The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
27818110 |
61 |
Discovery of highly potent and selective orexin 1 receptor antagonists (1-SORAs) suitable for in vivo interrogation of orexin 1 receptor pharmacology. |
Merck Research Laboratories |
26087021 |
94 |
Novel Octahydropyrrolo[3,4-c]pyrroles Are Selective Orexin-2 Antagonists: SAR Leading to a Clinical Candidate. |
TBA |
21831639 |
32 |
Discovery process and pharmacological characterization of a novel dual orexin 1 and orexin 2 receptor antagonist useful for treatment of sleep disorders. |
Glaxosmithkline |