,14-15H2,1-2H3
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 9.30n/an/an/an/an/an/a7.4n/a



Albany Molecular Research, Inc.

US Patent


Assay Description
Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...

US Patent US8993765 (2015)


BindingDB Entry DOI: 10.7270/Q2QZ28Q8
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM153239
PNG
(US8993765, 4)
Show SMILES Cl.Cn1c2CCNCc2c2ccc(nc12)-n1ccc(OCc2ccc(F)cn2)cc1=O
Show InChI InChI=1S/C22H20FN5O2.ClH/c1-27-19-6-8-24-12-18(19)17-4-5-20(26-22(17)27)28-9-7-16(10-21(28)29)30-13-15-3-2-14(23)11-25-15;/h2-5,7,9-11,24H,6,8,12-13H2,1H3;1H
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 15n/an/an/an/an/an/a7.4n/a



Albany Molecular Research, Inc.

US Patent


Assay Description
Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...

US Patent US8993765 (2015)


BindingDB Entry DOI: 10.7270/Q2QZ28Q8
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM153241
PNG
(US8993765, 6)
Show SMILES Cl.Cn1c2CCNCc2c2ccc(nc12)-n1ccc(cc1=O)-c1ccc(nc1)C(F)(F)F
Show InChI InChI=1S/C22H18F3N5O.ClH/c1-29-17-6-8-26-12-16(17)15-3-5-19(28-21(15)29)30-9-7-13(10-20(30)31)14-2-4-18(27-11-14)22(23,24)25;/h2-5,7,9-11,26H,6,8,12H2,1H3;1H
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 15n/an/an/an/an/an/a7.4n/a



Albany Molecular Research, Inc.

US Patent


Assay Description
Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...

US Patent US8993765 (2015)


BindingDB Entry DOI: 10.7270/Q2QZ28Q8
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM153250
PNG
(US8993765, 15)
Show SMILES Cl.Cn1c2CCNCc2c2ccc(nc12)-n1ccc(OCc2ccc(Cl)cc2Cl)cc1=O
Show InChI InChI=1S/C23H20Cl2N4O2.ClH/c1-28-20-6-8-26-12-18(20)17-4-5-21(27-23(17)28)29-9-7-16(11-22(29)30)31-13-14-2-3-15(24)10-19(14)25;/h2-5,7,9-11,26H,6,8,12-13H2,1H3;1H
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 17n/an/an/an/an/an/a7.4n/a



Albany Molecular Research, Inc.

US Patent


Assay Description
Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...

US Patent US8993765 (2015)


BindingDB Entry DOI: 10.7270/Q2QZ28Q8
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM153260
PNG
(US8993765, 27)
Show SMILES Cl.CC(C)N1CCc2nc3cc(ccn3c2C1)-n1ccc(OCc2ccccc2)cc1=O
Show InChI InChI=1S/C25H26N4O2.ClH/c1-18(2)27-11-10-22-23(16-27)29-12-8-20(14-24(29)26-22)28-13-9-21(15-25(28)30)31-17-19-6-4-3-5-7-19;/h3-9,12-15,18H,10-11,16-17H2,1-2H3;1H
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 19n/an/an/an/an/an/a7.4n/a



Albany Molecular Research, Inc.

US Patent


Assay Description
Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...

US Patent US8993765 (2015)


BindingDB Entry DOI: 10.7270/Q2QZ28Q8
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM153255
PNG
(US8993765, 22)
Show SMILES Cl.O=c1cc(OCc2ccccc2)ccn1-c1ccn2c3CNCCc3nc2c1
Show InChI InChI=1S/C22H20N4O2.ClH/c27-22-13-18(28-15-16-4-2-1-3-5-16)8-11-25(22)17-7-10-26-20-14-23-9-6-19(20)24-21(26)12-17;/h1-5,7-8,10-13,23H,6,9,14-15H2;1H
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 21n/an/an/an/an/an/a7.4n/a



Albany Molecular Research, Inc.

US Patent


Assay Description
Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...

