The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
| 58 |
Non-glycosidic/non-aminoalkyl-substituted indolocarbazoles as inhibitors of protein kinase C |
TBA |
11451670 |
11 |
Hexosaminidase inhibitors as new drug candidates for the therapy of osteoarthritis. |
The Scripps Research Institute |
10322126 |
60 |
Structure-based discovery and in-parallel optimization of novel competitive inhibitors of thymidylate synthase. |
Northwestern University |
16789731 |
3 |
Discovery of a nanomolar inhibitor of the human murine double minute 2 (MDM2)-p53 interaction through an integrated, virtual database screening strategy. |
University of Michigan |
16759082 |
9 |
Structure-based design of spiro-oxindoles as potent, specific small-molecule inhibitors of the MDM2-p53 interaction. |
University of Michigan |
19072652 |
64 |
Synthesis and evaluation of novel inhibitors of Pim-1 and Pim-2 protein kinases. |
Medical University of South Carolina |
17614275 |
16 |
Benzopyrans as selective estrogen receptor beta agonists (SERBAs). Part 3: synthesis of cyclopentanone and cyclohexanone intermediates for C-ring modification. |
Eli Lilly |
11567092 |
4 |
Crystal structure of Staphylococcus aureus tyrosyl-tRNA synthetase in complex with a class of potent and specific inhibitors. |
Gsk |
17049867 |
5 |
Synthesis of beta-ketophosphonate analogs of glutamyl and glutaminyl adenylate, and selective inhibition of the corresponding bacterial aminoacyl-tRNA synthetases. |
Crefsip |
17444623 |
29 |
Discovery of the HCV NS3/4A protease inhibitor (1R,5S)-N-[3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]-3- [2(S)-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]- 6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2(S)-carboxamide (Sch 503034) II. Key steps in structure-based optimization. |
Schering-Plough Research Institute |
17120228 |
14 |
Serendipitous discovery of novel bacterial methionine aminopeptidase inhibitors. |
The Procter & Gamble Pharmaceuticals |
17696512 |
50 |
Design and Synthesis of HIV-1 Protease Inhibitors Incorporating Oxazolidinones as P2/P2' Ligands in Pseudosymmetric Dipeptide Isosteres. |
University of Massachusetts Medical School |
16495061 |
8 |
Selection of a 2-azabicyclo[2.2.2]octane-based alpha4beta1 integrin antagonist as an inhaled anti-asthmatic agent. |
Johnson & Johnson Pharmaceutical |
16982192 |
8 |
Arylsulfonamides: a study of the relationship between activity and conformational preferences for a series of factor Xa inhibitors. |
Glaxosmithkline |
16279769 |
28 |
Synthesis, molecular modeling studies, and selective inhibitory activity against monoamine oxidase of 1-thiocarbamoyl-3,5-diaryl-4,5-dihydro-(1H)- pyrazole derivatives. |
Sapienza University of Rome |
15689148 |
19 |
Bis-huperzine B: highly potent and selective acetylcholinesterase inhibitors. |
Shanghai Institute of Materia Medica |
15985434 |
18 |
Crystal structure of pyridoxal kinase in complex with roscovitine and derivatives. |
Chinese Academy of Sciences |
15664516 |
21 |
Specificity and affinity of natural product cyclopentapeptide inhibitors against A. fumigatus, human, and bacterial chitinases. |
University of Dundee |
16023344 |
120 |
Lipophilic versus hydrogen-bonding effect in P3 on potency and selectivity of valine aspartyl ketones as caspase 3 inhibitors. |
Merck Frosst Canada |
12852749 |
11 |
First dual aromatase-steroid sulfatase inhibitors. |
University of Bath |
8667367 |
28 |
Synthesis and structure-activity relationships of 6-substituted androst-4-ene analogs as aromatase inhibitors. |
Tohoku College of Pharmacy |
15911319 |
10 |
Synthesis and characterization of azole isoflavone inhibitors of aromatase. |
Ohio State University |