The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
26670264 |
73 |
Fragment-Based Discovery of 2-Aminoquinazolin-4(3H)-ones As Novel Class Nonpeptidomimetic Inhibitors of the Plasmepsins I, II, and IV. |
Latvian Institute of Organic Synthesis |
24900843 |
60 |
Plasmepsin inhibitory activity and structure-guided optimization of a potent hydroxyethylamine-based antimalarial hit. |
Latvian Institute of Organic Synthesis |
10669559 |
180 |
Protease inhibitors: current status and future prospects. |
University of Queensland |
19635672 |
35 |
alpha-Substituted norstatines as the transition-state mimic in inhibitors of multiple digestive vacuole malaria aspartic proteases. |
Uppsala University |
19328682 |
13 |
Expedient solid-phase synthesis of both symmetric and asymmetric diol libraries targeting aspartic proteases. |
National University of Singapore |
17149873 |
20 |
High antiplasmodial activity of novel plasmepsins I and II inhibitors. |
University of Milan |
16162010 |
78 |
Synthesis of malarial plasmepsin inhibitors and prediction of binding modes by molecular dynamics simulations. |
Uppsala University |
15974592 |
68 |
Design and synthesis of potent inhibitors of plasmepsin I and II: X-ray crystal structure of inhibitor in complex with plasmepsin II. |
LinköPing University |
31913032 |
86 |
Plasmepsin Inhibitors in Antimalarial Drug Discovery: Medicinal Chemistry and Target Validation (2000 to Present). |
University of Zambia |
30529637 |
76 |
Peptidomimetic plasmepsin inhibitors with potent anti-malarial activity and selectivity against cathepsin D. |
Latvian Institute of Organic Synthesis |
29636223 |
84 |
2-Aminoquinazolin-4(3H)-one based plasmepsin inhibitors with improved hydrophilicity and selectivity. |
Latvian Institute of Organic Synthesis |
15658851 |
42 |
Selective estrogen receptor modulators with conformationally restricted side chains. Synthesis and structure-activity relationship of ERalpha-selective tetrahydroisoquinoline ligands. |
Novartis Pharmaceuticals |
15689158 |
21 |
Novel transient receptor potential vanilloid 1 receptor antagonists for the treatment of pain: structure-activity relationships for ureas with quinoline, isoquinoline, quinazoline, phthalazine, quinoxaline, and cinnoline moieties. |
Abbott Laboratories |
18072720 |
30 |
Stereospecific high-affinity TRPV1 antagonists: chiral N-(2-Benzyl-3-pivaloyloxypropyl) 2-[4-(methylsulfonylamino)phenyl]propionamide analogues. |
Seoul National University |
12639546 |
30 |
Identification of a high-affinity phosphopeptide inhibitor of Stat3. |
The University of Texas At Houston |