US Patent US8993765 (2015)


BindingDB Entry DOI: 10.7270/Q2QZ28Q8
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM153259
PNG
(US8993765, 26)
Show SMILES Cl.FC(F)(F)c1ccc(cc1)-c1ccn(-c2ccn3c4CNCCc4nc3c2)c(=O)c1
Show InChI InChI=1S/C22H17F3N4O.ClH/c23-22(24,25)16-3-1-14(2-4-16)15-6-9-28(21(30)11-15)17-7-10-29-19-13-26-8-5-18(19)27-20(29)12-17;/h1-4,6-7,9-12,26H,5,8,13H2;1H
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 23n/an/an/an/an/an/a7.4n/a



Albany Molecular Research, Inc.

US Patent


Assay Description
Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...

US Patent US8993765 (2015)


BindingDB Entry DOI: 10.7270/Q2QZ28Q8
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM153249
PNG
(US8993765, 14)
Show SMILES Cl.CC1Cc2c(CN1)c1ccc(nc1n2C)-n1ccc(OCc2ccc(F)cn2)cc1=O
Show InChI InChI=1S/C23H22FN5O2/c1-14-9-20-19(12-25-14)18-5-6-21(27-23(18)28(20)2)29-8-7-17(10-22(29)30)31-13-16-4-3-15(24)11-26-16/h3-8,10-11,14,25H,9,12-13H2,1-2H3
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 25n/an/an/an/an/an/a7.4n/a



Albany Molecular Research, Inc.

US Patent


Assay Description
Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...

US Patent US8993765 (2015)


BindingDB Entry DOI: 10.7270/Q2QZ28Q8
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM153256
PNG
(US8993765, 23)
Show SMILES Cl.Fc1ccc(COc2ccn(-c3ccn4c5CNCCc5nc4c3)c(=O)c2)nc1
Show InChI InChI=1S/C21H18FN5O2.ClH/c22-14-1-2-15(24-11-14)13-29-17-5-8-26(21(28)10-17)16-4-7-27-19-12-23-6-3-18(19)25-20(27)9-16;/h1-2,4-5,7-11,23H,3,6,12-13H2;1H
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 30n/an/an/an/an/an/a7.4n/a



Albany Molecular Research, Inc.

US Patent


Assay Description
Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...

US Patent US8993765 (2015)


BindingDB Entry DOI: 10.7270/Q2QZ28Q8
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM153243
PNG
(US8993765, 8)
Show SMILES Cl.Cn1c2CCNCc2c2ccc(nc12)-n1ccc(cc1=O)-c1ccc(cn1)C(F)(F)F
Show InChI InChI=1S/C22H18F3N5O.ClH/c1-29-18-6-8-26-12-16(18)15-3-5-19(28-21(15)29)30-9-7-13(10-20(30)31)17-4-2-14(11-27-17)22(23,24)25;/h2-5,7,9-11,26H,6,8,12H2,1H3;1H
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 33n/an/an/an/an/an/a7.4n/a



Albany Molecular Research, Inc.

US Patent


Assay Description
Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...

US Patent US8993765 (2015)


BindingDB Entry DOI: 10.7270/Q2QZ28Q8
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM153238
PNG
(US8993765, 3)
Show SMILES Cl.Cn1c2CCNCc2c2ccc(nc12)N1CCN(CCc2ccccc2)CC1=O
Show InChI InChI=1S/C23H27N5O.ClH/c1-26-20-9-11-24-15-19(20)18-7-8-21(25-23(18)26)28-14-13-27(16-22(28)29)12-10-17-5-3-2-4-6-17;/h2-8,24H,9-16H2,1H3;1H
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 47n/an/an/an/an/an/a7.4n/a



Albany Molecular Research, Inc.

US Patent


Assay Description
Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...

US Patent US8993765 (2015)


BindingDB Entry DOI: 10.7270/Q2QZ28Q8
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM153247
PNG
(US8993765, 12)
Show SMILES Cl.CC1Cc2c(CN1)c1ccc(nc1n2C)N1CCN(CCc2ccc(F)cc2)CC1=O
Show InChI InChI=1S/C24H28FN5O/c1-16-13-21-20(14-26-16)19-7-8-22(27-24(19)28(21)2)30-12-11-29(15-23(30)31)10-9-17-3-5-18(25)6-4-17/h3-8,16,26H,9-15H2,1-2H3
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 58n/an/an/an/an/an/a7.4n/a



Albany Molecular Research, Inc.

