The following articles (labelled with PubMed ID or TBD) are for your review
| PMID | Data | Article Title | Organization |
|---|
| 9554869 |
15 |
Rational drug design approach for overcoming drug resistance: application to pyrimethamine resistance in malaria. |
University of Manchester |
| 16750361 |
11 |
Analysis of complexes of inhibitors with Cryptosporidium hominis DHFR leads to a new trimethoprim derivative. |
Dartmouth College |
| 15293997 |
52 |
Three-dimensional quantitative structure-activity relationship analysis of a set of Plasmodium falciparum dihydrofolate reductase inhibitors using a pharmacophore generation approach. |
Università |
| 14736247 |
361 |
Inhibitors of multiple mutants of Plasmodium falciparum dihydrofolate reductase and their antimalarial activities. |
National Center For Genetic Engineering and Biotechnology At Thailand |
| 14711307 |
289 |
Target guided synthesis of 5-benzyl-2,4-diamonopyrimidines: their antimalarial activities and binding affinities to wild type and mutant dihydrofolate reductases from Plasmodium falciparum. |
National Center For Genetic Engineering and Biotechnology At Thailand |
| 12825927 |
84 |
Docking and database screening reveal new classes of Plasmodium falciparum dihydrofolate reductase inhibitors. |
Università |
| 11881993 |
175 |
Development of 2,4-diaminopyrimidines as antimalarials based on inhibition of the S108N and C59R+S108N mutants of dihydrofolate reductase from pyrimethamine-resistant Plasmodium falciparum. |
National Center For Genetic Engineering and Biotechnology At Thailand |
| 29111368 |
43 |
Discovery of new antimalarial agents: Second-generation dual inhibitors against FP-2 and PfDHFR via fragments assembely. |
East China University of Science and Technology |
| 1495020 |
14 |
Probing the molecular basis of resistance to pyrimethamine by site-directed mutagenesis. |
Pennsylvania State University |
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