US Patent


Assay Description
Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...

US Patent US8993765 (2015)


BindingDB Entry DOI: 10.7270/Q2QZ28Q8
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM153253
PNG
(US8993765, 18)
Show SMILES Cl.O=c1cc(OCc2ccccc2)ccn1-c1ccc2n3CCNCc3nc2c1
Show InChI InChI=1S/C22H20N4O2.ClH/c27-22-13-18(28-15-16-4-2-1-3-5-16)8-10-25(22)17-6-7-20-19(12-17)24-21-14-23-9-11-26(20)21;/h1-8,10,12-13,23H,9,11,14-15H2;1H
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 62n/an/an/an/an/an/a7.4n/a



Albany Molecular Research, Inc.

US Patent


Assay Description
Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...

US Patent US8993765 (2015)


BindingDB Entry DOI: 10.7270/Q2QZ28Q8
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM153246
PNG
(US8993765, 11)
Show SMILES Cl.CC(=O)N1CCc2c(C1)c1ccc(nc1n2C)-n1ccc(OCc2ccccc2)cc1=O
Show InChI InChI=1S/C25H24N4O3.ClH/c1-17(30)28-12-11-22-21(15-28)20-8-9-23(26-25(20)27(22)2)29-13-10-19(14-24(29)31)32-16-18-6-4-3-5-7-18;/h3-10,13-14H,11-12,15-16H2,1-2H3;1H
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 71n/an/an/an/an/an/a7.4n/a



Albany Molecular Research, Inc.

US Patent


Assay Description
Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...

US Patent US8993765 (2015)


BindingDB Entry DOI: 10.7270/Q2QZ28Q8
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM153242
PNG
(US8993765, 7)
Show SMILES Cl.Cn1c2CCNCc2c2ccc(nc12)-n1ccc(OCc2ccc(nc2)C(F)(F)F)cc1=O
Show InChI InChI=1S/C23H20F3N5O2.ClH/c1-30-18-6-8-27-12-17(18)16-3-5-20(29-22(16)30)31-9-7-15(10-21(31)32)33-13-14-2-4-19(28-11-14)23(24,25)26;/h2-5,7,9-11,27H,6,8,12-13H2,1H3;1H
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 71n/an/an/an/an/an/a7.4n/a



Albany Molecular Research, Inc.

US Patent


Assay Description
Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...

US Patent US8993765 (2015)


BindingDB Entry DOI: 10.7270/Q2QZ28Q8
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM153244
PNG
(US8993765, 9)
Show SMILES Cl.CC(=O)N1CCc2c(C1)c1ccc(nc1n2C)-n1ccc(cc1=O)-c1ccc(nc1)C(F)(F)F
Show InChI InChI=1S/C24H20F3N5O2.ClH/c1-14(33)31-9-8-19-18(13-31)17-4-6-21(29-23(17)30(19)2)32-10-7-15(11-22(32)34)16-3-5-20(28-12-16)24(25,26)27;/h3-7,10-12H,8-9,13H2,1-2H3;1H
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 78n/an/an/an/an/an/a7.4n/a



Albany Molecular Research, Inc.

US Patent


Assay Description
Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...

US Patent US8993765 (2015)


BindingDB Entry DOI: 10.7270/Q2QZ28Q8
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM153262
PNG
(US8993765, 29)
Show SMILES CC1Cc2c(CN1C(C)=O)c1ccc(nc1n2C)-n1ccc(OCc2ccccc2)cc1=O
Show InChI InChI=1S/C26H26N4O3/c1-17-13-23-22(15-30(17)18(2)31)21-9-10-24(27-26(21)28(23)3)29-12-11-20(14-25(29)32)33-16-19-7-5-4-6-8-19/h4-12,14,17H,13,15-16H2,1-3H3
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 81n/an/an/an/an/an/a7.4n/a



Albany Molecular Research, Inc.

US Patent


Assay Description
Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...

US Patent US8993765 (2015)


BindingDB Entry DOI: 10.7270/Q2QZ28Q8
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM153254
PNG
(US8993765, 21)
Show SMILES Cl.CC(C)N1CCn2c(C1)nc1cc(ccc21)-n1ccc(OCc2ccccc2)cc1=O
Show InChI InChI=1S/C25H26N4O2.ClH/c1-18(2)27-12-13-29-23-9-8-20(14-22(23)26-24(29)16-27)28-11-10-21(15-25(28)30)31-17-19-6-4-3-5-7-19;/h3-11,14-15,18H,12-13,16-17H2,1-2H3;1H
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 94n/an/an/an/an/an/a7.4n/a



Albany Molecular Research, Inc.

US Patent


Assay Description
Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...

US Patent US8993765 (2015)


BindingDB Entry DOI: 10.7270/Q2QZ28Q8
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM153261
PNG
(US8993765, 28)
Show SMILES Cn1c2CCNC(=O)c2c2ccc(nc12)-n1ccc(OCc2ccccc2)cc1=O
Show InChI InChI=1S/C23H20N4O3/c1-26-18-9-11-24-23(29)21(18)17-7-8-19(25-22(17)26)27-12-10-16(13-20(27)28)30-14-15-5-3-2-4-6-15/h2-8,10,12-13H,9,11,14H2,1H3,(H,24,29)
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 103n/an/an/an/an/an/a7.4n/a



Albany Molecular Research, Inc.

US Patent


Assay Description
Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...

US Patent US8993765 (2015)


BindingDB Entry DOI: 10.7270/Q2QZ28Q8
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM153240
PNG
(US8993765, 5)
Show SMILES Cl.Cn1c2CCNCc2c2ccc(nc12)-n1ccc(cc1=O)-c1ccc(nn1)C(F)(F)F
Show InChI InChI=1S/C21H17F3N6O.ClH/c1-29-16-6-8-25-11-14(16)13-2-5-18(26-20(13)29)30-9-7-12(10-19(30)31)15-3-4-17(28-27-15)21(22,23)24;/h2-5,7,9-10,25H,6,8,11H2,1H3;1H
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 105n/an/an/an/an/an/a7.4n/a



Albany Molecular Research, Inc.

US Patent


Assay Description
Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...

US Patent US8993765 (2015)


BindingDB Entry DOI: 10.7270/Q2QZ28Q8
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM153257
PNG
(US8993765, 24)
Show SMILES Cl.FC(F)(F)c1ccc(cn1)-c1ccn(-c2ccn3c4CNCCc4nc3c2)c(=O)c1
Show InChI InChI=1S/C21H16F3N5O.ClH/c22-21(23,24)18-2-1-14(11-26-18)13-4-7-28(20(30)9-13)15-5-8-29-17-12-25-6-3-16(17)27-19(29)10-15;/h1-2,4-5,7-11,25H,3,6,12H2;1H
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 616n/an/an/an/an/an/a7.4n/a



Albany Molecular Research, Inc.

US Patent


Assay Description
Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...

US Patent US8993765 (2015)


BindingDB Entry DOI: 10.7270/Q2QZ28Q8
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM153258
PNG
(US8993765, 25)
Show SMILES Cl.FC(F)(F)c1ccc(COc2ccn(-c3ccn4c5CNCCc5nc4c3)c(=O)c2)cn1
Show InChI InChI=1S/C22H18F3N5O2.ClH/c23-22(24,25)19-2-1-14(11-27-19)13-32-16-5-8-29(21(31)10-16)15-4-7-30-18-12-26-6-3-17(18)28-20(30)9-15;/h1-2,4-5,7-11,26H,3,6,12-13H2;1H
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 3.32E+3n/an/an/an/an/an/a7.4n/a



Albany Molecular Research, Inc.

US Patent


Assay Description
Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...

US Patent US8993765 (2015)


BindingDB Entry DOI: 10.7270/Q2QZ28Q8
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%